StudentShare
Contact Us
Sign In / Sign Up for FREE
Search
Go to advanced search...

Hemophilia Disease - Essay Example

Cite this document
Summary
Hemophilia is an X-linked hereditary disorder. The disease is characterized by spontaneous or injury-related bleeding. Hemophilia comes in two types, A and B. Both types are the result of gene defects. Hemophilia A is a deficiency of factor VIII occurring in 1 in 10,000 people while Hemophilia B is a deficiency of factor IX occurring in 1 in 40,000.
Download full paper File format: .doc, available for editing
GRAB THE BEST PAPER97.9% of users find it useful
Hemophilia Disease
Read Text Preview

Extract of sample "Hemophilia Disease"

Download file to see previous pages

The oral condition of the human being is characterized by episodes of tooth loss and damage of the gums which leads to bleeding. Keeping the gums and the teeth healthy usually requires procedures that are invasive ( prone to injury). One can just imagine the gravity of the situation to people with hemophilia. That is why one can find numerous studies and researches about the People with hemophilia or congenital bleeding tendencies are a priority group for dental and oral health care, since bleeding after dental treatment may cause severe or even fatal complications.

Maintenance of a healthy mouth and prevention of dental problems is of great importance, not only to quality of life and nutrition but also to avoid the dangers of surgery. . Plaque accumulation causes inflammation of the gums (gingivitis) due to the action of bacteria. This may progress to the damage of the attachment of the teeth to the jawbone (periodontal membrane) resulting to inflammation and damage to this membrane (chronic periodontitis). Ultimately, this leads to the loosening of a tooth and then tooth loss.

With the plaque allowed to calcify, tartar develops above and/or below the gum-line making further accretion of plaque result to Fig 2. The Parts of A Tooth Gingivitis is painless but leads to the . Thru the process of prophylaxis or cleaning of the teeth and gums by the doctor, gingivitis can be prevented thereby limiting bleeding of the gums and eliminating the need for surgery. This can be seen as a pro-active step rather than waiting for the gums to bleed and make use of factor concentrates to stop the bleeding.

The treatment of hemophilia has been undergoing significant innovations since the development of factor VIII concentrates. The current trend of thinking is that prophylaxis is a beneficial therapy for patients with hemophilia A as compared to on-demand treatment. The observed benefits include reduced number of bleeding episodes, improved joint function and a relatively healthier patient. Hoots et al reviewed the literature about the topic and weighed the value of these benefits against the increased expense due to increased factor use.

(Hoots et al, 2006)How Is Dental Surgery Performed To A HemophiliacPerforming dental surgery on a hemophiliac patient, even for a simple dental extraction, must be thoroughly planned such that the risk of bleeding, hematoma formation or excessive bruising is minimized. To prevent any problems or complications, the two following points must be realized:Rarely will emergency dental surgical intervention be required as control of pain can be registered without resorting to an unplanned treatment.

Discussions with Hemophilia patients requiring prophylactic cover concerning the treatment plans must be doneFor those suffering from severe hemophilia, factor replacement is a necessary pre-surgery procedure along with regional block injections or scaling. Those suffering from hemophilia A usually require a dose of 50 iu/kg of factor VIII and a dose of 100 iu/kg of factor IX in hemophilia

...Download file to see next pages Read More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 words”, n.d.)
Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 words. Retrieved from https://studentshare.org/miscellaneous/1508598-hemophilia-disease
(Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 Words)
Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 Words. https://studentshare.org/miscellaneous/1508598-hemophilia-disease.
“Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 Words”, n.d. https://studentshare.org/miscellaneous/1508598-hemophilia-disease.
  • Cited: 0 times

CHECK THESE SAMPLES OF Hemophilia Disease

Critical review on The Haemophilias

hellip; Depending on the type of coagulation factor involved, Haemophilias can be of two types, namely haemophilia A (true haemophilia or Classical haemophilia), which is associated with defective production of factor VIII and Haemophilia B (Christmas disease or Plasma Thromboplastin Component Deficiency), which is associated with defective production of factor IX (Hoffbrand et al, 2006). mutations in the gene encoding blood coagulation factors VIII or IX respectively (Turgeon, 2004)....
5 Pages (1250 words) Essay

The use of gene therapy to treat genetic diseases

On the other hand, if both the copies carry sickle cell beta globin gene then the individual has sickle cell anemia and suffers from the debilitating disease.... Hemophilia is a recessive, X linked disease; therefore, genetic segregation and dominance play an important role in the inheritance of hemophilia.... Therefore, the disease is more common in males because they have a single X chromosome and if it has the mutated gene then the person will have hemophilia as unlike females they do not have another X chromosome for compensation....
4 Pages (1000 words) Essay

Summarising

Prior treatment, the mouse depicted no levels of clotting factor IX since previous studies by different researchers shown that ZFNs could accomplish genome editing if injected into mice for sickle cell disease treatment.... Since different mutations in the same gene may cause hemophilia, the process replaced seven different coding sequences, covering 95% of the disease-carrying mutations in hemophilia B.... at The Children's Hospital of Philadelphia, the research established that genome editing could correct a genetic defect in vivo Genome Scientists have achieved clinically meaningful results by treating hemophilia in mice using genome editing....
2 Pages (500 words) Assignment

Technology Advancements and Stem Cells Research in Hemophilia Treatment

Stem cells have several pros and, therefore, this paper "Technology Advancements and Stem Cells Research in hemophilia Treatment" will extensively shed light upon the various uses of stem cells.... What changes has it brought to the cure of hemophilia will also be examined in this paper.... Stem cell research is particularly useful for patients suffering from hemophilia.... “Mouse embryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a form of hemophilia in mice analogous to hemophilia B in humans, the new study shows....
4 Pages (1000 words) Research Paper

Haemophillia type A genetic disease

So, a genetic disease refers to a disorder or illness that is caused by one or multiple defects and abnormalities present in the genome.... On the other hand, the inherited genetic conditions in some people may be the reason for the occurrence of same disease, such as a particular type of cancer (Kuliev, Verlinsky, p.... They help in building… This paper will discuss the genetic disorder in general and hemophilia type A in particular.... The inherited deficiencies of coagulation factors include hemophilia A and B, also known as...
6 Pages (1500 words) Essay

Case study exam

Hemophilia Disease associated with deficiency in blood clotting factor VII is sex linked and therefore carried by the sex genes whereas DM is an autosomal dominant gene and not sex linked.... The genetic disease DM and one causing blood clotting factor VII have the pattern of inheritance identified in question 2.... Second what does it mean that DM is an autosomal dominant disease?... Both Kyle and Sean were unable to suffer from the disease since the hemophiliac receive gene is often carried in the X chromosome....
4 Pages (1000 words) Assignment

Hemophilia as a Genetically Inherited Bleeding Disorder

The author outlines Hemophilia A as an X-linked recessive disease which is characteristically a bleeding disorder due to deficiency of the coagulation factor VIII.... Dominant diseases are those in which the disease is expressed in the homozygous or heterozygous condition and recessive conditions are those in which the disease is expressed only in homozygous condition (Yashon & Cummings, 2009).... This work called "hemophilia A" focuses on the various types of mutations that lead to alterations in the normal human genome....
7 Pages (1750 words) Essay

Genetic Diseases: Hemophilia A

This work called "Genetic Diseases: hemophilia A" describes illnesses caused by a single or more form of abnormalities in the human genome.... s Bowen (2002) provides, hemophilia A is a genetic disorder, which is primarily caused by the deficiency in factor VIII, essential for clotting, quick, and timely wound recovery....
6 Pages (1500 words) Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Contact Us