Case Study and review on metabolic abnormalities in early psychosis Name: Institution: Date: Abstract Psychosis and other related conditions have been treated by typical and atypical antipsychotics for a long time…
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These side-effects pose a challenge because of the extra risk that they bring in as well as the possible non-compliance to prescription that may result when patients fear to take the medications because of their associated effects. The review looks at various research articles that seek to understand the effect of antipsychotics in order to understand their relative effects and possible side-effects. The article reviews are also used in making decisions with regard to a case study of a patient under first-episode psychosis treatment using atypical antipsychotics and already showing side-effects. Introduction Psychosis treatment has relied on antipsychotics for a very long time. The first generation antipsychotics (FGAs) fell out of favoured use due to less effectiveness and a number of associated side-effects. They were replaced by second generation antipsychotics (SGAs), which are more effective. The FGAs were linked to a number of side-effects including extrapyramidal reactions such as akathasia, tachycardia, tardive dyskinesia, impotence and seizures among many other. These side-effects have necessitated the use of other drugs such as anticholinergics in order to handle the resultant side-effects such as motor side effects. ...
A number of researches have been conducted to determine the effects of atypical antipsychotics on abnormalities in lipid and glucose metabolism as well as weight gain, otherwise known as metabolic syndrome (MetS). The MetS denotes a combination of increased waist circumference and any of the following two abnormal conditions-a low high density lipoprotein level, hypertension, and high levels of serum triglycerides and/or fasting blood glucose. The fact that both generations of drugs present various side-effects poses greater challenge for practitioners trying to make decisions on which medication to apply in FPP cases. The dilemma on typical versus atypical antipsychotics; as well as whether to use atypical psychotics in FEP considering their potentially negative effects on diabetes and cardiovascular conditions makes this an interesting choice for review. The case study and articles’ review specifically reviews three research articles in relation to the case study in question. The first article reviews the development of metabolic abnormalities as a result of atypical antipsychotics on patients receiving these drugs for FEP through a cross sectional, naturalistic retrospective study. The article’s objective is to develop recognition of the impact of atypical antipsychotics in developing metabolic abnormalities in young patients under FEP treatment. The second article examines results from a naturalistic and prospective study in which the effects of antipsychotic drugs on the development of MetS are monitored through the measurement of weight and serum levels of insulin, glucose and lipids. The third article delves into the issue of providing evidence that can support or discredit the
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