Although the compound is important for health, it poses a health challenge whenever it exceeds optimal levels. Cholesterol levels significantly influence the probability of getting heart problems. Cholesterol has…
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Therefore, it is not easy for anyone to know whether they are in danger or not. As a matter of caution, people are advised to have their cholesterol levels assessed regularly. These checks are conducted through ‘lipoprotein profile’ blood tests (National Cholesterol Education Program, 2005).
The total level of cholesterol is significant in determining the risk of CHD in any individual. The total cholesterol level is computed by adding bad (LDL cholesterol), good cholesterol (HDL) and triglycerides. The difference between LDL and HDL is that LDL contributes to the build up and blockage of arteries, whereas; HDL prevents cholesterol build within arteries. Comprehensive assessment of cholesterol levels requires a lipoprotein profile test. However, where this is not possible one can still get a general idea on the probable level of their cholesterol and risk level. Cholesterol measures are done in milligrams (mg) per deciliter of blood (dL), and any levels above 200mg/dL or below 40mg/dL require that a lipoprotein profile be conducted (National Cholesterol Education Program, 2005).
The levels of HDL should be preferably higher (at least 60 mg/dL) because of the positive role of protecting against CHD. However, levels below 40 mg/dL should be worrying because this level is below minimum and could be a risk because it increases chances of CHD (National Cholesterol Education Program, 2005).
The risk of getting CHD is determined by multiple factors including cholesterol levels, lifestyle and pre-existent conditions such as diabetes (National Cholesterol Education Program, 2005). The risk of developing CHD is determined by considering the risk factors, which are scored against the scale established in the Framingham Risk Score (FRS). The FRS is made up of a number of scoring systems for determining the probability of an individual to get CHD.
The first step entails assessing the number of risk factors that an individual possesses. Each
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The total cholesterol, triglycerides and LDL-cholesterol levels of serum were significantly high (p=<0.01) in test group as compared to control group. The mean level of HDL –cholesterol was found to be significantly low in the test group compared to that of the control group (P=<0.01).
One of the most prevalent group of diseases throughout the world nowadays is cardiovascular diseases (CVD) (Willer, et al., 2008, p. 161), which not only contribute towards significant morbidity and mortality but also incur significant healthcare related costs.
The pathophysiology of the disease is largely credited to insulin opposition with extreme instability of fatty acids incriminated. This assemblage of metabolic uproars and risk factors associated with cardiovascular disease were identified in 1920’s. In the past two decades, there has been an increase in cases of metabolic syndrome due to rising cases of obesity and diabetes (Codario, 2011).
This is a report about a patient with high likelihood of developing cardiovascular problems. It was aimed at determining her cholesterol levels. Cholesterol when in excess causes different health problems, one of which is myocardial infarction. She is 40 years of age, has very close family members who died of heart attacks and diseases, and experienced a mild heart attack recently.
ECG is the primary diagnostic tool which is nearly 100% specific but sensitivity is only63-82%. Gold standard of investigation for detecting Acute Myocardial Infarction is CK-MB; Cardiac specific Troponin can be added to this for better results.
This paper discusses the guideline for the high-risk and very-high risk category together with the researches that support the guideline.
Factors considered when assigning a patient to a risk category include "cholesterol levels, smoking, excessive weight, lack of exercise, high blood pressure and type-2 diabetes" (Barrett, 2006).
This drug (Statin) is potent in reducing cholesterol.
Statin is a generic name derived from 3-hydrooxy-3-methylglutaryl-coenzyme-A reductase (Reamy, 2009). The most significant trials for testing statin against
In this case, bromine, which acts as an electrophilic compound, is attacked by nucleophile cholesterol to form insoluble dibromocholesterol that precipitates. However, to reestablish the double bonds, zinc dusts are used, which removes the bromine atoms from the
Recently there have been efforts to develop drugs that can lower cholesterol levels which have resulted in drugs such as statins and fibrates (Nissen et al., 2005). Statin has been shown to work by reducing the levels of
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