Haematology as a Branch of Medicine - Essay Example

The type of a cell to become is determined by pluripotent cells that differentiate it wisely. 1Proliferation is the multiplication of blood cells in a human being. When an embryo is being developed, the formation of blood takes place in the yolk sac in an aggregate of blood cells. Blood formation takes place in the liver, spleen, and lymph nodes and development goes to advanced stages.

Eventually, the task of blood formation is taken by the bone marrow in the entire body system when they develop. However, the proliferation of lymphoid cells usually occurs in the secondary lymphoid organs such as lymph nodes, spleen, and thymus. In adults, hematopoiesis usually takes place in marrows of long bones like femurs and also in ribs and sternum where we have spongy bones. At times, the spleen, liver, and thymus recommence their hematopoietic function commonly known as extramedullary hematopoiesis.

2Haematopoiesis does occur in ovaries, kidneys, gut, and spleen where there is a loose stroma of connective tissues in some vertebrates. Differentiation is a process whereby cells acquire a type regarding hemopoiesis. During differentiation, cell morphology changes drastically although generic material remains the same with a few exceptions. In many aspects of cell physiology, differentiation involves changes regarding shape, metabolic activities, polarity, size, and responsiveness to signals whereas gene expression profiles changes during differentiation.

Blood cells are usually divided into three lineages namely: erythroid cells, lymphoid cells, and myeloid lineage. The division of blood cells responsible for carrying oxygen is the erythroid cells while on the other hand, those responsible for the immune system are the lymphoid cells. Myeloid cells are responsible for roles such as adaptive immunity, innate immunity, and blood clotting. Self-renewal as far as hemopoiesis is the ability of the cells of the cell to multiply and increase in number thereby replacing the worn out and old ones. The control factor that influences the process of blood formation is the ability of the cells to form and become many different types a process known as pluripotent.