CHECK THESE SAMPLES OF Pharmacology: the Bioavailability of Lignocaine
The paper "Chemical Structure of lignocaine" states that Lignocaine reversibly inhibits the conduction of action potentials in nerves and other excitable membranes.... In phase O of the cardiac potential, the antiarrhythmic effects of lignocaine occur, resulting in the blockage of the Na+ channels and leading to the reduced influx of the Sodium ions into the myocardial cell.... lignocaine blocks the Voltage-gated Na + channels present in the neuronal membrane by acting as a local anaesthetic....
9 Pages
(2250 words)
Essay
pharmacology Name: Instructor: University: Course: Date: Administration of medication in hospitals requires a lot more than giving patients their medication.... According to the AFH rules, caregivers must always be aware of every patient's medication administration schedule, why the patient is being given the medication, its effects and any side effects that could arise....
4 Pages
(1000 words)
Assignment
This feature of pro-drugs is employed to enhance the bioavailability and pharmacokinetic properties of pharmacologically potent compounds.... It is against this background that pro-drugs and their utility in overcoming the limitations of bioavailability and pharmacokinetics profiles has become a significant subject of study in pharmacology (Shek, 1994).... his understanding of the possibility of enzymatic action to create active therapeutic agents has now become the basis of overcoming the problems of potential drug candidates demonstrating poor therapeutic effects, because of poor bioavailability and pharmacokinetic profiles....
12 Pages
(3000 words)
Essay
Its impact in terms of reducing brain oedema has made it a favourable option for neurosurgeons.... However, in recent years it has fallen out of favour in its use.... ... ... Mannitol is considered an osmotic diuretic agent and also a renal vasodilator.... It is applied clinically for osmotherapy in order to decrease intracranial pressure until other treatment options can be applied (Battison, Andrews, Graham, and Perry, 2005)....
34 Pages
(8500 words)
Essay
Particularly, the study shall delve on the form of medication that the patient (known as Sally Smith) has been taking, her historical health background and the best treatment.... ... ... Subsequently, the case study shall determine the pharmacokinetics of each medication that she has been using, the probable adverse effects of the drugs and a discussion on the considerations for the appropriate diagnostic tests that could be applied towards the assessment of her condition and thus; provide her with appropriate education on how to handle her condition (Rice, 2010)....
4 Pages
(1000 words)
Essay
Along with cytochrome P450, CD243 limits the bioavailability of drugs by reducing their cellular.... For example, it inhibits the bioavailability of orally administered drugs by transporting them back into the intestinal lumen (Finch & Pillans, 2014).... ifferent studies have been conducted in which various inhibitors of P-gp (MDR1) have been used to evaluate the bioavailability of drugs following the inhibition of MDR1.... A study conducted to determine the bioavailability of digoxin following the administration of rifampin revealed that the plasma concentration of digoxin dropped significantly....
6 Pages
(1500 words)
Assignment
This is possible because of the fact that pregabalin has a bioavailability of 90%, which gives it a better pharmacokinetic profile.... The researcher of the following paper states that the definition of neuropathic pain according to the International Association for the Study of Pain (IASP) is 'all pains initiated or caused by a primary lesion or dysfunction of the nervous system' (Bouhassira, 2001)....
10 Pages
(2500 words)
Case Study
The paper "Important Preparations in Pharmacology" describes that the physicochemical properties of any drug include lipophilicity, solubility, Ionization constants, meting point, and bioavailability, the volume of distribution, and half-life of the drug.... ... ... ... The half-life of the Sotalol in dogs was 4....
5 Pages
(1250 words)
Lab Report