Deficiency in blood clotting factor VIII results to hemophilia that is a condition mostly characterized by uncontrolled bleeding and which can be treated by regular injection of factor VIII (Haines, 21)…
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The father is normal. Greg’s sister is carrier. Greg’s aunt has DM and is married to an unaffected man. Greg’s mother is both a DM carrier as well as a hemophiliac carrier. There are third chances that Greg may be a carrier for DM (Love, 391).
You must provide names for each member if they are known. I don’t know who you are referring to in the paragraph above. Please label each circle and square represented with name of the individuals that are described in the family history Greg and Olga.
Olga’s maternal grandmother is a carrier while her sister was hemophiliac. Olga’s mother is a hemophiliac carrier whereas the uncle is hemophiliac. The hemophiliac gene was carried from the mother to Olga. Olga is therefore a hemophiliac carrier with Frank being a hemophiliac and the other brother being normal.
The genetic disease DM and one causing blood clotting factor VII have the pattern of inheritance identified in question 2. Hemophilia disease associated with deficiency in blood clotting factor VII is sex linked and therefore carried by the sex genes whereas DM is an autosomal dominant gene and not sex linked.
I disagree. First, not all of these people carry the gene for DM. Second what does it mean that DM is an autosomal dominant disease? If you look at the description, Angie is not affected by DM and only one of the uncles (Ernie, or Al) is affected by DM. Go back and review the idea of autosomal dominant diseases and revise these genotypes accordinglhy.
Both Kyle and Sean were unable to suffer from the disease since the hemophiliac receive gene is often carried in the X chromosome. The two boys inherited their X chromosome from their mother who was normal and their Y chromosome from their father who was hemophiliac. Hemophiliac recessive gene is never carried in the Y chromosome. I agree
Frank inherited his X chromosome from the mother and a Y chromosome from
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