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Patients must be carefully selected for this procedure. The patient must be healthy, available for follow-up visits, and able to follow post-operative instructions. Patients must also demonstrate that oral hygiene is a part of their regular lifestyle. Furthermore, suitable candidates must have a recipient tooth and a donor tooth to undergo the procedure. Patients’ cooperation and understanding are of utmost importance for predictable results (Clokie et al, 2001).
Autogenous tooth transplantation is usually done because of tooth loss due to dental caries, mainly in the first molar of the lower jaws. “Transplantation can also be opted in cases like tooth agenesis (premolars and lateral incisors), traumatic tooth loss, canine atopic eruption, root resorption (body of the cells attack and destroy a part of a tooth), large endodontic lesions, cervical root fractures, and localized juvenile periodontitis” (dentalcareadvice, 2010).
The above pictures (by kunni dental office) demonstrate the removal of the third molar (the wisdom tooth) that is transplanted to the site of the first molar which is beyond repair. The site must be prepared well to receive the donor tooth. There must be sufficient space and alveolar bone structure to accommodate and support the donor tooth. Teeth with poor shape and root morphology are not used in transplants (dental care advice, 2010).
The success of the procedure depends on how well healing takes place after the transplantation. Normally, the tooth with a healthy periodontal ligament provides a higher degree of success. Tooth length and development stage are also important factors in determining the success of the procedure. There is less chance of necrosis (cell death) and higher chance of pulp survival when the premolar has already completed half to two third root development. Placement of implant supported prosthesis or other type
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The clinical and experimental transplantation was extensively exploited in the early 1950s and the first two decades of the 20th century. Joseph Murray and colleagues performed the first successful renal transplant in 1954 at Boston, USA. With no effective immunosuppressant therapies, Murray was aware that tissue rejection would complicate matters for the recipient; therefore in order to minimize the chances of rejection Murray performed the transplantation between monozygotic twins.
Such reality points to the question of procurement. What is it that we are doing to acquire the organs needed by these patients Over the years, legislators and medical professionals have been striving to come up with an organ procurement program that will, at the very least, increase the rate of organ donation the world over.
Before we get into the details of stem cell research, it is important to understand to basics of stem cells and why there are controversies in this field. The basic unit of stem cell research is the cell itself. A stem cell is a kind of cell that has the potential to divide or multiply indefinitely in culture.
Toxins and other harmful substances, come from various sources such as the environment (in the air, water and other environmental factors), from our food especially those laced with high amounts of preservatives and artificial flavours, from the liquids that we drink such as alcoholic drinks and liquid medicinal preparations, and from imbibed poisons taken in accidentally or intentionally.
which give rise to different cell types but not a whole organism; and multipotent stem cells, being much more differentiated cells, can give rise to a limited number of multiple tissue types (Australian Academy of Science, 2001). The haematopoietic stem cells (HSCs) represent
The present study focuses on understanding of the process of graft rejection in transplantation.
Graft rejection in human bodies may be classified as hyperacute rejection, acute rejection or chronic rejection. Hyperacute rejection that is
In addition, when a person is young, they only have 20 teeth, which are later replaced by 32 teeth when they attain adulthood (Kumar 1-2). With respect to function, teeth morphology has functions that include
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