Increasing health care complexities necessitates nursing candidates to be more competitive by gaining deep knowledge in various areas of science. Having great knowledge in humanities and science are essential to promote the concept of culturally competent care and to enhance quality care. Academic literatures also highlight the significance of expertise in science and humanities for achieving greater level of patient safety. This paper will analyze the science and humanities pre-requisites that should be in place for a BSN nursing program. Pre-requisites for a BSN Nursing Program Bachelor of Science in Nursing (BSN) is a professional nursing program that develops an individual’s nursing career on the foundation of knowledge in humanities, science, and other associated professional disciplines. BSN graduates are molded to become general clinical practitioners. The BSN coursework give particular focus to critical thinking, health and human functioning, care and therapeutics, person/environment fit, health care resources, role development, decision making, and health status evaluation (School of Nursing). Undoubtedly, greater knowledge in various areas of science is particularly important to meet the goals of the BSN coursework comprehensively. The Western Governors University gives a detailed description regarding the humanities and science pre-requisites for a BSN nursing program.