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The role of cellular pathology in investigation of lymphoma - Essay Example

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The Role of Cellular Pathology in Investigation of Lymphoma Student ID Number & Code Date Total Number of Words: 2,996 Introduction Lymphoma is actually a type of blood cancer cell that develops as part of the immune system…
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The role of cellular pathology in investigation of lymphoma

Download file to see previous pages... 414). The presence of extranodal lymphoma is a serious health condition because it can adversely affect other organs like the brain, bones, and the skin. Similar to lyphoid leukemia, lymphomas can originate in lymphocytes which involves the blood circulation and bone marrow. According to Parham (2005, p. 414), lymphomas that originates in lymphocytes will not trigger the development of static tumors. The main function of lymphocytes is to detect not only the presence of infectious organisms or pathogens like virus and bacteria which may invade the human body or the presence of any forms of abnormal cells such as cells that are infected by virus or bacteria and the presence of cancer cells (Martini et al., 2007, p. 578). When this happen, the lymphocytes work to destroy either the infectious organism or response to the presence of abnormal cells. Specfically the B lymphocytes function by producing protein antibodies that will circulate around the lymph and blood to carry out invasive pathogens and abnormal cells in the body. On the other hand, the T lymphocytes is responsible in killing the pathogens that are transported by the B lymphocytes from the affected area (Bender et al., 1997, p. 164). Lymphoma happens when the B or T cells uncontrollably grow and multiply to form a cancerous mass or tumors (Bertrand et al., 2010; Connors, 2009). Even though lymphoma is a type of cancer that is cureable, between 40% to 70% of the affected person may not survive (Lymphoma Research Foundation, 2012). To improve the treatment given to patients with lymphoma, it is necessary on the part of the healthcare professionals such as the cytopathologists or cytotechnologists to closely examine and have a better understanding with regards to the role of cellular pathology in investigating incidence of lymphoma. As part of going through the main discussion, it is necessary to identify and discuss the types, subtypes and classification of lymphoma. Eventually, the importance of cellular pathology with regards to investigating lymphoma will be tackled in details followed by discussing the common laboratory tests used in investigating cases of lymphoma. Types, Subtypes, and Classification of Lymphoma Classified under hematological neoplasm, lymphomas may develop under different classification, form, and type. In 1832, the first study on lymphoma was published by Thomas Hodgkin. For this reason, the first type of lymphoma is known as the Hodgkin’s lymphoma (Hellman and Mauch, 1999, p. 5; Kuppers and Rajewsky, 1998). The other type of lymphoma is known as the non-Hodgkin’s lymphoma (Kramer et al., 2012; Bertrand et al., 2010; Swerdlow et al., 2008). The Hodgkin’s and non-Hodgkin’s lymphoma develop in almost the same way except for the fact that the tissue cells that is affected by the Hodgkin’s lymphoma is composed of a single type of cell known as the Reed Sternberg cell (Kuppers and Rajewsky, 1998). In most cases, the Hodgkin’s lymphoma can be found not only in the lymph nodes but also in other organs like the bone, bone marrow, liver, lungs, and spleen (Connors, 2009). Examples of Hodgkin lymphoma includes: nodular lymphocyte predominant Hodgkin lymphoma, and the four (4) subtypes of classic Hodgkin lymphoma (CHL) which includes the mixed cellularity CHL, the nodular sclerosis CHL, lymphocyte-rich CHL, and the lymphocyte-depleted CHL (Pileri et al., 2002). Unlike the Hodgkin’s lymphoma, a wide-range of cancer cells fall under the type of non-Hodgkin’ ...Download file to see next pagesRead More
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