Treatment of Pathophysiological Cases 3750 Case Study
15 pages (3750 words)
, Case Study
A rare complication of warfarin, skin necrosis, is usually seen 2–5 days after initiation of therapy. Well-demarcated erythematous lesions form on the thighs, buttocks, breasts, or toes. The center of the lesion becomes progressively necrotic. Examination of skin biopsies taken from the border of the lesions reveals thrombi in the microvasculature.