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Life cycle of malaria - Research Paper Example

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Over the years, research has been done to study the malaria parasite. This research has provided vital knowledge on the mechanisms of the plasmodium in the two…
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Life cycle of malaria
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Download file to see previous pages Direct observation has been a challenge. To overcome this hindrance, intravital microscopy along with fluorescence techniques was used.
Conclusions: The success of this research proved that it is possible to observe and study the life cycle of malaria directly. The direct study used in this research opens up a new frontier in the fight against malaria.
The purpose of this research is to comprehend the life cycle of malaria. It is important as it aids researchers in the design and implementation of interventions that can be used to hinder transmission and infection of malaria, and develop respective treatments. Four known plasmodium species are known to cause malaria: plasmodium vivax, ovale, malariae and falciparum (Bozdech, Llinas, Pulliam et al.). It has been proved that it is the female anopheline mosquitoes that transmit the plasmodium. The body of this paper begins with a description of the methods used for the research. The observations are stated after which they are discussed with concluding remarks following thereafter. Briefly looking at the life cycle of malaria, it is well known that they suck human blood as a meal and in turn inject infectious sporozoite stage parasites into people. These sporozoite stage plasmodia enter into the blood circulation and migrate to the liver. In the liver, they invade liver cells and go through replications differentiating into merozoites. The merozoites invade and enter vulnerable erythrocytes from where they go through differentiation and replicate over several days, rupturing and being released from the erythrocytes. They re-enter the blood plasma to begin the blood stage again. The parasites may differentiate into gametocytes while in the blood stage. A feeding mosquito takes them up to begin the cycle once again. This research seeks to answer the question: ‘What occurs in each life cycle stage of Malaria?’ (Hall and Fauci 1640)
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