We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Nobody downloaded yet

The relationship between SC35 and E2F1 in the apoptotic response of head and neck cancer cells following cisplatin treatment - Research Paper Example

Comments (0)
Summary
The relationship between SC35 and E2F1 in the apoptotic response of head and neck cancer cells following cisplatin treatment Literature Background: Head and neck cancers are the sixth most common amongst all cancers globally and each year almost 100,800 new cases are diagnosed in Europe alone (Leemans, Braakhuis, & Brakenhoff, 2011)…
Download full paper
GRAB THE BEST PAPER
The relationship between SC35 and E2F1 in the apoptotic response of head and neck cancer cells following cisplatin treatment
Read TextPreview

Extract of sample
The relationship between SC35 and E2F1 in the apoptotic response of head and neck cancer cells following cisplatin treatment

Download file to see previous pages... The impact of head and neck cancers on the health care system can be gauged by the fact that each year almost 500,000 new cases of head and neck cancers occur globally, with almost two thirds of the cases occurring in developing nations (Marur & Forastiere, 2008; Lung, Tascau, Almasan, & Muresan, 2007). There are several risk factors for the development of head and neck cancer but amongst those, the most important are tobacco use and alcohol consumption (Forastiere, Koch, Trotti, & Sidransky, 2001). Studies have revealed that the consumption of tobacco and alcohol has the strongest association with these cancers and these factors have a synergistic effect in the causation of head and neck cancers (Leemans, Braakhuis, & Brakenhoff, 2011). It has been found that tobacco usage increases the risk of developing head and neck cancer from five to up to twenty five-fold (Marur & Forastiere, 2008). Moreover, the use of both tobacco and alcohol leads to a forty times greater risk for these cancers (Marur & Forastiere, 2008). ...
Over the last few years, there has been an increase in the incidence of cancers occurring at the base of the tongue and the tonsils. This changing trend has been attributed to the increase in the occurrence of HPV-associated squamous cell carcinoma (discussed above) which occurs due to HPV infection following oral sex, which has become an increasingly popular practice amongst the younger generation (Marur & Forastiere, 2008). More recently, it has become common practice to classify head and neck tumors into two main subcategories based in the underlying aetiologies and risk factors, viz. HPV-positive and HPV-negative head and neck tumors. Studies have revealed that these tumors belonging to these two categories differ in not only the aetiology and causative factors but also have different underlying molecular mechanisms, which cause them to have different levels of tumor severity and prognosis (Leemans, Braakhuis, & Brakenhoff, 2011). Head and neck cancer is a heterogeneous disease, which can arise due to several different molecular mechanisms, each of which have different implications for the cancer invasiveness, severity, response to treatment, prognosis and patient survival rates (Leemans, Braakhuis, & Brakenhoff, 2011). Cancers are shown to be clonal replications of cells that have acquired certain genetic alterations which cause them to undergo unchecked cellular proliferation. These genetic alterations can occur in two main classes of genes which are important in the cell cycle, viz. proto-oncogenes and tumor suppressor genes (Forastiere, Koch, Trotti, & Sidransky, 2001) In the case of tumors of the head and neck, studies have revealed that the most commonly implicated genetic change in tumors of this region is the loss of region 9p21 ...Download file to see next pagesRead More
Comments (0)
Click to create a comment
CHECK THESE SAMPLES - THEY ALSO FIT YOUR TOPIC
The relationship between SC35 and E2F1 in the apoptotic response of head and neck cancer
Head and neck cancer often occurs in individuals older than 45 years. There is also an association of papilloma virus and development of cancer of the head and neck. Cancer often results from exposure to the virus as a consequence of oral-vaginal or oral-anal sex.
21 Pages(5250 words)Essay
The communicative relationship between the doctor and patient in the treatment of acupuncture
Procedure of Acupuncture The treatment of acupuncture has its origin in China and this procedure is also common in various other East Asian countries and was very commonly practiced approximately 2,000 years ago while some theories also provide evidences of its use around 5,000 years ago.
2 Pages(500 words)Research Paper
Cancer
Another way that healthy cells differ from cancer cells is that healthy white blood cells can detect damaged cells, such as viruses, and attack them, stopping them before they spread the virus to the rest of the body. Cancer cells, however, can pass through this system without being detected, which means that the immune system is not notified to their presence (Skehan 15).
2 Pages(500 words)Research Paper
The arterial and venous blood supply of head, neck and upper limbs
Mentioning the curving aortic arch here would be a worthwhile effort as it is the aortic arch basically which connects the ascending aorta with the descending aorta and through which three major elastic arteries come off namely brachiocephalic trunk which further divides into the right common carotid and right subclavian arteries, left common carotid artery, and left subclavian artery.
6 Pages(1500 words)Research Paper
Henrietta Lacks (HeLa) and her cancer cells and research
http://www.guardian.co.uk/world/2010/apr/04/henrietta-lacks-cancer-cells 4. http://article.wn.com/view/2010/04/04/Henrietta_Lackss_cells_were_priceless_but_her_family_cant_af_v 5. http://mrwhatis.com/johns-hopkins-hospital-henrietta-lack.html 6. http://esciencenews.com/dictionary/Henrietta.Lacks 7.
8 Pages(2000 words)Research Paper
Evidence-Based Practice Implementation in the Treatment of Breast Cancer
This paper contains a summary of an implementation of an EBP guideline for breast cancer patient care and the subsequent evaluation of the effect of its implementation. Various barriers to the complete adaptation of EBP are also examined and some solutions were presented. EBP application towards renal failure was also explored.
5 Pages(1250 words)Research Paper
Cancer Treatment Research Paper
It is also found throughout the world and manifests itself even in other animals and plants. There are a variety of methods of treatment which includes surgery, chemotherapy, radiotherapy, monoclonal antibody treatment, immunotherapy and alternative treatment.
4 Pages(1000 words)Research Paper
Cancer Cells
However, even if an organism has reached its development peak, the dwindling of physiological functions continue, until it reaches the endpoint, senescence. For
10 Pages(2500 words)Research Paper
Snake Venom Protein Paralyzes Cancer Cells
This paper concerns the observing and studying with the revolutionary prospectus in pharmaceutical perspectives, snake venom could pay the way for the fresh age of medicines, as well as the research for treatment of cancer among other illnesses. Snake venoms are often studied by scientists and researchers for its therapeutically/remedial application.
11 Pages(2750 words)Research Paper
The relationship between Henry Miller's novel Tropic of Cancer and Allen Ginsberg's poem Howl
At the beginning of the 20th century global and massive changes in all the spheres of human activities affected literature as well. Writers and other artists began to experiment with the form and content in order to provide something completely new an with its help represent and reflect more clearly so quickly changing world.
8 Pages(2000 words)Research Paper
Let us find you another Research Paper on topic The relationship between SC35 and E2F1 in the apoptotic response of head and neck cancer cells following cisplatin treatment for FREE!
Contact us:
+16312120006
Contact Us Now
FREE Mobile Apps:
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us