Bioinformatics research - Dissertation Example

Bioinformatics deals with data management in genomics and proteomics of all life forms. It is now accepted as a separate discipline in the main stream biology. Bioinformatics helps researchers worldwide to access various databases for research and to exchange information for comparison, prediction, storage and analysis. As on date, there are a number of databases specific to human, animals, plants and microbes. Bioinformatics accelerated the process of novel drug discovery and development drastically.

In this present study bioinformatics tools and databases are used to find out novel genes and regulatory elements in regions in the nucleotide sequences with relevance towards glucose metabolism. The model generated from the experimentally verified data for transcription factors assist in the prediction of a specific transcription factors. Aspergillus nidulans is a fast growing, true filamentous fungi that belongs to the Ascomycetes family. It normally grows on a defined medium containing yeast extract and glucose serving as primary nitrogen and carbon sources respectively.

The optimum growth temperature for the growth A.nidulans is 370C with good aeration. It doubles at every 1.5hr. A. nidulans is a homothallic, muticellular, haploid, spore former. It is capable of forming both sexual and asexual spores. The spherical conidiophore bears the uninucleate asexual spores called the conidia, which appear rough and range between 3-4 µm, these conidiophores are short and appear brown in colour.