Epidemiology and Biostatistics - Assignment Example

The treatment of all intervention groups is done identically apart from the experimental treatment (Jadad, 2007). Nevertheless, we find that the analysis of patients is usually done within the group that they belong, regardless of whether they were affected or even experienced the intervention that was intended; that is intention to analysis treatment. The focus of the analysis is on the approximation of the size of disparities in the predefined results between the intervention groups. In order to be in a position of having a good understanding of what randomized control studies are, we are going to look at a well-controlled study that shows that some children a well-controlled research study showing that some children who have autism can possible gain or benefit from a diet that is free of gluten and a casein.

It has been suggested by several scientists that the children who have autism might show some kind of behaviors that appears not to be usual due to the fact that they do not digest dairy products or grains in a proper manner, or as they should. As a result, we find that their intestines may perhaps leak the by-products of proteins into their systems, and the by-products might consequently turn out to be a drug in the young brains. Of the children concerned. This study is purposely carried out to try and establish whether it is possible that an elimination diet can assist in the improvement of the behavior of the children who have autism with the by-products of proteins that are not usual, in their urine.

Nonetheless, the focus of the research was on twenty children who have autism; that is one that have their ages ranging between five and eleven years, with protein by-products in their urine that are not usual or normal. In the experiment, ten of the children will be put on a diet that is strictly free of casein and gluten for a period of twelve months, and those who are remaining will be given a control diet. This control diet will be inclusive of both the products of milk and grain. Then, those individuals who will act as observers will not be aware or have any idea of the diets of each and every child during the process of rating the behavior of each one of them.

After the experiment was carried out and observations made, it was found that considerable improvements from prior or before to after the entire period of twelve months were evident in the control group. What was seen in the improvements included substantial fall in the attention matters, rise in the cognitive ability, together with improvements in the psychological, social as well as communication skills. Although these kinds of studies are important tools, practical and ethical concerns limit their application.

Patients being exposed or subjected to an intervention that is thought to be inferior to the present treatment is normally regarded to be unethical. For instance, a non-random trial or research established that the supplementation of multivitamin in times of pregnancy could lead to the prevention of defects in the neural tube in children. However, even though the research had serious errors, committees on ethics were not ready to deny patients this possibly important treatment, which made it very hard to conduct the experiment which later came to indicate that the most effective part or section of the multivitamin cocktail was folic acid (Matthews, 2006).

On the other hand, we find that