EPIDEMIOLOGY OF HEPATITIS B VIRUS - Term Paper Example

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Hepatitis B virus (HBV) is a DNA (double stranded) virus belonging to Hepadnaviridae family that targets the liver to cause a chronic or an acute potentially life-threatening disease. Hepatitis due to HBV infection has become a global challenge because as per the World Health…

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Subject: Miscellaneous
Type: Term Paper
Level: Ph.D.
Pages: 7 (1750 words)
Downloads: 2
Author: jakaylaschaefer

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Annual worldwide mortality due to hepatitis viral diseases is estimated to be between 500,000 to 700,000 (WHO, 2010), HCC being the 5th highest killer cancer in the world (Parkin, 2001). The hepatitis B virus is 50 to 100 times more infectious than human immunodeficiency virus (HIV) and about 25% of the infected children would carry a chronic disease into adulthood and would die from hepatic cirrhosis or hepatocellular carcinoma (Seeger and Mason, 2000). Figure 1 shows the geographical distribution of the HBV prevalence.

The worldwide prevalence of HBV infection can be broadly divided into three kinds of regions a) Highly endemic areas where the prevalence rates are very high i.e. more than 8%; b) Intermediate prevalence (2 – 7 %); and c) Low prevalence areas (

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