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Should Women Be Given HRT - Research Proposal Example

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In the paper “Should Women Be Given HRT?” the author discusses the period when a woman enters menopause. Both the ovaries begin to shrink and levels of estrogen and progesterone fluctuate as the ovaries strive to maintain the hormone production…
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Should Women Be Given HRT
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Download file to see previous pages Heart and Estrogen-Progestin Replacement Study (HERS) and Women’s Estrogen for Stroke Trial (WEST) exhibited that cHRT and unopposed estrogen replacement therapy were ineffective for secondary prevention of cerebrospinal events in postmenopausal women (Hulley, 1998; Viscoli, 2001). These studies have modified our perception towards HRT. The data appears intimidating and has added a lot of mystification to it. Such intriguing results have provoked several questions regarding its use, benefits, and risks. The medical fraternity is desperately seeking the answer to whether HRT is a boon or a bane? What is the ratio of benefit versus risk? Do the risks really prevail over benefits? HRT is reported to increase bone mineral density (BMD) and trim down the risks of fracture but, aggravates the risk of stroke. Is it good news or bad? Which is a more important fracture or a stroke? We do not know how reliable is the data? For instance, the WHI report affirms that ‘estrogen therapy caused fewer cases of breast cancer but the data was not statistically significant’? How can that be possible? How do we interpret such deceptive data? There are several such important findings in the WHI trial which are insignificant, meaning that either they are probably true – or probably not. Such incomprehensible findings need further confirmation. So should we believe that HRT has serious safety concerns or simply ignore them and relax? There is so much of controversy surrounding this topic. Therefore, the objective of this manuscript was is to present each side of the issue by analyzing various relevant research articles. ...Download file to see next pagesRead More
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