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Bioinformatics - Lab Report Example

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A normal person has 46 chromosomes while a person with Down syndrome has 47 chromosomes. This extra chromosome affects the brain and body development. Down syndrome is very common and is the cause of many…
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Download file to see previous pages After conducting a blast p search, I chose the following proteins EFR29682.1 a hypothetical protein from Anopheles darlingi it had an E value of 10. This protein is not in any way related to Down syndrome. This is a protein from mosquito saliva and matches by chance. This E value is high; its significance is low in relation to Down syndrome (Pevsner 7).
Protein 2 is EGW12244.1 known as Down syndrome critical region protein 3–like from Chinese hamster (Cricetulus griseus). This protein has an E value of 1 and is related to Down syndrome since the E value is very low. The hamster genome is similar to the human genome (Pevsner 15).
Protein 3 was XP_002122877 with an E value of 0.4 it is a protein predicted to be similar to Down syndrome critical region protein 3 (Down syndrome critical region protein A). It is a protein from Ciona intestinalis, an invertebrate that is closest to humans and shares 80 % of the genome. It has very high significance in the study of Down ...Download file to see next pagesRead More
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