Nobody downloaded yet

Bloom syndrome - Essay Example

Comments (0) Cite this document
Bloom syndrome is a genetic disorder that occurs due to the inability to conserve the genomic structure of the body.The mishap in genetics comes because of crossovers of sister chromosomes;the syndrome is brought by autosomal resseciveness of BML gene…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER96.7% of users find it useful
Bloom syndrome
Read TextPreview

Extract of sample
"Bloom syndrome"

Download file to see previous pages Bloom disease predisposes individuals to cancer as it causes pro activity in suppressor cells that alters the division of cells to a hyperactive state (Cox, 2009). This disease is common amongst the Jews; the casualties appear short in stature and are sensitive to sunlight. The study of the journal considered purposed to establish the efficacy of BTB complex in Double Holliday Junction dissolution in prevention of crossovers. Indeed the study shows that dissolution of the DHJ using BTB is possible only with the combination of energy provider, ATP that is hydrolyzed by BLM and the complex mixed with a protein complex, Fanconi ammonia. This article I have to admit that the article embraces all the scientific controls and procedures that were well programmed and followed to ensure that the objective and hypothesis of the study is tracked to produce results that satisfies both validity and reliability. Notwithstanding, the article is short of coherency and unequivocal state of the objectives of the study amongst other oversights. Introduction Bloom disease is one of the rarest diseases that are known today, it is a genetically disease that occurs in a homozygous recessive situation. The disease occurs due to the crossing over of the chromosomes during cell division, i.e. meiosis (Modrich, 2006). During this stage of cell division, fragment of the Deoxyribonucleic Acids (DNA) are realized due to the unwinding nature of the DNA at this stage. These fragments later rejoin randomly leading to alteration of the initial genomic structure and one resultant features is the bloom disease (Modrich, 2006). Specifically, bloom disease due to the changes discussed above occurs due to mutations at the BLM gene (Cohen, 2004). The disease is hereditary and can be passed to the offspring by the parents who are carriers. Bloom disease is known to be responsible for a number of misfortunes in human beings; the disease causes cancers as it makes the regulatory genes in the human body to be hyperactive leading to the uncontrolled proliferation of cells causing cancers (Tropp & Freifelder, 2008). The occurrence of cancers in this case is observed even in young children, this has made the disease to be known for causing old age diseases in children. The individuals with this disease also show a short a stature and may prompt acquisition of other medical conditions like diabetes type II, color change of the skin making the individuals to be vulnerable and sensitive to sunlight, and chronic pulmonary disease (Tropp & Freifelder, 2008). The prevalence of the disease is high amongst the Jews and that for every one hundred Jews, there is an individual with the bloom disease (Modrich, 2006). The article critique has revolved around the bloom disease in the capacity of mitigating the cause and finding the most appropriate item to be used in mitigation efforts. The article identifies the disease and looked at how it occurrence and the factors that accelerate its occurrence. The gene responsible for this disease is identified as BLM. BLM is found in the human genome and is one of the human RecQ genes (Waldman, 2004). RecQ genes are important in the maintenance of genetics in both the prokaryotes and the eukaryotes. In prokaryotes, the RecQ genes are important in ensuring that the structure of the genome is maintained despite the gene recombination that takes place in the bacteria (Waldman, 2004). There are about five RecQ genes in human of which all strive to maintain the originality of the genome in order to arrest erratic gene disruption that may cause genetic disorder of bloom’ ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Bloom syndrome Essay Example | Topics and Well Written Essays - 2000 words”, n.d.)
Retrieved from https://studentshare.org/biology/1435538-bloom-syndrome
(Bloom Syndrome Essay Example | Topics and Well Written Essays - 2000 Words)
“Bloom Syndrome Essay Example | Topics and Well Written Essays - 2000 Words”, n.d. https://studentshare.org/biology/1435538-bloom-syndrome.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
Down syndrome
Studies provide that the severity of Down syndrome disorders might vary from one individual to another. This article is a summary of the causes of Down syndrome. The pattern of prevalence of Down syndrome Medical studies have classified Down syndrome as one of the most prevalent birth defects.
4 Pages(1000 words)Essay
Koro Syndrome
Gentle forms of “out-of-the-body” experiences generally fall within the dissociative disorder categories. In different parts of the world, there have been proofs of various disorders that have been marked as instances of de-personalization, which differs greatly from those typically seen in the West.
10 Pages(2500 words)Essay
Down Syndrome
As humans struggle through the ever increasing myriad of challenges, one thing they have to content with being, that genetic related diseases pose a significant threat to human survival. As such, genetic disorders comprise of various diseases that affect all age groups be it young, or old Genes, (Hindley 67).
21 Pages(5250 words)Essay
Down Syndrome
Down syndrome (DS) is a genetic disorder that hampers the mental and physical development of those afflicted. It results when an individual has an extra 21st chromosome, i.e. a total of 47 chromosomes, rather than the usual 46 chromosomes.
4 Pages(1000 words)Essay
KlverBucy syndrome
In the late 1930s, Paul Bucy and Heinrich Kluver showed that temporal lobe removal, which disrupts the Papez circuit, has profound effects on the social and emotional behaviors of rhesus monkeys.
10 Pages(2500 words)Essay
Asperger Syndrome
Asperger syndrome, which is more prevalent in boys, is rarely diagnosed and often mistaken as high-functioning autism. Because the cause is uncertain, there is no precise remedy for the
18 Pages(4500 words)Essay
Compartment Syndrome
The purpose of this paper therefore is to present the topic of Compartment Syndrome in the clearest and simplest way possible while maintaining to be concise.
6 Pages(1500 words)Essay
Interview with Harold Bloom Blood Meridian
Indeed, the scalping and the tree full of dead babies are some of the shocking portrayed in contemporary American literature. McCarthy’s portrayal of life and death on the America frontier are almost
2 Pages(500 words)Essay
The Bloom Box
I think that the technology is especially viable based on the fact that it produces less carbon dioxide emission in the atmosphere compared to coal powered energy inventions. Additionally, the technology is still undergoing numerous developments
1 Pages(250 words)Essay
The Bloom Box
grid (Saranya 327). Even so, Ker than criticizes it as an overhyped product that is a normal form of technology. In my opinion, the technology used in the Bloom Box is not viable or
1 Pages(250 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Essay on topic Bloom syndrome for FREE!
logo footer
Contact us:
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us