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Medical Physiology - Case Study Example

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In the paper “Medical Physiology” the author discusses the case of a 28-year-old woman who cuts her hand while dicing vegetables in the kitchen. The wound is cleaned and sutured. Five days later, the site of injury contains an abundance of chronic inflammatory cells…
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Medical Physiology
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Download file to see previous pages D. Smooth muscle cells: Though smooth muscle cells are recruited by day 3 or 4 of the wound along with fibroblasts, myofibroblasts, pericytes, and smooth muscle cells, their main role is fibroplasia, synthesis of connective tissue matrix, tissue remodeling, wound contraction, and wound strength. They do not produce cytokines and chemoattractants (Sephel, 72). Hence this is not the correct answer.
A 68-year-old man with prostate cancer and bone metastases presents with shaking chills and fever. The peripheral WBC count is 1,000/uL (normal = 4,000-11,000/uL). Which of the following terms best describes this hematologic finding?
A. Leukocytosis: This is not the correct answer because leukocytosis means an increase in WBC count in the peripheral blood beyond 11000/uL. It is most commonly associated with bacterial infections and tissue injury (Ganong, 518-520). The contribution to leukocytosis can be from neutrophils, eosinophils, basophils, monocytes, lymphocytes or all.
B. Leukopenia: This is the correct answer because WBC count less than 4000/uL is known as leukopenia. It occurs in chronic inflammation, typhoid, certain viral infections, rickettsial infections and chronic debilitating disease such as disseminated cancer (Ganong, 518-520).
C. Neutrophilia: This is not the correct answer because neutrophilia means an absolute increase in neutrophils. Neutrophilia actually causes leukocytosis. It occurs in acute bacterial infections (Aster, 664)
D. Pancytopenia: This is not the correct answer because pancytopenia means a decrease in all types of blood cells- WBC, RBC, and platelets. Pancytopenia is generally due to diseases affecting the bone marrow like myelofibrosis, leukemia, aplastic anemia, and the malignant form of osteoporosis. ...Download file to see next pagesRead More
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