Nobody downloaded yet

THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM - Lab Report Example

Comments (0) Cite this document
Summary
This class of drug acts upon the 5-HT3 receptor, which is a subtype of the serotonin receptor, located at the terminals of the vegus nerve and in certain areas of the brain. The serotonin (5-HT3) receptor antagonists aid in…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER91.6% of users find it useful
THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM
Read TextPreview

Extract of sample
"THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM"

Download file to see previous pages Q2 (ii): When testing the agonist action of the morphine-like drugs, it is observable that, through the depressant action of the morphine-like drugs, it was difficult to assess the potencies because the tachyphylaxis developed rapidly. In this case, it is important to use small doses of the drug while exposing the gut to the drugs at the intervals that do not go below 30 minutes. The inhibitory effect of morphine on the twitch of longitudinal muscle was induced by the coaxial stimulation, hence leading to the dose-response curve of order ●. Upon sing nalorphine-like drugs, the depressant action of the N-allyl analogue of the morphine was having the similar order to that of morphine. However, tachyphylaxis development was much more rapid with nalorphine than with morphine.
When testing the antagonist action of the morphine-like drugs, tachyphylaxis was able to develop with all compounds tested, which was a strong indication on the possibility of exhibiting antagonist action under suitable conditions. In this experiment, techyphylaxix was able to develop more rapidly than compared to using the agonist. Basing on the agonist activity of the antagonists, the conventional method used for testing antagonism did not yield the decisive results. The antagonism through low concentrations of morphine of the inhibitory effect of morphine upon twitch of the longitudinal muscle was able to induce coaxial stimulation.
Q3: Through using the experimental protocol or two log curves, there is a possibility of an error occurring. To avoid such errors, the formula can be modified into that of the critical ratio approach (CR). The CR is the concentration of agonist at the presence of the antagonist required for producing a fixed response to the linear part of the concentration. It is thus advisable to use the equation that relates CR to KB, which is expressed ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM Lab Report”, n.d.)
Retrieved from https://studentshare.org/biology/1681992-the-actions-of-drugs-on-the-guinea-pig-isolated-ileum
(THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM Lab Report)
https://studentshare.org/biology/1681992-the-actions-of-drugs-on-the-guinea-pig-isolated-ileum.
“THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM Lab Report”, n.d. https://studentshare.org/biology/1681992-the-actions-of-drugs-on-the-guinea-pig-isolated-ileum.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
CHECK THESE SAMPLES - THEY ALSO FIT YOUR TOPIC
Tort actions
...?Week 3 Scenario The tort actions I see in this scenario are the tort of battery (an intentional tort), intentional infliction of emotional distress and the tort of negligence. The potential plaintiffs are Malik and Daniel, who are also the potential defendants in this scenario. I mention that both parties are defendants because there was negligence on behalf of Malik and intentional harm on behalf of Daniel. The elements that I found for each of the plaintiffs claims are as follows: If Malik had not accidentially spilled the beer on Ruben (Daniels son), Daniel would not have got fired from his job, being accused of giving alcohol to a minor. Also, if it were not for Malik following Daniel and his son to the parking lot...
2 Pages(500 words)Essay
Language Development on Isolated Child
...Language Development on Isolated Child Introduction Language development on isolated child is a slow and challenging task. Since children develop their cognitive process and psychological status from the action of their mother, it becomes difficult for an isolated child to learn the basic language at the required time. Therefore, such children tend to experience delaying language. Indeed, their memory might not process the information early enough, as the child who develop with his/her mother. The essay presents a discussion on language development on an isolated child... (Sahin et al., 2009). Such children hardly understand the ways people talk. In developing the language for such children, it is important to assess their pragmatic...
4 Pages(1000 words)Research Paper
Isolated By The Internet
...? English, Essay: Topic: Article essay --“Isolated By The Internet” Analysis Introduction The wise saying that excess of anything is bad, is true of the internet. Internet has covered most of the segments of life of humankind and in the essay “Isolated By the Internet,” Clifford Stoll mentions about the dangers by the excessive use of the internet. The positive outcomes of the internet revolution are many. But there are negative aspects also. Stoll brings forth researched viewpoints of the psychologists and personal observations supported by documented studies in support of his stand. Stoll quotes facts from the research conducted by Carnegie Mellon University psychologists Robert Kraut and Vicki...
3 Pages(750 words)Essay
Cloning of Pig Cells
... Cloning of Pig Cells Introduction Cloning is a technology that has attracted increasing research because of its potential benefits. Cloning involves the production of organisms that are genetically identical to the donor organism. The production of clones occurs through two distinct procedures namely nuclear transfers and splitting of multicellular embryos to create several genetically identical organisms. Cloning has opened a platform that is both scientifically intriguing and beneficial, but also given rise to ethical concerns. Nuclear transfer is the method used in the cloning of different organisms. There have been several successes of cloning especially the birth of Dolly the sheep in 1997, which lived for six...
4 Pages(1000 words)Essay
Non-steroidal Anti-inflammatory Drugs: Actions and Effects
...Non-steroidal Anti-inflammatory Drugs: Actions and Effects What are NSAIDs all about What can be their effects and side effects What could possibly human beings gain from this classification of drugs What could possibly be the explanation of those effects in human beings A non-steroidal anti inflammatory drug is a drug classification that is with specific effects. These drugs, as their classification is named, works as anti inflammatory meaning it reduces inflammation. Non-steroidal anti inflammatory drugs or NSAIDs are said to be the most prescribed medications for treating arthritis. These aren't merely pain relievers...
6 Pages(1500 words)Essay
Public Health in New Guinea
...or treatment. Set up district groups in this country seems to be the best way to handle this. VII. Drug Procurement-The country of New Guinea is a poor country. As stated before, they are listed as the most impoverished in the Pacific region. Treating disease is very difficult given the need for purchase of meds. Setting up and supporting a drug procurement program is gravely necessary at this point in time. VIII. Pregnancy monitoring and education-Infant death rate at this time is 29%. This rate is very high. There are many reasons, natural disasters included but much of this is caused by young mothers. We have mentioned that 40% of the people are under the age of 15 and of course that...
3 Pages(750 words)Essay
Pig Growth Rates in Vietnam
...weight, farm of origin, year of birth, and weight of big after twenty one days concerning a sample of one thousand pigs were collected and recorded. The purpose of the study is to compare growth performance of these two breeds of pigs by analyzing the effect of the different factors monitored in isolation and combined on the growth of pigs represented by their average weight after twenty one days of their birth. 3. Materials and Methods Data were analyzed by ANOVA, linear models, t-tests, regression, and other statistical methods using Office Excel 2003. 4. Empirical Results To determine the relationship between the Day 21 average piglet weight and the various...
8 Pages(2000 words)Article
Drugs
...interactionists believe that an individual may become a drug abuser because of labels which denied them the opportunities. The individual in this case had to resort to drugs to survive. Conflict theory further states that drug abuse creates opportunities for lawmakers to exploit the poor (Devlin, 2006). Functionalists would point out that drug abuse creates more jobs for people in the field of law enforcement. It also creates a means of educating the young and helping maintain conformity in society. Finally symbolic theory states that drug abuse creates a negative image of minorities and poor people. It isolates young people who need...
2 Pages(500 words)Essay
Analysis of data from the practical class (guinea-pig ileum experiments)
...Analysis of data from the practical (guinea-pig ileum experiments On a graph draw your suitably-labelled log concentration – response curves and list the two EC50 values (with units) obtained by your set of 3 students (i.e. for the agonist in the absence and presence of the unknown drug). Graph 1: Comparison of the dose-response curves for contraction in the absence and presence of unknown drug •—•, Contraction (Ach alone); ×—× presence of unknown drug x The fractional deterioration Ach alone curve = baseline 5% maximum= 100% The graph shows that with acetycholine, there was a large displacement between the two curves before the...
2 Pages(500 words)Lab Report
The Dani, Papua New Guinea
...during their lifetimes (Sexton, 1982). The initiation is aimed at eliciting the living plus the ancestors through exchanges of food and valuables. During preparations for war, several pigs are slaughtered in order to call for ancestors help. Head hunting and cannibalism were normally perceived as acquiring bravery, a sign of the deceased good character and also a form of rejuvenation (Sexton, 1982). The wives were accustomed to eating their dead husbands’ body parts in order to maintain their virility while the young warriors carried the enemies heads as a symbol of efficacy and also as a sign of their individual magic. References Heider, K. (1970). Dani; A Papuan Culture in the Highlands of West New...
6 Pages(1500 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Lab Report on topic THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM for FREE!
Contact Us