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The Stem Cell Technique in Treatment of Alzheimer's and Parkinson's Diseases - Essay Example

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This research paper examines the stem cell therapy as the best future treatment approach for Alzheimer’s and Parkinson’s disease, as compared to other options such as cell therapy and deep brain stimulation. Stem cell therapies consist of treatment measures related to regenerative medicine…
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The Stem Cell Technique in Treatment of Alzheimers and Parkinsons Diseases
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"The Stem Cell Technique in Treatment of Alzheimer's and Parkinson's Diseases"

Download file to see previous pages This essay The Stem Cell Technique in Treatment of Alzheimer's and Parkinson's Diseases explores treatment options for Alzheimer’s and Parkinson’s disease. Currently available pharmacological therapies for Parkinson’s disease such as Levodopa, Selegiline, Amantidine, Anticholinergics, Dopamine receptor agonists, and Catechyl-O-methyl transferase (COMT) inhibitors can neither arrest nor reverse the progression of the disease; hence no cure has been found for PD so far. Ablative surgery for patients with Parkinson’s and other movement disorders, creates a permanent lesioning of tissue to ostensibly inhibit overactive neuronal activity. Deep Brain Stimulation (DBS) has replaced ablation of tissue in the basal ganglia and the thalamus. DBS mimicks ablation, without causing permanent damage (Benabid, 2003). Hardesty and Sackeim (2006) believe that the therapeutic properties of high frequency DBS on both white and grey matter targets are due to an excitatory axonal response. The mechanism of DBS is based on a combination of inhibition and excitation, resulting in neuronal jamming and silencing, as well as axon stimulation. By switching off the disrupting activity causing the movement disorder, the application of a new type of frequency that has beneficial effect, is possible. New research has introduced neurosurgical approaches based on ready to use and commercially available equipment for deep brain stimulation of the subthalamic nucleus, and also lesion or stimulation of the globus pallidus to a lesser extent. ...Download file to see next pagesRead More
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