quora
Nobody downloaded yet

Animal modeling in drug discovery and development - Essay Example

Comments (0) Cite this document
Summary
According to Hughes, Rees, Kalindjian, and Philpott (2011), the process of developing a drug from a novel idea is an intricate and costly one that takes a period of around 15 years more than one US billion dollars. The main aim during the drug production process is the…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER94.1% of users find it useful
Animal modeling in drug discovery and development
Read TextPreview

Extract of sample
"Animal modeling in drug discovery and development"

Download file to see previous pages The target is described as the molecule or certain biological entities upon which the drug shall act and produce biological reactions that can be measured either in vivo or in vitro.
It is after the identification of the target that the it has to be validated. It is in the authentication that animal models, described as in vitro tools are integrated into the drug discovery and development process (Hughes, et al., 2011). The animal models are used to check for the efficacy of the identified molecule in the target. Most importantly, Mei and Czarnik (2002) indicate that the whole animal model data has to be obtained in order to ascertain the biological linkage of the target to a disease along with how the target can be utilised in the drug discovery and development process. The activity observed in the animal models does not imply decisiveness for the same in human beings, nevertheless, if there lacks any activity, then reconsideration has to be undertaken on the efficacy of the target (Mei & Czarnik, 2002).
The validity of the animal model data is vital in predicting the result for a particular drug during basic research (Denayer, Stohr, & Van Roy, 2014). Furthermore, the validity of the animal model permits for the evaluation of the functional outcomes. It has be recalled that this is in the preclinical trial of the research.
The validity of the animal model data is essential for availing vital information regarding the selectivity and potency of the drug for the human target. The two are vital components in determining if the drug works beyond the preclinical stage of the research. It is so for the in vitro data obtained from the animal models used. At the same time, the in vivo data avails a pharmacodynamics and a pharmacokinetic profile of the drug to be. The pharmacokinetic and the pharmacodynamics of the novel drug under research determines the drug affinity to the identified target and the how well it is distributed to the target. The ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Animal modeling in drug discovery and development Essay”, n.d.)
Animal modeling in drug discovery and development Essay. Retrieved from https://studentshare.org/biology/1685980-animal-modeling-in-drug-discovery-and-development
(Animal Modeling in Drug Discovery and Development Essay)
Animal Modeling in Drug Discovery and Development Essay. https://studentshare.org/biology/1685980-animal-modeling-in-drug-discovery-and-development.
“Animal Modeling in Drug Discovery and Development Essay”, n.d. https://studentshare.org/biology/1685980-animal-modeling-in-drug-discovery-and-development.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
CHECK THESE SAMPLES - THEY ALSO FIT YOUR TOPIC
Pharmacokinetics in drug development: successes and failures
Pharmacokinetics as well as pharmacodynamics are related concepts of in pharmacology. Pharmacodynamics is the study of physiological and biochemical effects of drugs in the bodies of the disease causing microorganisms or parasites residing in other organisms. Drugs are chemical substances administered into the bodies of the organism in order to eliminate a pathogen thereby alleviating the discomfort resulting from such.
5 Pages(1250 words)Essay
Biologics Drug Discovery and Development
As the report stresses biologics can be found in vaccines, blood components and as living cells in therapeutic treatments. Biologics can be actual cells obtained from the body or other components such as sugars or proteins. Biologics is now finding a place in research studies as possible solutions for diseases that have not responded well to traditional drugs. 
5 Pages(1250 words)Essay
Drug Development and Toxicology
Drug development is a gamble; one that involves spending billions of dollars and close to a decade before one can finally say that he has developed a drug that can actually cure a certain disease. Before a drug enters the market, it must undergo different processes that confirm it is fit for use on the patients for whom its developers purposed. 
4 Pages(1000 words)Essay
Targets of Anti-metastatic Drug Development
As a result there has been intense search for both naturally occurring substances and artificially obtained substances that could be helpful in controlling as
6 Pages(1500 words)Essay
Pharmaceutical Industry, New Drug Discovery Research Unit, Anti-bacterial Drug Research
A Ph.D. scientist in the relevant field may be absorbed directly as a leader. Before we look at the role of a leader we must understand the need of the antibacterial drug research. Antibacterial drugs have been the most effective of all medicines.
6 Pages(1500 words)Essay
Drug Development Process
The FDA requires examining the efficacy of the drug thru well-controlled trials, the effectiveness of the drug should be determined and the safety of the drug to be developed is checked before approving the medication for market. The Drug Development Process includes 12 steps;
6 Pages(1500 words)Essay
Modeling and Role Modeling
The theory is named Modeling and Role Modeling. This paper will discuss the theory developed by Erickson as well as how the theory can be integrated into various types of nursing and the results measured. Erickson used several foundation theories in the formation of hers.
4 Pages(1000 words)Essay
Should animals be used for research
This paper presents two sides of the problem: those who are in favor of animal testing and those who oppose it. Animal testing is not as good as it claims to be. It is not
6 Pages(1500 words)Essay
Testing on Animals
Animal testing is sometimes referred to as animal research, animal experimentation or in-vivo testing. Animal testing is mainly carried out in medical schools, research institutes and hospital labs. The testing entails two main categories; the pure research and the
12 Pages(3000 words)Essay
Drug Discovery .. (Translation Of Science Into Medicines)
Traditional drug development process is based on testing thousands of chemical compounds at several target sites in the body to produce a drug that could be used to treat all patients with a particular disease. However, with
2 Pages(500 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Essay on topic Animal modeling in drug discovery and development for FREE!
logo footer
Contact us:
+16312120006
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us