Contact Us
Sign In / Sign Up for FREE
Go to advanced search...

Topics in Clinical Biochemistry and Haematology (Haematology) - Essay Example

Comments (0) Cite this document
Based on John’s clinical history and the presented signs and symptoms, the underlying pathology of his condition is most likely to be caused by autoimmune haemolytic anaemia. There is however a number of other likely diagnoses that should be taken into consideration before an…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER98.9% of users find it useful
Topics in Clinical Biochemistry and Haematology (Haematology)
Read TextPreview

Extract of sample "Topics in Clinical Biochemistry and Haematology (Haematology)"

Download file to see previous pages Sideroblstic anaemia can either ne inherited or acquired but in Johns case, an inherited disease is ruled out because he is already 64 years old and has never experienced any related disorder. Vitamin B6 and copper deficiencies are some of the likely precipitants of sideroblastic anaemia. Another probable diagnosis for John’s condition is Zieves syndrome but the condition can also be ruled out in John’s case because he has no history of prolonged alcohol abuse. John’s condition can therefore be diagnosed as autoimmune haemolytic anaemia. The diagnosis of John’s case was confirmed by the results of the Comb’s test which was carried out. For example, the test revealed some aggregation in the red blood cells and is likely to have been caused by action of antibodies against the red blood cells.
The results of full blood count (FBC) are significantly important in the determination of an individual’s health status, assessment of drug treatment and dietary deficiencies as well as during the diagnosis of a number of hematologic conditions. On the other hand, blood biochemistry tests such as Comb’s test can effectively be used to check for a number of abnormalities in the body chemistry (Blann, 2007, p.56). In most haematology laboratories, full blood count and biochemistry tests are some of the widely used wide screening methods that are often applied to check for the presence of disorders such as anaemia(decreased haemoglobin or red blood cells), infections as well as a number of other common diseases that can be manifested in different parts of the blood.
FBC may also be requested or performed in a number of other more specific situations such as to determine the severity of blood loss in an individual, help diagnose diseases such as anaemia and leukaemia, monitor the response to some types of drug treatment as well as to investigate the history of abnormal clotting or bleeding. Healthy individuals are generally ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Topics in Clinical Biochemistry and Haematology (Haematology) Essay”, n.d.)
Topics in Clinical Biochemistry and Haematology (Haematology) Essay. Retrieved from
(Topics in Clinical Biochemistry and Haematology (Haematology) Essay)
Topics in Clinical Biochemistry and Haematology (Haematology) Essay.
“Topics in Clinical Biochemistry and Haematology (Haematology) Essay”, n.d.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF Topics in Clinical Biochemistry and Haematology (Haematology)

Haematology Exam Questions

...Haematology Exam Questions Describe briefly how Full Blood Count analyser enumerates the following: i. Total white cell count The normal count of the total white cell count in adults is 4.0-10.0×109/L. A low count on the white cell may indicate that a patient is suffering from a spleen or liver disorder and presence of toxic substance whereas a high total white cell count may indicate tissue damage, inflammatory diseases or an infection. ii. Differential white cell count The ranges of the normal differential white cell count in adults in the different types of white cells are: 0.02-0.5×109/L in eosinophils, 1.0-3.0×109/L in lymphocytes, 0.05-0.1×109/L in basophils, 2.0-7.0×109/L in neutrophils and 0.2-1.0×109/L in...
18 Pages(4500 words)Coursework


...? Haematology - Haemostasis Vascular injury initiates various multistep processes to ensure that a clot is formed at the site of injury to prevent any loss of blood. Two important steps involved in the prevention of blood loss and repair include platelet plug and fibrin clot formation. Initial damage to the endothelial wall promotes the expression of von Willebrand factor (vWF) on the damaged cells at the site of injury. These factors acts like a glue to adhere the fast moving platelets with the strength sufficient enough to withstand the streamline force of the blood. There are certain glycoproteins present on the platelet surface that takes part in platelet adhesion and aggregation. Also the collagen receptors present...
14 Pages(3500 words)Essay


...? Clinical Cases; Questions and Answer Part Case Study Glycaemic status Question Blood glucose monitoring has been an important tool in the effective management of out-patients with diabetes. This tool which entails self monitoring of blood glucose level in a specified period has been designed to help in glycaemic control and lowered the risk associated with high blood sugar level. Considering the result of the biochemical analysis done for the patient, it can be concluded that the patient has not been monitoring his blood sugar effectively. Each of those outlined results point towards different analysis and help in the assessment of a poorly controlled blood sugar. Fasting blood glucose clearly shows a higher value that...
6 Pages(1500 words)Case Study

Haematology (case study assignment)

...?Haematology Case Study Assignment Haematology Case Study Assignment Disease and its Many people often suffer from different malignant bone tumors. The malignant bone tumors usually form a group of lesions that differ in their behavior and tissue makeups. Moreover, they range from locally aggressive tumors that never metabolize to high grade sarcomas that often demonstrate poor prognosis. Malignant bone tumors usually affect all ages and barely all bone sites. Moreover, there are numerous malignant bone tumors with each having specific diagnosis and critical method of treatments (Anderson and Ghobrial, 2008; p. 12). Therefore, it is vital that each malignant growth is given an accurate diagnostic test...
6 Pages(1500 words)Essay

Haematology and immunology

.../2008_booklet_understanding_MPD.pdf MUGHAL, T. I., & GOLDMAN, J. M. (2008). Chronic myeloproliferative disorders. London, Informa Healthcare. MURUGESAN G, ABOUDOLA S, SZPURKA H, VERBIC MA, MACIEJEWSKI JP, TUBBS RR, & HSI ED. (2006). Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis. American Journal of Clinical Pathology. 125, 625-33. SILVER, R. T., & TEFFERI, A. (2008). Myeloproliferative disorders: biology and management. New York, N.Y., Informa Healthcare....
6 Pages(1500 words)Essay


.... Treatment with bisphosphonates is always started for individuals who have experienced osteolytic lesions, osteoporosis and or osteopenia. Better treatment should however be commenced when the myeloma disease has progressed to symptomatic myeloma level. However, regular participation in clinical trials is also encouraged. Clinical trials are sets of tests in medical research and drug development that are used to assess the impact of certain drugs that are used for treatment specifically for health interventions. This prevents an individual from getting adversely affected by the drugs from treatment since they are able to offer personal information on their feelings as they use the drugs. These...
4 Pages(1000 words)Essay


...anaemia. Folate deficiency also occurs because of the increased requirements of folate when red blood cell production increases. Haemolysis can be congenital or acquired. Clinical conditions of this type of anaemia are pallor, jaundice, and variably splenomegaly. Those chronically hyperbilirubinaemic are vulnerable to develop pigment gallstones and this can lead to obstructive jaundice (Davey, 2012, p. 340). Common causes of haemolytic anaemia are of two types. In congenital/hereditary type, the causes are “Hereditary spherocytosis, Glucose -6-phosphate dehydrogenase (G6PD) deficiency, Pyruvate kinase deficiency, Sickle cell anaemia and Thalassaemia” (Davey, 2012, p. 341). Due to a hereditary biochemical lesion in...
3 Pages(750 words)Essay

Clinical biochemistry

...? Clinical Biochemistry Assignment Other (s) Clinical Biochemistry Assignment Enzymes COMT (Catechol-O-methyltransferase) COMT (Catechol-O-methyltransferase) is an important enzyme that acts as a catalyst in the transfer of methyl group from S-adenosylmethione to catecholamines including epineprhrine, neurotrsnmitters, dopamine and nonepineprhrine (BRENDA 2). The process of O-methylation normally occurs in one of the degenerative pathways of catecholamine transmitters. In this regard, the pathways include dopamine degradation and betaxanthin biosynthesis. Encoded by COMT gene, Catechol-O-methyltransferase also plays a critical role in the metabolism of many catechol drugs used in the treatment of hypertension, Parkinson’s disease... Clinical...
3 Pages(750 words)Assignment


..._____________ ID: _________ ID: __________ Haematology Cell haematology has adopted the language of 'proliferation' to refer to those possible ways, that suggest cells multiplication in organisms, and that in a rapid manner. In particular, the language of proliferation is central to the study of leukaemia or cancers. The connection between cell proliferation and cancer is a harmless, natural process and it is essential to life. Mutimer (2000) states that proliferation is managed by a series of biological control mechanisms that regulate the growth of cells in such a manner that they reproduce what is coded into their genetic material. Once these mechanisms fail and the cells reproduce without control,...
2 Pages(500 words)Essay

Clinical Biochemistry and Haematology

...Clinical Biochemistry and Haematology What is the differential diagnosis? Differential diagnosis is methodical diagnostic systems that is used to spot the existence of an entity in cases where there are various alternatives are possible. Becker et al (2005) explain that it is the process is sometimes referred to as differential diagnostic procedure. The term may also be used in reference to any of the incorporated candidate alternatives; referred to as the candidate condition. One of the most important aspects of the differential diagnosis is that it is an essential process of elimination or at least of getting relevant information and details that reduces the “possibilities” of...
10 Pages(2500 words)Book Report/Review
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Essay on topic Topics in Clinical Biochemistry and Haematology (Haematology) for FREE!

Contact Us