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Biochip microfludic vortex chamber - Essay Example

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To perform the tasks, COMSOL Multiphysics simulation environment is used. The properties investigated are fluid flow, diffusion and convective, and electric…
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Biochip microfludic vortex chamber
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Biochip microfludic vortex chamber

Download file to see previous pages... These modules deal with movement of fluid in biochip microfluidic vortex chamber, the diffusion and concentration with time of fluid also the electric conductivity between electrodes in chamber. We also illustrate fluid flow in the media channel and the vortex.
Biotechnology has emerged as a new technology which can assist in production or modification of molecules and cells, and development of new and useful products, processes, or services. During the process, it is important to study the reactions that occur in the cells leading to desired changes. These reactions or properties can be studied by changing the physical and chemical environment using biochip microfluidic.
Microfluidic biochips have revolutionised the clinical diagnosis, DNA Sequence, and other procedures involving molecular biology. Development in this technology has opened further avenues for enzymatic and DNA analysis, including the analysis of proteins and protein peptides, immune, drug delivery implant devices, and environmental monitoring and toxicity assessment (Chakrabarty & Zeng, 2005). With further experimentation and usage of biochips, integration and complexity of design systems is expected to rise dramatically.
For the purpose of this paper, a circular vortex chamber is used which opens into an outlet into a media channel. Opposite to the outlet channel, there is an opening for a control inlet. Cells are pushed into the vortex chamber through the control inlet while keeping the outlet closed. Once the cells are in the chamber, the inlet can be closed, the outlet opened and fluid can be passed through the media channel. As the fluid is passing, the cells in the chamber start to circulate. Two-way diffusion takes place between the chemical species in the circulating fluid inside the vortex and the fluid in the media channel. However, owing to negligible diffusion rates, very little movement takes place from the ...Download file to see next pagesRead More
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