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Cancer Pharmacology - Essay Example

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I would like to take this opportunity to thank almighty God for helping me through this testing time in my life, god willing helping me to move positively forward. Secondly and by far means least, I would like to thank., without his guidance and support this project would not been possible…
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Cancer Pharmacology
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Download file to see previous pages I would also like to acknowledge .. who has given me the encouragement and confidence throughout my year at University. The words thank you do not comprehend the way he has guided me through this year, including the highs and many lows I have encountered.
In addition I am extremely grateful for the assistance, generosity, and advice I received from Hafiz. His encouragement and support throughout the project has been invaluable. As he encouraged me to develop my project and my personal independent thinking skills. He continuously encouraged me stimulate my analytical skills and greatly assisted me in the laboratories and showing me how to put my results together.
This dissertation would not be possible without the fabulous technicians at , without their knowledge and expertise, also not forgetting, how should I put it, there alternative sense of humour, in particular ., and .. you are my stars.
I would also like to thank my Family; Mum Dad and not forgetting my sisters and my brother!! Also my two gorgeous nieces, Komal and Armani who have taken my mind off many a stressful situation and have brought a smile to my face when thinking my final project was a drawing book.
A fully functioning vasculature is important for the delivery of nutrients and removal of toxic metabolic wastes associated with normal cellular metabolism. All normal tissues acquire this immensely intricate vasculature from the blood vessels or circulatory tree in the vicinity. The human circulatory system, apart from these functions, also provide cells that can help immune functions and maintain hemostasis. Human body, although ultimately comprised of cells as the final functional unit, is organised into tissues that are richly supplied by the network of a circulatory system, where the architecture is planned in such a manner that the majority of these about 1013 cells are located almost in close proximity of about less than 100 micron to a feeding or draining blood vessel. This facilitates to and fro movements of substances bilaterally from the cells and blood vessels. Like nutrients, this serves as a significant vehicular pathway for drugs. Although tumor cells originate from the healthy and normal cells, they vary from the normal tissue cells in different counts. The vascular network for a growing tumor is indeed acquired at least in part by the incorporation of existing host blood vessels. Tumor expansion requires ultimately new blood vessels. Thus tumor growth and survival are critically linked to a parallel proliferation of endothelial cells comprising the tumor blood vessel network (Hahnfeldt et al., 1999). The process involved, neovascularization, is relatively uncommon in most normal tissues, but now recognized to be an important feature of solid tumors. These variations mean that the physiology of solid tumors differs from the physiology of normal tissues in a multiplicity of aspects, mostly stemming from the ...Download file to see next pagesRead More
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