Nobody downloaded yet

Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood - Essay Example

Comments (0) Cite this document
Summary
Evans et al (2010) sought to find out if the incipient fractal dimension Df of a clot, could serve as functional biomarker in the process of hemostasis. The focus of this study…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER97.6% of users find it useful
Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood
Read TextPreview

Extract of sample "Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood"

Download file to see previous pages This way, the study aimed at investigating the value of dimension Df that characterized incipient clots formed in unadulterated blood samples, which were extracted from healthy participants. This was with a view to establish a “healthy index” which was to be used in representing a value of an incipient clot microstructure in terms of fractal dimension, and to further manipulate a healthy blood using unfractionated heparin. It also aimed at comparing any change in Df against standard thromboelastography (TEG) and laboratory coagulation markers.
The subjects were divided into two groups: the healthy group and the Anticoagulant group. For the healthy group, strict exclusion criteria ensures healthy volunteers who were on antiplatelet or anticoagulant therapy, and those with a family or personal history of thromboembolic disease, and any acute disease, hepatic, renal dysfunction, or cancer were eliminated. This group consisted of 23 women, and 29 men totalling to 52 healthy patients. The mean age for the subject of this group was 33.6 years. On the other hand, the anticoagulant group had 38 healthy adults: 13 women, 25 men, and a mean age 25.2 years.
In studying the impact of inhibiting production of thrombin on an incident clot, volumes (>10 uL) of unfractionated heparin were added to a volume of 20 mL of blood in vitro. The resulted in the production of an effective Antifactor (Xa) concentration ranging from 0.05 to 0.08 IU/mL. To minimize any dilution effect, a small volume of heparin was added to a larger volume of blood. The unfractionated heparin was altered to prolong activated partial thromboplastin to the range corresponding to the 0.3 to 0.7 U/mL of heparin.
For analysis purposes 4 ml aliquots of blood was extracted from a sample for full blood count analysis including a platelet count. Samples were collected into full-draw dipotassiu, ethlenediamitetraacetic acid vacuattes. The Sysmex XE 2100 was used to analyse FBC. In the Rheometry, aliquots ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Gel point and fractal microstructure of incipient blood clots are Essay”, n.d.)
Gel point and fractal microstructure of incipient blood clots are Essay. Retrieved from https://studentshare.org/health-sciences-medicine/1633273-gel-point-and-fractal-microstructure-of-incipient-blood-clots-are-significant-new-markers-of-hemostasis-for-healthy-and-anticoagulated-blood
(Gel Point and Fractal Microstructure of Incipient Blood Clots Are Essay)
Gel Point and Fractal Microstructure of Incipient Blood Clots Are Essay. https://studentshare.org/health-sciences-medicine/1633273-gel-point-and-fractal-microstructure-of-incipient-blood-clots-are-significant-new-markers-of-hemostasis-for-healthy-and-anticoagulated-blood.
“Gel Point and Fractal Microstructure of Incipient Blood Clots Are Essay”, n.d. https://studentshare.org/health-sciences-medicine/1633273-gel-point-and-fractal-microstructure-of-incipient-blood-clots-are-significant-new-markers-of-hemostasis-for-healthy-and-anticoagulated-blood.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood

Blood pressure

.... Patients should always be counseled about the significance of blood pressure particularly the fact that it is required in a normal healthy person. The patient should be asked if he has taken coffee or smoked cigarette because that can lead to a higher measurement. The patient should also be asked to avoid exercise before the measurement as that can lead to a lower reading. At least three readings which are separated in time should be taken in order to determine the blood pressure accurately. One must not rely on a single reading (Longmore 2007). The most commonly used method is the aucultatory method. The patient’s right arm should be raised to the level of the heart if...
2 Pages(500 words)Essay

Blood clotting is an essential and potentially lethal process of life

.... The normal blood clotting system is defensive and is essential, intended to prevent blood loss, a normal process called hemostasis. At other times, the body aggressively over-responds when there is not really a danger of blood loss, a disease process called thrombosis. In heart attacks and strokes, damage inside a blood vessel, often caused by cholesterol deposits, can trigger the same molecular reactions and produce an undesirable clot, called a thrombus. Unlike a normal clot, thrombi cut off essential blood flow to vital organs such as heart, lungs, brain, kidneys etc. It is a...
5 Pages(1250 words)Essay

Blood Diamonds

...the stone.’ “In some African countries, such as the Democratic Republic of Congo tens of thousands of civilians have over the past years been killed or tortured and millions have been displaced” (International Secretariat, 2006). Many came to realize that they not only financed genocide and other acts of vulgar inhumanity by purchasing a diamond but were also wearing and flaunting this symbol of human suffering. The main source of this horrific revelation to the world community was last year’s movie ‘Blood Diamond’ which attempted to alert the masses to the atrocities occurring in Africa. Until then, this situation was largely ignored by Western governments and news media. In one scene of the movie,...
5 Pages(1250 words)Essay

Blood pressure

...are interrupted because of the fear that fatigue and overconsumption of forbidden foods may lead to a more severe health condition. Subjective cues are not reliable and people will always depend on blood pressure checking, with most of the schedule interrupting usual things to do. There is no cure for alterations in blood pressure and people will always bear the pathophysiological symptoms associated Managing Blood Pressure Maintaining healthy blood pressure requires regular schedule for blood pressure screening and consultation from primary care providers about the medications, diet, and exercise regimen needed. In managing...
3 Pages(750 words)Assignment

Blood composition

... Teacher’s Institute BLOOD COMPOSITION Blood is the basic body fluid. It is the fluid that flows through the vessels and maintainsthe circulatory function among the body systems. Blood serves major functions owing to its composition. Blood is composed of plasma and three types of cells: Red cells, white cells and the platelets. Plasma is the fluid part and serves as the transport medium. The cells are formed in the bone marrow from the pluripotent stem cells. These cells are unique as they have the ability to differentiate into any of the hematopoietic cell lineages. They either divide into lymphoid stem cells or myeloid stem cells. The latter are responsible for giving rise to the blood cells. The mixed myeloid progenitor cells... ...
1 Pages(250 words)Essay

Blood substitutes

...April 17, Blood Transfusions and Blood Substitutes: Some Considerations Can you think of other cases where blood substitutes would be useful? Blood substitutes would be highly useful for Jehovah’s Witnesses; soldiers in combat areas and people in disaster and trauma zones or in highly remote areas (where portability of human blood and the challenges of cross-typing are issues); for use with people whose hyperactive immune system may initiate a dangerous allergic reaction, or people whose hypoactive immune systems may not be able to cope with the infection potential; and for people in high HIV or hepatitis risk areas where uncontaminated...
2 Pages(500 words)Essay

Blood Cholesterol/Blood Pressure

...of heart diseases and many diet conscious people have complied with this (Park, 2012). One will be forced to think again, according to the Archives of the International Medicine, the proponent of the idea are taken to have missed a point. The body conducted a research to prove the point but of the 20, 500 patients that were chosen at random and administered omega-3 and placebo developed heart diseases in equal measure (Park, 2012). This new advancement throws into jeopardy the first assertion. They concluded that there must have been biasness in the first research and the role of omega-3 in treating heart disease is still at large. Work Cited Krueger, Pat. "What Is a Relationship Between...
1 Pages(250 words)Assignment

Blood Diamonds

...and the loss of the rise of standards. This leads the Kimberly Process in no ability to make any decision. Thus, this justifies the point that the Kimberly Process is doing so little to stop blood diamonds. The Kimberly Process also cannot solve the problems of violence, human rights abuses and death. This is by the narrow definition of the term conflict diamonds as diamonds that fund rebel groups. Therefore, this organization does not have any authority to stop the suffering of the artisan diamond miners and stop the trade of blood diamonds. Governments have failed to hold the international diamond trade industry to account for the on-going trade in conflict diamonds. This means that...
11 Pages(2750 words)Research Paper

Blood Pressure

...Insert Introduction During the laboratory activity, systolic blood pressure (the maximum pressure exerted by the blood against the artery walls) of the test subject was 110 at rest. However, this pressure increased to 120 and 140 when subject was placed under 1kg and 2.5 kg workloads respectively. This was the case as blood flow has to increase during strenuous activity (exercise) in order to supply nourishment (oxygen and nutrients) to critical organs such as the heart, brain, lungs and muscles. At the same time, diastolic pressure (the lowest pressure in the artery) at rest was measured at 70 but decreased to 50 then 40 at 1 kg and 2.5 kg workloads respectively. Diastolic pressure is a...
1 Pages(250 words)Essay

Blood

...Origins of blood types There are no less than 3 hypotheses regarding the emergence as well as transmutation of human blood types. Human blood types evolution is as old as human history. Worldwide distribution pattern of blood types is dependent on different environmental factors like climate, disease, humidity and altitude. In 1900, Karl Landsteiner made a discovery. According to him, some blood transfusions are successful while others are dangerous missions. Landsteiner also discovered particularly the ABO blood group by mixing some of his cells and mature serum in every one of their staff. He also proved that some people’s red...
2 Pages(500 words)Assignment
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Essay on topic Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood for FREE!

Contact Us