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Behavioral Pharmacology Lab Experiment - Article Example

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The aim of the essay assesses the how the two compounds brought about an amplification of the innate fears and exploratory behavior in rats. This laboratory experiment focuses on various compounds’ effects to animal behavior. The two chemical compounds used were Lithium Chloride and Sodium chloride.  …
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Behavioral Pharmacology Lab Experiment
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Download file to see previous pages Lithium stands as a drug of choice in the treatment of psychological disorders. The drug is mostly applied in bipolar disorders such as acute mania. Other such disorders include diverse syndromes that tend to be characterized by recurrent, as well as, episodic symptoms (Sproule, 2009). The pharmacological mode of action of Lithium has been studied extensively using various models in the laboratory. Some of the methods look at the psychomotor activation, spontaneous activity, and many other activities that are dependent on the motor portion of the nervous system.
The behavioral pharmacology test conducted was aimed at observing the effectiveness of Lithium chloride on the various specimens used and their response. The experiment used Lithium Chloride as the main ingredient and sodium chloride as the control solution. The main objective of the experiment was an observation of the effects of taking against not taking Lithium chloride and, on the other hand, taking sodium chloride. We used an open field apparatus from whence we could observe the behavior of the rat immediately after the injection with the drug. Hypothetically, the compound normally modifies the exploratory behavior, innate fears, and locomotive behaviors of rats and mice. The experiment was carried out to observe the truthfulness and effectiveness of the above-mentioned objectives.
An open field apparatus was used to observe the effects of the drug on the rats. An Open Field Apparatus is a (4’x4’) enclosed box. The box has a viewing pane and requires one to place the rat on one side of the box as he or she monitors the movement of the rat inside the apparatus for a predetermined period of time. The rats were administered with 1% lithium chloride or sodium chloride solution an 85mgs/kg intraperitoneally (I.P) an hour (exactly) before the open field was performed.   ...Download file to see next pages Read More
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