Contact Us
Sign In / Sign Up for FREE
Go to advanced search...

The Controversial Use of Apligraf in the Treatment of Diabetic Foot Ulcers - Research Paper Example

Comments (0) Cite this document
The author concludes that despite disputes whether effective in the long term, diabetic foot ulcers, as evidence from the literature suggests can now be effectively treated by tissue-engineered skin grafts since they provide growth factors, promote vascularization in a chronic nonhealing wound…
Download full paper File format: .doc, available for editing
GRAB THE BEST PAPER91.5% of users find it useful
The Controversial Use of Apligraf in the Treatment of Diabetic Foot Ulcers
Read Text Preview

Extract of sample "The Controversial Use of Apligraf in the Treatment of Diabetic Foot Ulcers"

Download file to see previous pages Foot complications are major causes of hospital admissions for diabetes, and they often demand surgical procedures and prolonged length of stay. Indeed, diabetic foot complications are major global public health problems in that these foot lesions and amputations represent the most important of all long-term problems associated with the disease of diabetes and have medical, social, and economic implications. Three great pathologies come together in the diabetic foot: neuropathy, ischemia, and infection. Their combined impact is so great that it causes more amputations than any other lower limb disease. As diabetic foot problems quickly reach the point of no return, it is vital to diagnose them early and provide rapid and intensive treatment. Furthermore, it is important to achieve early recognition of the at-risk foot so as to institute prompt preventive measures. The late sequelae of diabetic peripheral neuropathy are recognized to be foot ulceration and Charcot’s neuroarthropathy. It has been the fact that the risk of developing foot ulceration as a result of end-stage complications of neuropathy and vascular disease in diabetes is much greater than the other end-stage sequelae of diabetes, namely, retinopathy and nephropathy. The prevalence of foot ulceration in the general diabetic population is 4–10%, being lower in young and the highest in older patients. The lifetime risk for foot ulcers in diabetic patients is about 15%. Rothman’s model of causation defines a combination of neuropathy, trauma, and foot deformity to be the commonest pathways to foot ulceration and faulty healing may eventually lead to amputation. Foot ulceration and amputation affect the quality of life for patients and create an economic burden for both the patient and the health care system. Therefore, efforts to identify the patient who is at risk for foot ulceration, prevention, and appropriate treatment must, of necessity, become a major priority for healthcare providers. Peripheral neuropathy and vascular disease alone do not cause foot ulceration. ...Download file to see next pages Read More
Cite this document
  • APA
  • MLA
(The Controversial Use of Apligraf in the Treatment of Diabetic Foot Research Paper, n.d.)
The Controversial Use of Apligraf in the Treatment of Diabetic Foot Research Paper. Retrieved from
(The Controversial Use of Apligraf in the Treatment of Diabetic Foot Research Paper)
The Controversial Use of Apligraf in the Treatment of Diabetic Foot Research Paper.
“The Controversial Use of Apligraf in the Treatment of Diabetic Foot Research Paper”, n.d.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF The Controversial Use of Apligraf in the Treatment of Diabetic Foot Ulcers

Diabetic Foot Ulcer Infection Prevention

...). The Cochrane Collaboration, 1-50. European Wound Management Association (EWMA). (2010). Outcomes in controlled and comparative studies on nonhealing wounds: recommendations to improve the quality of evidence in wound management. Journal of Wound Care, 19(6), 239-268. Faglia, E., Mantero, M., C. M., Caravaggi, C., De Giglio, R., Pritelli, C., . . . Graziani, L. (2002). Extensive use of peripheral angioplasty, particularly infrapopliteal, in the treatment of ischaemic diabetic foot ulcers: clinical results of a multicentric study of 221 consecutive diabetic subjects. Journal of Internal Medicine, 252, 225–232. Gershater, M., Pilhammar, E., Apelqvist, J., & Alm-Roijer, C. (2011). Patient education for the prevention of diabetic foot ulcers...
5 Pages (1250 words) Essay

Diabetic Foot Treatment

This in turn helped me to gather information and helped me in my research work.
Podiatrist at Diabetic Foot Clinic, Orsett.
Stephen King MChS Chief Podiatrist.
Sandra Warn MChS Senior Podiatrist
Wendy Bristow MChS Senior Podiatrist.
Specialist Group of Podiatrist who taught me the debridement of foot ulcer and care of the charcot foot.
Dr John Tuppen PECK Chair, BBW PCT supported my application for doing the Masters in Diabetic Foot Care.
Dr. Mira Varagunam Ph D Statistician helped me in going through the statistical analysis meticulously and with a great deal of patience. Her valuable and timely advice helped me to compile the statistical analysis,
Basildon PGC Library
Middlesex University Library...
50 Pages (12500 words) Dissertation

Diabetic Foot Ulcers in a Smoker Patient

This research will begin with the statement that diabetic foot is one of the common yet preventable complications of diabetes that shows the increased risk of development because of the presence of certain risk factors. These risk factors include smoking as the highest contributing factor, due to the negative effect on the vascularity of the body. Identification and proper prevention and treatment are essential for the prevention of diabetic foot. Also, routine checkups and awareness programs are needed in order to prevent such rates from increasing. There is an expected increase in the future cases of diabetes around the world and concomitantly the complications associated with diabetes. This makes the prevention of further ca...

11 Pages (2750 words) Assignment

Are silver dressings helping in the treatment of diabetic foot ulcers

In spite of the progress made over the decades in the understanding and treatment of these complex chronic wounds, most wounds do not respond to conventional treatments.
Silver has been used for centuries in the treatment of wounds. The antimicrobial properties of silver are well documented since ancient times. Even as early as 750AD, silver vessels were used to store water in recognition of silver’s medicinal properties. Crede is credited for producing the first scientific papers in 1881, on the use of silver for preventing eye infection in neonates. In 1965, Moyer et al reported on the antibacterial action of 0.5% silver nitrate compresses applied to extensive burns (Maillard, 2006).
Commonly used vehicles for delive...
18 Pages (4500 words) Essay


... or a CD containing this data. If the MRI has wireless network connectivity options, it has the potential to stay more useful over time and improve delivery of services to the patient. In conclusion, better planning, having the right information and making the optimum choices, it is possible to tilt the balance in favor of benefits in the cost/benefit equation without incurring very high incremental costs. Works Cited “How Common: The Key to Cure”. Centre for Disease Control. 28 Sep 2006. 6 Sep 2007. ulcer/keytocure.htm#howcommon> “Illnesses: The Key to Cure”. Centre for Disease Control. 28 Sep 2006. 6 Sep 2007. ulcer/keytocure.htm#illness> “History of Ulcer Diagnosis and Treatment”. Centre...
13 Pages (3250 words) Research Paper

Treatments of Diabetic Foot Ulcers: Debridement

The researcher will begin with the statement that his current involvement is with a diabetic unit in a Saudi Arabia hospital. In this unit, the following are being applied: optimal diabetic control, appropriate wound management, management of ischemia, management of infection, debridement, and pressure relief. The topic of the treatment or debridement of diabetic foot ulcers was chosen because it is one of the most persistent issues for diabetic patients. The researcher chooses Saudi Arabia because diabetic foot ulcers are a major issue for them. Knowing how to manage it can help improve the quality of life of patients. A recent study by Tashkandi,, indicates that diabetes has become a common issue in Saudi Arabia and ab...

6 Pages (1500 words) Essay


... important. The people afflicted with the disease have no option but to live to their best with thin condition, since the lack of a definitive cure cannot be reversed. The two parts of the theory, stress and coping are described differently for different individuals. Type-2 diabetes is an increasingly prevalent disease in the world and research indicates that though the complications and symptoms of the disease are recognized, treatment has remained a challenge. The main problem with diabetes treatment is that the patient will have to adjust to new diets, complicated treatment strategies and cost problems in treatment. The main treatment strategy for diabetes is use of insulin regimens, and the main chronic disease self management practice...
12 Pages (3000 words) Essay

The Lived Experience of Type II Diabetic Patients with Foot Ulcers - A Descriptive Phenomenological Approach

The complications developing in the foot could end up in the amputation of the foot due to the foot ulcers. Advances are observed in the in diagnosing and identifying these problems, but the advances in the treatment remain relatively poor. In this research proposal, the steps by which the descriptive phenomenological study will be undertaken to find out the lived experience of type II diabetic patients with diabetic foot ulcers is provided. A discussion of these relevant steps taken for the conduct of the study is undertaken. In addition, the reasons for selecting the chosen methodology and the relevance of the research are also provided.
Evaluation of the frequency of hospitalization due to diabetic complications demonstrates...
26 Pages (6500 words) Research Paper

Diabetic Foot Ulcers

... used will be to enter a multiple key word search in ebsco host and Ovid, as well as medline. Included in the multiple key word searches will be diabetic ulcer, forefoot, rearfoot, offloading, hydrocolloids, and other words suggested in the review. Those articles found will be categorized in background, information about the diabetic ulcer, prevention methods, and then treatment methods. Those articles found not to be peer reviewed will be eliminated. Literature Review Schaper, Prompers, and Huijberts, (2007) provide the reader with a good background understanding of the diabetic foot ulcer, general methods of diagnosis and treatment. Covered in this article are epidemiology and costs as well as general pathways to ulceration...
9 Pages (2250 words) Literature review

Management of Diabetic Foot Ulcers

... way to guarantee success by reducing number of lower-leg amputations emanating from diabetic foot ulcers is through the use of best practices in wound management as a whole. Review of relevant scientific evidence in previous literature There are a number of studies that have been taken to focus on the chronology of treatment and care of diabetic foot ulcer. In one such study by Vyas and Vasconez (2014), the history of diabetic foot ulcer was related to the overall history of wound care where it was found that management of wound can be traced as far back to prehistory era before modern medicine. Before modern medicine, Scott (2013) indicated that most of the approach to wound care was through natural healing. This means that no special...
6 Pages (1500 words) Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Research Paper on topic The Controversial Use of Apligraf in the Treatment of Diabetic Foot Ulcers for FREE!

Contact Us