This class of drug acts upon the 5-HT3 receptor, which is a subtype of the serotonin receptor, located at the terminals of the vegus nerve and in certain areas of the brain. The serotonin (5-HT3) receptor antagonists aid in…
Download file to see previous pages...
Q2 (ii): When testing the agonist action of the morphine-like drugs, it is observable that, through the depressant action of the morphine-like drugs, it was difficult to assess the potencies because the tachyphylaxis developed rapidly. In this case, it is important to use small doses of the drug while exposing the gut to the drugs at the intervals that do not go below 30 minutes. The inhibitory effect of morphine on the twitch of longitudinal muscle was induced by the coaxial stimulation, hence leading to the dose-response curve of order ●. Upon sing nalorphine-like drugs, the depressant action of the N-allyl analogue of the morphine was having the similar order to that of morphine. However, tachyphylaxis development was much more rapid with nalorphine than with morphine.
When testing the antagonist action of the morphine-like drugs, tachyphylaxis was able to develop with all compounds tested, which was a strong indication on the possibility of exhibiting antagonist action under suitable conditions. In this experiment, techyphylaxix was able to develop more rapidly than compared to using the agonist. Basing on the agonist activity of the antagonists, the conventional method used for testing antagonism did not yield the decisive results. The antagonism through low concentrations of morphine of the inhibitory effect of morphine upon twitch of the longitudinal muscle was able to induce coaxial stimulation.
Q3: Through using the experimental protocol or two log curves, there is a possibility of an error occurring. To avoid such errors, the formula can be modified into that of the critical ratio approach (CR). The CR is the concentration of agonist at the presence of the antagonist required for producing a fixed response to the linear part of the concentration. It is thus advisable to use the equation that relates CR to KB, which is expressed
...Download file to see next pagesRead More
Cite this document
(“THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM Lab Report”, n.d.)
Retrieved from https://studentshare.org/biology/1681992-the-actions-of-drugs-on-the-guinea-pig-isolated-ileum
(THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM Lab Report)
“THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM Lab Report”, n.d. https://studentshare.org/biology/1681992-the-actions-of-drugs-on-the-guinea-pig-isolated-ileum.
A basic concept in cellular respiration is the transfer of chemical energy (electrons) from an electron donor to an electron acceptor. Most of the organisms use oxygen as the final electron acceptor although some organisms (eg. Yeast) use other alternatives.
Culturing was both on agar and broth media incubated at 37 o c and 25 o c. The biochemical tests were: Glucose fermentation, sucrose fermentation, Lactose fermentation, Maltose fermentation, Starch hydrolysis, Citrate utilization, Catalase test, Tryptophan digestion (Indole).The most probable bacteria were Bacillus spp which includes C.Tetani, C.
Using this model, we aim to understand the extent of change in the GI tract microbial count of streptozotocin injected diabetic rats compared to in normal rats based on a comparative assay of their glucose content, lactate content and the ratio of the GI tract to the body weights.
These drugs, as their classification is named, works as anti inflammatory meaning it reduces inflammation. Non-steroidal anti inflammatory drugs or NSAIDs are said to be the most prescribed medications for treating arthritis. These aren't merely pain relievers alone but they also have the characteristics of anti-inflammatory which help reduce the inflammation and they also have anti-pyretic characteristics which help reduce fever.
It should clarify processes and procedures, structures and standards and ensure that new employees have a clear understanding with regard to their legal and ethical responsibilities.The Induction should be time limited (2 months in duration). It is envisaged that the initial 4 weeks would cover external visits and a general introduction to the functioning of the team. The second month would encompass building up a client caseload and taking on more elements of the new post.
I personally take a stand to make drugs legal on the issue, and my thinking goes to reflect the stand made by United States which is captured in this statement ""United States was the creation of men who believed that each man has the right to do what he wants with his own life as long as he does not interfere with his neighbor's pursuit of happiness" (Vidal 385). I totally agree with this view, which guarantees that a person can act and think with freedom until it interferes with someone else's freedom.
The easy availability of drug makes the abuse easy. Even though it is illegal it is easily available. The highly addictive nature of the drug is the major problem.
I was attracted by their color and how they organized themselves in social groups of about 20 females with their offspring and one or more male. They were very interesting on how they solved their social conflicts where the subordinate individual lost to the highest
1 Pages(250 words)Lab Report
GOT A TRICKY QUESTION? RECEIVE AN ANSWER FROM STUDENTS LIKE YOU!
Let us find you another Lab Report on topic THE ACTIONS OF DRUGS ON THE GUINEA-PIG ISOLATED ILEUM for FREE!