Analysis of Genotypic Distributions within Six Population Groups Using Genepop Software - Assignment Example

 Analysis of Genotypic Distributions within Six Population Groups Using Genepop Software Using the Genepop free software; a variety of computer-assisted calculationswere performed upon six distinct population groups, based on numeric values provided at 28 genetic loci. The data points were derived from genotypic profile data based on Polymerase-Chain-Reaction-based loci within the six groups. The specific populations provided are as follows: 1st: African American 2nd: U.S. Caucasian 3rd: Southwestern Hispanic 4th: Bahamian 5th: Jamaican 6th: Trinidadian First, the data was formatted for the Genepop program, involving the removal of alphabetical, and non-numeric items, after which a Hardy-Weinberg probability test was conducted via the computer. The Hardy–Weinberg principle is also known as Hardy-Weinberg equilibrium, HWE, or the Hardy–Weinberg law. Which in essence, states that frequencies of alleles and genotypes remain constant in a population under ideal conditions. A balanced equilibrium should persist throughout the generations barring specific disruption. Disruptions in this equilibrium include non-random mating, selection, mutations, population-bottle-necks or other events that limit population size. Mating overlap between generations, meiotic drive, genetic drift or gene flow. As it is impossible to eliminate all of these conditions at some time from a population, Hardy-Weinberg equilibrium is impossible in nature. But this principle is a useful baseline against which to measure changes that do occur. Static frequencies of alleles throughout a population require a set of theoretical assumptions; deviations in which can give us information about which genes are changing in what way. These assumptions are : Lack of migration or emigration. An infinite population size, completely random mating, and no selective pressures in favor of, or against any genotypes. (Crow, 1999) Violations of the Hardy–Weinberg assumptions trigger deviations from the expectated status quo. The effect depends upon which assumptions are broken. The character of these variations are thought to define the evolution of a species. When a population violates one of the assumptions listed below, the population may continue to exhibit Hardy–Weinberg proportions each generation, but the allele frequencies will be shaped by these deviations. Migration. The way in which two populations are genetically linked. Essentially, allele frequencies blend into homogeneity between the populations. Some models for migration must assume nonrandom mating. Without this randomness, the Hardy–Weinberg assumptions will not be valid. Random mating. The HWP states the population will exhibit a given genotypic frequency following a single generation of random mating within the population. When this assumption is broken, the population will not match Hardy–Weinberg proportions. Three such random-mating violations are as follows: Inbreeding, which raises the likelihood of homozygosity for all genes.Assortative mating, which leads to an increase in homozygosity only for those genes involved in the trait that is assortatively mated, which would also include genes in linkage disequilibrium with them. Small population size, which permits random changes in genotypic frequencies, essentially due to sampling error. Traits which should be rare in a larger population may be disproportionately expressed if a selection event eliminates more common genotypes randomly. The consequences of this effect are called genetic drift. Sampling effects become of vital importance when population sizes are small. Natural Selection causes allele frequencies to shift rapidly. While directional selection eventually winnows out all alleles not specifically favored, there are certain selection methods that can promote equilibrium, such as balancing selection, that preserves specific alleles. The effect of mutations on equilibrium will be subtle in terms of allele frequencies. The change in allele frequencies often parallels the rate of mutation itself within an order of magnitude. While selection may be against a particular mutation, Recurrent mutation will maintain those alleles in the population at a basal level. (Edwards, 1977) It is possible to violate the assumptions of the Hardy–Weinberg principle without the population violating equilibrium. Again, with balancing selection extremes of genotype tend to be selected against in favor of moderation. This can promote an equilibrium with Hardy–Weinberg proportions. This mechanism with selection vs. mutation can be used as the basis for mutation rate calculations. Equilibrium is also aided by sex-linkage; when allele frequencies differ between males and females. Since males must inherit an X chromosome from their mothers (in mammals) Therefore it is easier for male alleles to drift in a pattern that follows females due to maternal inheritance. (Crow, 1999) In terms of testing for deviations from the HWP, Chi-squared tests are generally used, as they are in the case of this study; using the Genepop program. The measured genotype frequencies derived from hard data are compared with the expected genotype frequencies based on Hardy-Weinberg equilibrium. With sufficient population size, the significance of genotype deviations will proceed along an asymototic curve, as is the case in the second, and third Genepop tests. Without a large enough sample, the asymptotic assumption from a Chi-squared test will be invalid. (Crow, 1999) The population sizes of the present Genepop study were sufficient. Upon completion of the first phase of testing, the second option was selected. linkage disambiguation was performed, where each pair of loci in the population was tested. Next, a test was performed for genic differentiation for all pairs of populations. Finally, the results were run in Arlequin format and recorded. The actual raw data and results are included. RESULTS The tests were concerned with the total distribution of particular alleles within the sample populations, which were then extrapolated to yield comparisons of the populations as a whole. The null hypothesis under investigation being: 'alleles are drawn from the same distribution in all populations'. Loci were compared against each other, and populations collectively were paired after the differences were collated. On each locus, an unbiased calculation of the P-value is computed. The test function will be either the probability of the sample – contingent on marginal values, or the G log likelihood ratio. (For the Genic differentiation) Under the first set of conditions, Fisher’s exact probability test is used. (Raymond &Rousset (1995). Genepop's default is now the G test. For the data at hand, after linkage disambiguation and genic differentiation the populations were grouped into pairs. This allowed a determination whether the distribution of alleles is sufficient to reject the Null hypothesis; that the alleles are drawn from the same distributions. Variances were recorded, and the populations were compared. There were five instances where Genepop did not detect highly significant differences: a. African American vs. Bahamian b. African American vs. Jamaican c. Jamaican vs. Bahamian d. African American vs. Trinidadian e. Bahamian vs. Trinidadian In these cases, while differences did exist, they were insufficient to warrant rejection of the Null hypothesis; ergo these populations possess alleles drawn from equivalent distributions. All other pairings between populations resulted in high differences indicating different distribution of alleles. The actual hard data is listed below, converted into a format acceptable by Genepop. -------------------------------------------------------------------------------- Results from GENEPOP -------------------------------------------------------------------------------- Fri Aug 12 09:59:37 WST 2011 Genepop version 4.0.10: Hardy-Weinberg test File: 095937 (African American) Number of populations detected: 6 Number of loci detected: 28 Hardy Weinberg: Probability test ************************ ========================================== Results by locus ========================================== Locus "loc1" not diploid. ----------------------------------------- Locus "loc2" not diploid. ----------------------------------------- Locus "loc3" not diploid. ----------------------------------------- Locus "loc4" not diploid. ----------------------------------------- Locus "loc5" not diploid. ----------------------------------------- Locus "loc6" not diploid. ----------------------------------------- Locus "loc7" not diploid. ----------------------------------------- Locus "loc8" not diploid. ----------------------------------------- Locus "loc9" not diploid. ----------------------------------------- Locus "loc10" not diploid. ----------------------------------------- Locus "loc11" not diploid. ----------------------------------------- Locus "loc12" not diploid. ----------------------------------------- Locus "loc13" not diploid. ----------------------------------------- Locus "loc14" not diploid. ----------------------------------------- Locus "loc15" not diploid. ----------------------------------------- Locus "loc16" not diploid. ----------------------------------------- Locus "loc17" not diploid. ----------------------------------------- Locus "loc18" not diploid. ----------------------------------------- Locus "loc19" not diploid. ----------------------------------------- Locus "loc20" not diploid. ----------------------------------------- Locus "loc21" not diploid. ----------------------------------------- Locus "loc22" not diploid. ----------------------------------------- Locus "loc23" not diploid. ----------------------------------------- Locus "loc24" not diploid. ----------------------------------------- Locus "loc25" not diploid. ----------------------------------------- Locus "loc26" not diploid. ----------------------------------------- Locus "loc27" not diploid. ----------------------------------------- Locus "loc28" not diploid. ----------------------------------------- ========================================== Results by population ========================================== Pop : B0800 ----------------------------------------- Fis estimates --------------- locus P-val S.E. W&C R&H Steps ----------- ------- ------- ------- ------- ------ Pop : C202 ----------------------------------------- Fis estimates --------------- locus P-val S.E. W&C R&H Steps ----------- ------- ------- ------- ------- ------ Pop : H462 ----------------------------------------- Fis estimates --------------- locus P-val S.E. W&C R&H Steps ----------- ------- ------- ------- ------- ------ Pop : 2249 ----------------------------------------- Fis estimates --------------- locus P-val S.E. W&C R&H Steps ----------- ------- ------- ------- ------- ------ Pop : 6567 ----------------------------------------- Fis estimates --------------- locus P-val S.E. W&C R&H Steps ----------- ------- ------- ------- ------- ------ Pop : 3409 ----------------------------------------- Fis estimates --------------- locus P-val S.E. W&C R&H Steps ----------- ------- ------- ------- ------- ------ Normal ending -------------------------------------------------------------------------------- Results from GENEPOP -------------------------------------------------------------------------------- Fri Aug 12 10:31:18 WST 2011 Genepop version 4.0.10, Genotypic linkage disequilibrium File: 103118 (African American) Number of populations detected : 6 Number of loci detected : 28 Markov chain parameters Dememorisation : 1000 Batches : 100 Iterations per batch : 1000 Pop Locus#1 Locus#2 P-Value S.E. Switches ---------- ------- ------- -------- -------- -------- B0800 loc1 loc2 0 0.000000 27821 B0800 loc1 loc3 0.502090 0.017713 22124 B0800 loc2 loc3 0.870030 0.009718 21150 B0800 loc1 loc4 0.300130 0.017159 28632 B0800 loc2 loc4 0.473650 0.016695 27204 B0800 loc3 loc4 0.000000 0.000000 22273 B0800 loc1 loc5 0.726190 0.014660 25227 B0800 loc2 loc5 0.766780 0.014756 24071 B0800 loc3 loc5 0.032960 0.005789 19487 B0800 loc4 loc5 0.378460 0.020220 25390 B0800 loc1 loc6 0.521010 0.023280 18814 B0800 loc2 loc6 0.226840 0.018345 18205 B0800 loc3 loc6 0.737060 0.020314 14316 B0800 loc4 loc6 0.032820 0.007432 19172 B0800 loc5 loc6 0.001100 0.000748 15888 B0800 loc1 loc7 0.473930 0.018423 23300 B0800 loc2 loc7 0.383820 0.020602 22250 B0800 loc3 loc7 0.243050 0.018918 18154 B0800 loc4 loc7 0.954260 0.005557 23683 B0800 loc5 loc7 0.370330 0.023077 20480 B0800 loc6 loc7 0.321520 0.023751 15021 B0800 loc1 loc8 0.127840 0.011119 21985 B0800 loc2 loc8 0.260790 0.015254 21433 B0800 loc3 loc8 0.583060 0.019903 17072 B0800 loc4 loc8 0.786800 0.014245 22503 B0800 loc5 loc8 0.775050 0.015108 19014 B0800 loc6 loc8 0.550210 0.020682 13977 B0800 loc7 loc8 0.000000 0.000000 17840 B0800 loc1 loc9 0.293460 0.019117 16830 B0800 loc2 loc9 0.881480 0.011180 16213 B0800 loc3 loc9 0.195090 0.019731 13287 B0800 loc4 loc9 0.813350 0.014860 16834 B0800 loc5 loc9 0.138050 0.014442 14693 B0800 loc6 loc9 0.031780 0.009175 10709 B0800 loc7 loc9 0.852270 0.015168 13442 B0800 loc8 loc9 0.761290 0.017333 13059 B0800 loc1 loc10 0.759860 0.015354 23072 B0800 loc2 loc10 0.384960 0.020594 22238 B0800 loc3 loc10 0.165570 0.015303 18011 B0800 loc4 loc10 0.278150 0.019811 23697 B0800 loc5 loc10 0.101910 0.011629 20347 B0800 loc6 loc10 0.604690 0.025719 14342 B0800 loc7 loc10 0.984050 0.003907 19120 B0800 loc8 loc10 0.935790 0.007242 17805 B0800 loc9 loc10 0.000000 0.000000 13551 B0800 loc1 loc11 0.808110 0.012962 23396 B0800 loc2 loc11 0.675740 0.016890 22392 B0800 loc3 loc11 0.039610 0.008344 17930 B0800 loc4 loc11 0.724050 0.017603 23462 B0800 loc5 loc11 0.361490 0.021116 20351 B0800 loc6 loc11 0.992500 0.002498 14545 B0800 loc7 loc11 0.661000 0.022591 18740 B0800 loc8 loc11 0.253070 0.018795 17846 B0800 loc9 loc11 0.201640 0.017496 13563 B0800 loc10 loc11 0.813100 0.017737 18610 B0800 loc1 loc12 0.954480 0.006615 18553 B0800 loc2 loc12 0.822600 0.015365 18041 B0800 loc3 loc12 0.218930 0.018270 14461 B0800 loc4 loc12 0.221620 0.019427 18716 B0800 loc5 loc12 0.406840 0.023797 15961 B0800 loc6 loc12 0.986440 0.004453 10964 B0800 loc7 loc12 0.153120 0.019563 14752 B0800 loc8 loc12 0.436170 0.025029 14001 B0800 loc9 loc12 0.732740 0.025584 10619 B0800 loc10 loc12 0.338240 0.025581 14125 B0800 loc11 loc12 0.000000 0.000000 14260 B0800 loc1 loc13 0.754480 0.014148 20573 B0800 loc2 loc13 0.455100 0.018570 20093 B0800 loc3 loc13 0.691620 0.018662 16144 B0800 loc4 loc13 0.697860 0.018357 21123 B0800 loc5 loc13 0.798420 0.016694 18541 B0800 loc6 loc13 0.506940 0.026723 13544 B0800 loc7 loc13 0.931540 0.010001 16726 B0800 loc8 loc13 0.017370 0.003883 16108 B0800 loc9 loc13 0.748580 0.020750 12056 B0800 loc10 loc13 0.448540 0.022038 16658 B0800 loc11 loc13 0.363250 0.023531 16733 B0800 loc12 loc13 0.564870 0.024960 12957 B0800 loc1 loc14 0.815810 0.009517 22127 B0800 loc2 loc14 0.734170 0.013151 20732 B0800 loc3 loc14 0.290250 0.017561 17448 B0800 loc4 loc14 0.369100 0.018411 21837 B0800 loc5 loc14 0.783710 0.013789 19303 B0800 loc6 loc14 0.847710 0.014624 15062 B0800 loc7 loc14 0.062760 0.007737 18241 B0800 loc8 loc14 0.251320 0.014984 17400 B0800 loc9 loc14 0.129280 0.014050 13407 B0800 loc10 loc14 0.336930 0.019539 18228 B0800 loc11 loc14 0.963830 0.004988 17998 B0800 loc12 loc14 0.475030 0.021649 15098 B0800 loc13 loc14 0.000000 0.000000 16412 B0800 loc1 loc15 0.109860 0.009377 30384 B0800 loc2 loc15 0.548480 0.014787 29310 B0800 loc3 loc15 0.092260 0.008264 23841 B0800 loc4 loc15 0.841720 0.011277 30927 B0800 loc5 loc15 0.533830 0.016833 27647 B0800 loc6 loc15 0.364530 0.022371 20175 B0800 loc7 loc15 0.839160 0.010801 25299 B0800 loc8 loc15 0.273900 0.015634 23535 B0800 loc9 loc15 0.862360 0.012239 18080 B0800 loc10 loc15 0.947050 0.007037 24967 B0800 loc11 loc15 0.936510 0.006364 25208 B0800 loc12 loc15 0.539310 0.021354 19674 B0800 loc13 loc15 0.985620 0.002309 22251 B0800 loc14 loc15 0.727870 0.014068 23189 B0800 loc1 loc16 0.083040 0.009621 16259 B0800 loc2 loc16 0.543510 0.017513 15648 B0800 loc3 loc16 0.355540 0.020811 12459 B0800 loc4 loc16 0.216530 0.019642 16027 B0800 loc5 loc16 0.869310 0.012894 14012 B0800 loc6 loc16 0.344810 0.025431 10270 B0800 loc7 loc16 0.596950 0.021222 13187 B0800 loc8 loc16 0.724370 0.019001 12467 B0800 loc9 loc16 0.414530 0.023815 9118 B0800 loc10 loc16 0.270420 0.019279 12969 B0800 loc11 loc16 0.224050 0.021869 12845 B0800 loc12 loc16 0.311540 0.022100 10205 B0800 loc13 loc16 0.313690 0.018976 11535 B0800 loc14 loc16 0.990520 0.001796 12988 B0800 loc15 loc16 0.000000 0.000000 17294 B0800 loc1 loc17 0.783070 0.011863 27749 B0800 loc2 loc17 0.711640 0.014668 26739 B0800 loc3 loc17 0.823830 0.012154 20917 B0800 loc4 loc17 0.127920 0.011197 25972 B0800 loc5 loc17 0.923000 0.008392 23253 B0800 loc6 loc17 0.727090 0.016965 17974 B0800 loc7 loc17 0.211770 0.013528 21648 B0800 loc8 loc17 0.596700 0.018988 20558 B0800 loc9 loc17 0.306660 0.018898 16122 B0800 loc10 loc17 0.455950 0.023051 21760 B0800 loc11 loc17 0.959480 0.006179 21406 B0800 loc12 loc17 0.621170 0.019816 17559 B0800 loc13 loc17 0.871950 0.010897 19417 B0800 loc14 loc17 0.794440 0.011082 20363 B0800 loc15 loc17 0.989150 0.001784 27747 B0800 loc16 loc17 0.140810 0.014589 15429 B0800 loc1 loc18 0.472480 0.016911 27942 B0800 loc2 loc18 0.604240 0.016331 26532 B0800 loc3 loc18 0.736240 0.015726 20359 B0800 loc4 loc18 0.358810 0.016539 26589 B0800 loc5 loc18 0.922920 0.007286 23275 B0800 loc6 loc18 0.890110 0.011514 16821 B0800 loc7 loc18 0.756530 0.014934 21143 B0800 loc8 loc18 0.937230 0.007739 20198 B0800 loc9 loc18 0.696600 0.019793 15421 B0800 loc10 loc18 0.265200 0.017639 21014 B0800 loc11 loc18 0.389820 0.022829 21091 B0800 loc12 loc18 0.098210 0.014964 16472 B0800 loc13 loc18 0.315940 0.017801 19014 B0800 loc14 loc18 0.778330 0.012313 20427 B0800 loc15 loc18 0.296300 0.015313 28057 B0800 loc16 loc18 0.092210 0.009564 14810 B0800 loc17 loc18 0.000000 0.000000 26755 B0800 loc1 loc19 0.156100 0.010900 40769 B0800 loc2 loc19 0.028130 0.005273 38132 B0800 loc3 loc19 0.780420 0.013396 30838 B0800 loc4 loc19 0.552000 0.013722 40209 B0800 loc5 loc19 0.646320 0.017970 35906 B0800 loc6 loc19 0.666150 0.019336 27447 B0800 loc7 loc19 0.070440 0.007123 33374 B0800 loc8 loc19 0.058810 0.007118 31296 B0800 loc9 loc19 0.611640 0.019455 23378 B0800 loc10 loc19 0.363100 0.018072 33560 B0800 loc11 loc19 0.194170 0.014363 33073 B0800 loc12 loc19 0.204570 0.015002 26330 B0800 loc13 loc19 0.830630 0.011165 29541 B0800 loc14 loc19 0.021730 0.004553 29226 B0800 loc15 loc19 0.613620 0.013021 43668 B0800 loc16 loc19 0.906620 0.008023 22234 B0800 loc17 loc19 0.335890 0.014657 37965 B0800 loc18 loc19 0.655930 0.014493 40264 B0800 loc1 loc20 0.969450 0.004121 21057 B0800 loc2 loc20 0.376850 0.017380 19990 B0800 loc3 loc20 0.851100 0.013085 16084 B0800 loc4 loc20 0.045810 0.006855 21324 B0800 loc5 loc20 0.498700 0.020937 18168 B0800 loc6 loc20 0.009070 0.005540 13441 B0800 loc7 loc20 0.160490 0.015480 16791 B0800 loc8 loc20 0.620500 0.019861 16059 B0800 loc9 loc20 0.217830 0.020011 12012 B0800 loc10 loc20 0.664690 0.022243 16692 B0800 loc11 loc20 0.528930 0.023174 16824 B0800 loc12 loc20 0.863590 0.013942 13357 B0800 loc13 loc20 0.698410 0.018195 15312 B0800 loc14 loc20 0.029840 0.005571 16434 B0800 loc15 loc20 0.507230 0.017033 22144 B0800 loc16 loc20 0.054690 0.007964 11514 B0800 loc17 loc20 0.289530 0.019516 20207 B0800 loc18 loc20 0.895550 0.008654 20139 B0800 loc19 loc20 0.000000 0.000000 29327 B0800 loc1 loc21 0.285260 0.015799 32834 B0800 loc2 loc21 0.517530 0.015401 31026 B0800 loc3 loc21 0.304070 0.015593 24580 B0800 loc4 loc21 0.745250 0.011560 32192 B0800 loc5 loc21 0.462790 0.016034 28477 B0800 loc6 loc21 0.421020 0.020084 20771 B0800 loc7 loc21 0.983990 0.002709 25955 B0800 loc8 loc21 0.800990 0.011679 24487 B0800 loc9 loc21 0.838530 0.014749 18608 B0800 loc10 loc21 0.096690 0.012057 25913 B0800 loc11 loc21 0.714700 0.016240 26078 B0800 loc12 loc21 0.557280 0.021170 20289 B0800 loc13 loc21 0.476030 0.018699 23281 B0800 loc14 loc21 0.174950 0.011314 24022 B0800 loc15 loc21 0.127520 0.010236 34658 B0800 loc16 loc21 0.192910 0.014011 17492 B0800 loc17 loc21 0.695710 0.014967 31445 B0800 loc18 loc21 0.002700 0.000763 31856 B0800 loc19 loc21 0.353210 0.013484 47372 B0800 loc20 loc21 0.937200 0.005831 23479 B0800 loc1 loc22 0.161550 0.013207 31302 B0800 loc2 loc22 0.284750 0.015179 29217 B0800 loc3 loc22 0.435840 0.020206 23239 B0800 loc4 loc22 0.831820 0.012461 29552 B0800 loc5 loc22 0.530010 0.017704 26751 B0800 loc6 loc22 0.157050 0.016993 20581 B0800 loc7 loc22 0.075860 0.007812 24941 B0800 loc8 loc22 0.964220 0.004378 23358 B0800 loc9 loc22 0.889580 0.010681 17682 B0800 loc10 loc22 0.797880 0.012991 25412 B0800 loc11 loc22 0.352520 0.018831 24642 B0800 loc12 loc22 0.142260 0.014453 19952 B0800 loc13 loc22 0.955380 0.005999 22225 B0800 loc14 loc22 0.713650 0.014431 22337 B0800 loc15 loc22 0.089030 0.009359 32313 B0800 loc16 loc22 0.238520 0.016743 17018 B0800 loc17 loc22 0.973920 0.003753 29622 B0800 loc18 loc22 0.772990 0.013422 30343 B0800 loc19 loc22 0.465420 0.015642 42276 B0800 loc20 loc22 0.964390 0.004591 22482 B0800 loc21 loc22 0.000000 0.000000 35126 B0800 loc1 loc23 0.274450 0.012130 44401 B0800 loc2 loc23 0.612200 0.013567 40814 B0800 loc3 loc23 0.206980 0.011290 33206 B0800 loc4 loc23 0.100180 0.007309 42565 B0800 loc5 loc23 0.105960 0.007855 38869 B0800 loc6 loc23 0.817440 0.011884 30313 B0800 loc7 loc23 0.858830 0.007827 35847 B0800 loc8 loc23 0.549690 0.013377 33713 B0800 loc9 loc23 0.550110 0.017138 25309 B0800 loc10 loc23 0.280210 0.013035 36692 B0800 loc11 loc23 0.295490 0.013805 35927 B0800 loc12 loc23 0.659060 0.014362 29207 B0800 loc13 loc23 0.570430 0.013331 31554 B0800 loc14 loc23 0.076640 0.006979 30645 B0800 loc15 loc23 0.410570 0.011138 47309 B0800 loc16 loc23 0.705990 0.010893 23961 B0800 loc17 loc23 0.121420 0.007892 41087 B0800 loc18 loc23 0.814760 0.008417 43988 B0800 loc19 loc23 0.294540 0.010396 60419 B0800 loc20 loc23 0.464770 0.015757 31562 B0800 loc21 loc23 0.701060 0.009312 51427 B0800 loc22 loc23 0.660410 0.011385 44989 B0800 loc1 loc24 0.238930 0.011647 30584 B0800 loc2 loc24 0.540790 0.015907 29557 B0800 loc3 loc24 0.101940 0.007814 23947 B0800 loc4 loc24 0.655990 0.014623 29903 B0800 loc5 loc24 0.249230 0.015522 26774 B0800 loc6 loc24 0.172710 0.013898 20590 B0800 loc7 loc24 0.033070 0.005228 24651 B0800 loc8 loc24 0.658100 0.014599 23847 B0800 loc9 loc24 0.074460 0.009835 18313 B0800 loc10 loc24 0.712610 0.015642 25062 B0800 loc11 loc24 0.417300 0.020663 24984 B0800 loc12 loc24 0.956060 0.006048 20442 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0.009384 30508 3409 loc10 loc15 0.527910 0.015904 26807 3409 loc11 loc15 0.407130 0.018163 16419 3409 loc12 loc15 0.098740 0.008947 22195 3409 loc13 loc15 0.152310 0.011305 20754 3409 loc14 loc15 0.198080 0.010507 23337 3409 loc1 loc16 0.543630 0.012555 25155 3409 loc2 loc16 0.648620 0.011189 30706 3409 loc3 loc16 0.298230 0.020252 11198 3409 loc4 loc16 0.766990 0.013815 13731 3409 loc5 loc16 0.815400 0.012114 17131 3409 loc6 loc16 0.490230 0.025147 8087 3409 loc7 loc16 0.613670 0.017720 17344 3409 loc8 loc16 0.705440 0.012274 24143 3409 loc9 loc16 0.738460 0.012630 18985 3409 loc10 loc16 0.954370 0.005838 16849 3409 loc11 loc16 0.436960 0.021565 10759 3409 loc12 loc16 0.414260 0.021362 14540 3409 loc13 loc16 0.286330 0.017978 13397 3409 loc14 loc16 0.295960 0.016039 15075 3409 loc15 loc16 0.000000 0.000000 20240 3409 loc1 loc17 0.069730 0.007017 27324 3409 loc2 loc17 0.351820 0.011629 33204 3409 loc3 loc17 0.633440 0.019247 12413 3409 loc4 loc17 0.066320 0.007877 15151 3409 loc5 loc17 0.078240 0.008893 18785 3409 loc6 loc17 0.949140 0.007359 9452 3409 loc7 loc17 0.636000 0.014456 19405 3409 loc8 loc17 0.663640 0.012095 26462 3409 loc9 loc17 0.501620 0.014193 20891 3409 loc10 loc17 0.518600 0.016448 18882 3409 loc11 loc17 0.338380 0.018928 11912 3409 loc12 loc17 0.336000 0.017138 16174 3409 loc13 loc17 0.811570 0.012242 14508 3409 loc14 loc17 0.829710 0.010771 16296 3409 loc15 loc17 0.003980 0.000904 22182 3409 loc16 loc17 0.073310 0.010068 14048 3409 loc1 loc18 0.304750 0.009143 34513 3409 loc2 loc18 0.912930 0.004547 41941 3409 loc3 loc18 0.793360 0.013320 16281 3409 loc4 loc18 0.728820 0.013654 19739 3409 loc5 loc18 0.000000 0.000000 23265 3409 loc6 loc18 0.080740 0.011232 11278 3409 loc7 loc18 0.477680 0.014916 24247 3409 loc8 loc18 0.879770 0.005652 33410 3409 loc9 loc18 0.415800 0.013857 26173 3409 loc10 loc18 0.224840 0.013977 23283 3409 loc11 loc18 0.536240 0.021577 14656 3409 loc12 loc18 0.558630 0.016665 19869 3409 loc13 loc18 0.380860 0.015757 18895 3409 loc14 loc18 0.765130 0.011200 21425 3409 loc15 loc18 0.060880 0.005409 29903 3409 loc16 loc18 0.441240 0.018274 18674 3409 loc17 loc18 0.001110 0.000615 20435 3409 loc1 loc19 0.253320 0.010169 34322 3409 loc2 loc19 0.047910 0.004136 42712 3409 loc3 loc19 0.624900 0.017302 14723 3409 loc4 loc19 0.181040 0.012098 18118 3409 loc5 loc19 0.431630 0.016649 23032 3409 loc6 loc19 0.654920 0.024060 10614 3409 loc7 loc19 0.322270 0.013837 23868 3409 loc8 loc19 0.868710 0.006420 33353 3409 loc9 loc19 0.448180 0.014168 25597 3409 loc10 loc19 0.526030 0.014990 22967 3409 loc11 loc19 0.853070 0.014082 13338 3409 loc12 loc19 0.361870 0.016941 18201 3409 loc13 loc19 0.892930 0.008863 17646 3409 loc14 loc19 0.818700 0.009863 19850 3409 loc15 loc19 0.489470 0.013204 27412 3409 loc16 loc19 0.796050 0.012286 16973 3409 loc17 loc19 0.460380 0.014792 19004 3409 loc18 loc19 0.749830 0.011390 24410 3409 loc1 loc20 0.263820 0.010855 29737 3409 loc2 loc20 0.310350 0.010956 36709 3409 loc3 loc20 0.413110 0.018705 13729 3409 loc4 loc20 0.505570 0.014782 16663 3409 loc5 loc20 0.389080 0.015602 20929 3409 loc6 loc20 0.673900 0.019699 10224 3409 loc7 loc20 0.099990 0.008664 21174 3409 loc8 loc20 0.834300 0.007177 29356 3409 loc9 loc20 0.105220 0.007928 22782 3409 loc10 loc20 0.346570 0.013984 20553 3409 loc11 loc20 0.379390 0.021202 13302 3409 loc12 loc20 0.376410 0.017127 17411 3409 loc13 loc20 0.363090 0.017562 16243 3409 loc14 loc20 0.198910 0.011883 18305 3409 loc15 loc20 0.589360 0.015435 24475 3409 loc16 loc20 0.833000 0.011274 15546 3409 loc17 loc20 0.724730 0.013138 17253 3409 loc18 loc20 0.671130 0.013836 22234 3409 loc19 loc20 0.000000 0.000000 21047 3409 loc1 loc21 0.995760 0.000523 33070 3409 loc2 loc21 0.907860 0.004654 40434 3409 loc3 loc21 0.192700 0.013262 14655 3409 loc4 loc21 0.519430 0.017374 18349 3409 loc5 loc21 0.091830 0.008212 22409 3409 loc6 loc21 0.561270 0.023494 10571 3409 loc7 loc21 0.144410 0.010218 22940 3409 loc8 loc21 0.165650 0.009435 32040 3409 loc9 loc21 0.179220 0.011302 24557 3409 loc10 loc21 0.987430 0.001755 22299 3409 loc11 loc21 0.374090 0.018588 13498 3409 loc12 loc21 0.313340 0.013646 18605 3409 loc13 loc21 0.238630 0.013580 17938 3409 loc14 loc21 0.265110 0.013604 20003 3409 loc15 loc21 0.748770 0.008798 27468 3409 loc16 loc21 0.392490 0.016288 17037 3409 loc17 loc21 0.123080 0.008477 18772 3409 loc18 loc21 0.940490 0.004550 24540 3409 loc19 loc21 0.909420 0.006243 23425 3409 loc20 loc21 0.300010 0.012730 20819 3409 loc1 loc22 0.083110 0.005603 31895 3409 loc2 loc22 0.649040 0.009135 39523 3409 loc3 loc22 0.699960 0.015478 14340 3409 loc4 loc22 0.692970 0.013195 17442 3409 loc5 loc22 0.106300 0.009760 22402 3409 loc6 loc22 0.173180 0.016297 10693 3409 loc7 loc22 0.181560 0.009652 22367 3409 loc8 loc22 0.521680 0.013362 31298 3409 loc9 loc22 0.769010 0.010944 23903 3409 loc10 loc22 0.243650 0.011069 22065 3409 loc11 loc22 0.027570 0.005710 13985 3409 loc12 loc22 0.035200 0.005352 18654 3409 loc13 loc22 0.625990 0.016655 16983 3409 loc14 loc22 0.380800 0.015594 18994 3409 loc15 loc22 0.691620 0.011594 25925 3409 loc16 loc22 0.709040 0.016228 16420 3409 loc17 loc22 0.270500 0.013422 17976 3409 loc18 loc22 0.541040 0.013921 23434 3409 loc19 loc22 0.862210 0.009649 22214 3409 loc20 loc22 0.216890 0.012787 19776 3409 loc21 loc22 0.000040 0.000040 22274 3409 loc1 loc23 0.461300 0.011363 34296 3409 loc2 loc23 0.926220 0.004059 41366 3409 loc3 loc23 0.037590 0.005905 16519 3409 loc4 loc23 0.861040 0.008226 19740 3409 loc5 loc23 0.909740 0.006631 24285 3409 loc6 loc23 0.129970 0.014705 12533 3409 loc7 loc23 0.093260 0.007566 24859 3409 loc8 loc23 0.330110 0.011295 33381 3409 loc9 loc23 0.578220 0.012529 26477 3409 loc10 loc23 0.630310 0.011424 24154 3409 loc11 loc23 0.291900 0.012653 23714 3409 loc12 loc23 0.931660 0.005012 32033 3409 loc13 loc23 0.744150 0.012870 19470 3409 loc14 loc23 0.648700 0.012023 21560 3409 loc15 loc23 0.003300 0.000958 29347 3409 loc16 loc23 0.175620 0.012580 18736 3409 loc17 loc23 0.231430 0.011925 20128 3409 loc18 loc23 0.751550 0.010399 26162 3409 loc19 loc23 0.087040 0.007239 25382 3409 loc20 loc23 0.973870 0.002765 22531 3409 loc21 loc23 0.084530 0.007370 25060 3409 loc22 loc23 0.114220 0.009581 23750 3409 loc1 loc24 0.958200 0.003027 33498 3409 loc2 loc24 0.720530 0.007873 41572 3409 loc3 loc24 0.076620 0.008087 15868 3409 loc4 loc24 0.171290 0.011257 19217 3409 loc5 loc24 0.975440 0.002813 24006 3409 loc6 loc24 0.442090 0.017047 12231 3409 loc7 loc24 0.563590 0.014280 24583 3409 loc8 loc24 0.245810 0.009496 33458 3409 loc9 loc24 0.882870 0.006017 26179 3409 loc10 loc24 0.602550 0.014699 23904 3409 loc11 loc24 0.760010 0.015478 14641 3409 loc12 loc24 0.358470 0.015414 19295 3409 loc13 loc24 0.889740 0.007956 18866 3409 loc14 loc24 0.028970 0.003720 20652 3409 loc15 loc24 0.402540 0.011979 27577 3409 loc16 loc24 0.705580 0.013459 17934 3409 loc17 loc24 0.859480 0.008196 19413 3409 loc18 loc24 0.487470 0.012915 24989 3409 loc19 loc24 0.020220 0.003153 24206 3409 loc20 loc24 0.080810 0.007088 21810 3409 loc21 loc24 0.482550 0.012897 24351 3409 loc22 loc24 0.298220 0.012299 22802 3409 loc23 loc24 0.000470 0.000305 25488 3409 loc1 loc25 0.999880 0.000050 39262 3409 loc2 loc25 0.951340 0.003078 48080 3409 loc3 loc25 0.993870 0.001316 17779 3409 loc4 loc25 0.143340 0.010343 21646 3409 loc5 loc25 0.260340 0.013490 27457 3409 loc6 loc25 0.594860 0.021507 13041 3409 loc7 loc25 0.043480 0.005821 28320 3409 loc8 loc25 0.329060 0.011592 38469 3409 loc9 loc25 0.399490 0.012554 30018 3409 loc10 loc25 0.846600 0.009597 27213 3409 loc11 loc25 0.432650 0.019606 16596 3409 loc12 loc25 0.160230 0.013210 22529 3409 loc13 loc25 0.726900 0.014113 20721 3409 loc14 loc25 0.979690 0.002174 23694 3409 loc15 loc25 0.985440 0.001581 32520 3409 loc16 loc25 0.981870 0.002910 20287 3409 loc17 loc25 0.903950 0.006517 22272 3409 loc18 loc25 0.587040 0.013389 28761 3409 loc19 loc25 0.562400 0.012849 27464 3409 loc20 loc25 0.593320 0.012962 24709 3409 loc21 loc25 0.469200 0.012884 27436 3409 loc22 loc25 0.307380 0.011435 26454 3409 loc23 loc25 0.633590 0.011693 29710 3409 loc24 loc25 0.550960 0.012859 28111 3409 loc1 loc26 0.963930 0.002244 37935 3409 loc2 loc26 0.111790 0.005485 46709 3409 loc3 loc26 0.977710 0.003195 17896 3409 loc4 loc26 0.829310 0.009800 21885 3409 loc5 loc26 0.084830 0.008813 26376 3409 loc6 loc26 0.349740 0.020841 12429 3409 loc7 loc26 0.256370 0.010422 26835 3409 loc8 loc26 0.593600 0.012110 37006 3409 loc9 loc26 0.107140 0.007327 28772 3409 loc10 loc26 0.275120 0.015148 26190 3409 loc11 loc26 0.719120 0.016241 16461 3409 loc12 loc26 0.885510 0.008057 22215 3409 loc13 loc26 0.091270 0.008327 21526 3409 loc14 loc26 0.302600 0.013196 23870 3409 loc15 loc26 0.142340 0.009095 33092 3409 loc16 loc26 0.922180 0.005986 20717 3409 loc17 loc26 0.779070 0.010178 22722 3409 loc18 loc26 0.602030 0.011643 28888 3409 loc19 loc26 0.049180 0.005259 28194 3409 loc20 loc26 0.354670 0.014468 25403 3409 loc21 loc26 0.352450 0.013961 28268 3409 loc22 loc26 0.128010 0.009111 26727 3409 loc23 loc26 0.193920 0.010895 29915 3409 loc24 loc26 0.459400 0.012312 28491 3409 loc25 loc26 0.009740 0.002380 33084 3409 loc1 loc27 No data 3409 loc2 loc27 No data 3409 loc3 loc27 No data 3409 loc4 loc27 No data 3409 loc5 loc27 No data 3409 loc6 loc27 No data 3409 loc7 loc27 No data 3409 loc8 loc27 No data 3409 loc9 loc27 No data 3409 loc10 loc27 No data 3409 loc11 loc27 No data 3409 loc12 loc27 No data 3409 loc13 loc27 No data 3409 loc14 loc27 No data 3409 loc15 loc27 No data 3409 loc16 loc27 No data 3409 loc17 loc27 No data 3409 loc18 loc27 No data 3409 loc19 loc27 No data 3409 loc20 loc27 No data 3409 loc21 loc27 No data 3409 loc22 loc27 No data 3409 loc23 loc27 No data 3409 loc24 loc27 No data 3409 loc25 loc27 No data 3409 loc26 loc27 No data 3409 loc1 loc28 No data 3409 loc2 loc28 No data 3409 loc3 loc28 No data 3409 loc4 loc28 No data 3409 loc5 loc28 No data 3409 loc6 loc28 No data 3409 loc7 loc28 No data 3409 loc8 loc28 No data 3409 loc9 loc28 No data 3409 loc10 loc28 No data 3409 loc11 loc28 No data 3409 loc12 loc28 No data 3409 loc13 loc28 No data 3409 loc14 loc28 No data 3409 loc15 loc28 No data 3409 loc16 loc28 No data 3409 loc17 loc28 No data 3409 loc18 loc28 No data 3409 loc19 loc28 No data 3409 loc20 loc28 No data 3409 loc21 loc28 No data 3409 loc22 loc28 No data 3409 loc23 loc28 No data 3409 loc24 loc28 No data 3409 loc25 loc28 No data 3409 loc26 loc28 No data 3409 loc27 loc28 No data P-value for each locus pair across all populations (Fisher's method) ----------------------------------------------------- Locus pair Chi2 df P-Value -------------------- -------- --- -------- loc1 & loc2 Infinity 12 Highly sign. loc1 & loc3 5.921216 12 0.920001 loc2 & loc3 21.815879 12 0.039636 loc1 & loc4 13.423221 12 0.339044 loc2 & loc4 16.164020 12 0.183839 loc3 & loc4 Infinity 12 Highly sign. loc1 & loc5 8.011580 12 0.784225 loc2 & loc5 6.018550 12 0.915144 loc3 & loc5 19.500840 12 0.077137 loc4 & loc5 14.990835 12 0.241938 loc1 & loc6 10.322334 12 0.587705 loc2 & loc6 6.613692 12 0.882052 loc3 & loc6 10.416610 12 0.579462 loc4 & loc6 15.098691 12 0.236084 loc5 & loc6 Infinity 12 Highly sign. loc1 & loc7 7.445837 12 0.826801 loc2 & loc7 12.008950 12 0.444961 loc3 & loc7 11.285150 12 0.504652 loc4 & loc7 10.123114 12 0.605161 loc5 & loc7 22.061998 12 0.036831 loc6 & loc7 8.761535 12 0.723152 loc1 & loc8 12.394405 12 0.414547 loc2 & loc8 8.218070 12 0.767865 loc3 & loc8 11.739338 12 0.466834 loc4 & loc8 9.300816 12 0.677045 loc5 & loc8 8.178860 12 0.771002 loc6 & loc8 7.504628 12 0.822546 loc7 & loc8 Infinity 12 Highly sign. loc1 & loc9 10.542576 12 0.568472 loc2 & loc9 3.958575 12 0.984172 loc3 & loc9 12.933734 12 0.373876 loc4 & loc9 8.849048 12 0.715767 loc5 & loc9 19.917247 12 0.068668 loc6 & loc9 13.365150 12 0.343068 loc7 & loc9 3.585286 12 0.989812 loc8 & loc9 14.253777 12 0.284797 loc1 & loc10 14.961231 12 0.243563 loc2 & loc10 16.651917 12 0.163167 loc3 & loc10 9.784841 12 0.634830 loc4 & loc10 8.384317 12 0.754423 loc5 & loc10 10.434930 12 0.577861 loc6 & loc10 2.618007 12 0.997693 loc7 & loc10 5.751868 12 0.928070 loc8 & loc10 5.800818 12 0.925788 loc9 & loc10 Infinity 12 Highly sign. loc1 & loc11 14.038495 12 0.298257 loc2 & loc11 4.732230 12 0.966330 loc3 & loc11 18.132646 12 0.111722 loc4 & loc11 12.548195 12 0.402716 loc5 & loc11 13.292415 12 0.348150 loc6 & loc11 8.868982 12 0.714078 loc7 & loc11 6.244722 12 0.903246 loc8 & loc11 10.125452 12 0.604956 loc9 & loc11 9.852307 12 0.628916 loc10 & loc11 8.789203 12 0.720822 loc1 & loc12 4.408070 12 0.974898 loc2 & loc12 14.859219 12 0.249226 loc3 & loc12 15.595326 12 0.210482 loc4 & loc12 15.311915 12 0.224820 loc5 & loc12 6.727563 12 0.875080 loc6 & loc12 10.246905 12 0.594310 loc7 & loc12 16.304704 12 0.177675 loc8 & loc12 20.257842 12 0.062363 loc9 & loc12 3.701010 12 0.988247 loc10 & loc12 13.546139 12 0.330624 loc11 & loc12 Infinity 12 Highly sign. loc1 & loc13 15.239420 12 0.228604 loc2 & loc13 11.538986 12 0.483377 loc3 & loc13 8.407172 12 0.752557 loc4 & loc13 14.471211 12 0.271635 loc5 & loc13 15.162788 12 0.232655 loc6 & loc13 9.604483 12 0.650615 loc7 & loc13 18.235320 12 0.108730 loc8 & loc13 16.044275 12 0.189217 loc9 & loc13 14.333850 12 0.279899 loc10 & loc13 7.920617 12 0.791303 loc11 & loc13 14.726499 12 0.256735 loc12 & loc13 12.692043 12 0.391816 loc1 & loc14 6.850064 12 0.867361 loc2 & loc14 10.834864 12 0.543121 loc3 & loc14 8.562118 12 0.739806 loc4 & loc14 14.200429 12 0.288093 loc5 & loc14 13.329831 12 0.345530 loc6 & loc14 14.612574 12 0.263310 loc7 & loc14 13.001250 12 0.368950 loc8 & loc14 18.937188 12 0.090056 loc9 & loc14 23.212110 12 0.025978 loc10 & loc14 21.085118 12 0.049148 loc11 & loc14 10.090147 12 0.608052 loc12 & loc14 16.606081 12 0.165026 loc13 & loc14 Infinity 12 Highly sign. loc1 & loc15 14.150283 12 0.291215 loc2 & loc15 17.074922 12 0.146801 loc3 & loc15 28.437378 12 0.004772 loc4 & loc15 7.728572 12 0.805966 loc5 & loc15 9.603988 12 0.650658 loc6 & loc15 6.430521 12 0.892845 loc7 & loc15 6.716526 12 0.875764 loc8 & loc15 6.519777 12 0.887652 loc9 & loc15 8.556556 12 0.740267 loc10 & loc15 4.946401 12 0.959745 loc11 & loc15 8.322577 12 0.759441 loc12 & loc15 13.277197 12 0.349219 loc13 & loc15 7.264740 12 0.839634 loc14 & loc15 7.834959 12 0.797891 loc1 & loc16 15.864728 12 0.197511 loc2 & loc16 17.115133 12 0.145317 loc3 & loc16 19.738374 12 0.072200 loc4 & loc16 16.221199 12 0.181314 loc5 & loc16 12.568710 12 0.401152 loc6 & loc16 14.683372 12 0.259210 loc7 & loc16 16.556586 12 0.167052 loc8 & loc16 6.665532 12 0.878902 loc9 & loc16 5.167709 12 0.952141 loc10 & loc16 9.921366 12 0.622859 loc11 & loc16 10.624700 12 0.561326 loc12 & loc16 11.495475 12 0.487000 loc13 & loc16 8.448644 12 0.749162 loc14 & loc16 8.324199 12 0.759310 loc15 & loc16 Infinity 12 Highly sign. loc1 & loc17 16.176621 12 0.183280 loc2 & loc17 7.095492 12 0.851239 loc3 & loc17 9.017358 12 0.701447 loc4 & loc17 15.722234 12 0.204292 loc5 & loc17 14.710961 12 0.257625 loc6 & loc17 12.421043 12 0.412484 loc7 & loc17 9.608037 12 0.650304 loc8 & loc17 3.809774 12 0.986629 loc9 & loc17 8.748642 12 0.724237 loc10 & loc17 8.698932 12 0.728408 loc11 & loc17 14.621085 12 0.262815 loc12 & loc17 19.357439 12 0.080260 loc13 & loc17 12.179123 12 0.431403 loc14 & loc17 9.034931 12 0.699944 loc15 & loc17 22.275771 12 0.034543 loc16 & loc17 19.879228 12 0.069405 loc1 & loc18 10.877881 12 0.539412 loc2 & loc18 7.468029 12 0.825200 loc3 & loc18 6.590655 12 0.883438 loc4 & loc18 12.968209 12 0.371356 loc5 & loc18 Infinity 12 Highly sign. loc6 & loc18 10.450470 12 0.576505 loc7 & loc18 8.839404 12 0.716583 loc8 & loc18 7.551812 12 0.819102 loc9 & loc18 13.399419 12 0.340690 loc10 & loc18 15.076025 12 0.237305 loc11 & loc18 12.630746 12 0.396441 loc12 & loc18 19.074277 12 0.086752 loc13 & loc18 12.890916 12 0.377019 loc14 & loc18 14.580959 12 0.265156 loc15 & loc18 18.517621 12 0.100854 loc16 & loc18 14.588596 12 0.264709 loc17 & loc18 Infinity 12 Highly sign. loc1 & loc19 12.870446 12 0.378527 loc2 & loc19 17.505309 12 0.131557 loc3 & loc19 5.661985 12 0.932154 loc4 & loc19 10.585339 12 0.564749 loc5 & loc19 10.123258 12 0.605148 loc6 & loc19 6.995362 12 0.857920 loc7 & loc19 30.374720 12 0.002452 loc8 & loc19 16.140547 12 0.184883 loc9 & loc19 10.315674 12 0.588288 loc10 & loc19 14.288934 12 0.282639 loc11 & loc19 12.397216 12 0.414329 loc12 & loc19 17.819591 12 0.121279 loc13 & loc19 10.099585 12 0.607224 loc14 & loc19 26.776209 12 0.008321 loc15 & loc19 24.026890 12 0.020170 loc16 & loc19 12.824642 12 0.381914 loc17 & loc19 13.367518 12 0.342903 loc18 & loc19 11.365156 12 0.497911 loc1 & loc20 7.195727 12 0.844413 loc2 & loc20 8.450080 12 0.749044 loc3 & loc20 9.411504 12 0.667438 loc4 & loc20 17.843996 12 0.120510 loc5 & loc20 11.568588 12 0.480918 loc6 & loc20 15.189680 12 0.231227 loc7 & loc20 24.893208 12 0.015337 loc8 & loc20 4.793165 12 0.964533 loc9 & loc20 14.197747 12 0.288259 loc10 & loc20 9.031504 12 0.700237 loc11 & loc20 10.843045 12 0.542416 loc12 & loc20 5.828031 12 0.924501 loc13 & loc20 5.356553 12 0.944998 loc14 & loc20 15.330114 12 0.223878 loc15 & loc20 9.154085 12 0.689716 loc16 & loc20 13.163164 12 0.357294 loc17 & loc20 17.179102 12 0.142983 loc18 & loc20 11.730113 12 0.467591 loc19 & loc20 Infinity 12 Highly sign. loc1 & loc21 9.513149 12 0.658588 loc2 & loc21 7.233620 12 0.841797 loc3 & loc21 16.352399 12 0.175623 loc4 & loc21 6.199747 12 0.905680 loc5 & loc21 11.645387 12 0.474563 loc6 & loc21 8.095995 12 0.777584 loc7 & loc21 13.150074 12 0.358228 loc8 & loc21 11.325164 12 0.501277 loc9 & loc21 12.519087 12 0.404941 loc10 & loc21 12.560200 12 0.401800 loc11 & loc21 17.557162 12 0.129813 loc12 & loc21 7.208331 12 0.843545 loc13 & loc21 13.785713 12 0.314601 loc14 & loc21 19.287575 12 0.081821 loc15 & loc21 12.978933 12 0.370574 loc16 & loc21 16.791140 12 0.157624 loc17 & loc21 8.000163 12 0.785118 loc18 & loc21 21.207543 12 0.047423 loc19 & loc21 10.688879 12 0.555753 loc20 & loc21 16.390037 12 0.174018 loc1 & loc22 20.987695 12 0.050561 loc2 & loc22 16.489393 12 0.169835 loc3 & loc22 16.750354 12 0.159232 loc4 & loc22 16.274680 12 0.178977 loc5 & loc22 13.011215 12 0.368226 loc6 & loc22 13.629449 12 0.324994 loc7 & loc22 25.130386 12 0.014217 loc8 & loc22 4.168012 12 0.980210 loc9 & loc22 4.834113 12 0.963291 loc10 & loc22 10.362745 12 0.584170 loc11 & loc22 13.001613 12 0.368923 loc12 & loc22 17.732501 12 0.124057 loc13 & loc22 10.378793 12 0.582767 loc14 & loc22 12.733086 12 0.388736 loc15 & loc22 10.275131 12 0.591837 loc16 & loc22 12.183884 12 0.431027 loc17 & loc22 8.529742 12 0.742485 loc18 & loc22 7.387286 12 0.830996 loc19 & loc22 11.697770 12 0.470247 loc20 & loc22 8.928905 12 0.708991 loc21 & loc22 Infinity 12 Highly sign. loc1 & loc23 15.719893 12 0.204405 loc2 & loc23 14.352185 12 0.278786 loc3 & loc23 12.871963 12 0.378415 loc4 & loc23 16.010808 12 0.190741 loc5 & loc23 10.927471 12 0.535145 loc6 & loc23 9.275700 12 0.679219 loc7 & loc23 9.907526 12 0.624073 loc8 & loc23 8.836279 12 0.716847 loc9 & loc23 6.444337 12 0.892049 loc10 & loc23 15.967922 12 0.192710 loc11 & loc23 17.013562 12 0.149088 loc12 & loc23 12.393794 12 0.414594 loc13 & loc23 17.772960 12 0.122760 loc14 & loc23 17.087334 12 0.146342 loc15 & loc23 19.002278 12 0.088474 loc16 & loc23 11.260039 12 0.506775 loc17 & loc23 11.509326 12 0.485845 loc18 & loc23 8.833567 12 0.717076 loc19 & loc23 11.986145 12 0.446793 loc20 & loc23 6.505911 12 0.888467 loc21 & loc23 13.012280 12 0.368149 loc22 & loc23 16.094842 12 0.186931 loc1 & loc24 9.019821 12 0.701237 loc2 & loc24 10.992551 12 0.529557 loc3 & loc24 15.618899 12 0.209321 loc4 & loc24 6.582301 12 0.883939 loc5 & loc24 12.400652 12 0.414062 loc6 & loc24 8.473917 12 0.747086 loc7 & loc24 13.178221 12 0.356221 loc8 & loc24 6.986042 12 0.858535 loc9 & loc24 16.910456 12 0.152997 loc10 & loc24 12.904674 12 0.376007 loc11 & loc24 3.709491 12 0.988127 loc12 & loc24 9.261686 12 0.680431 loc13 & loc24 12.607752 12 0.398183 loc14 & loc24 15.563686 12 0.212047 loc15 & loc24 9.164612 12 0.688810 loc16 & loc24 11.673428 12 0.472250 loc17 & loc24 8.044178 12 0.781669 loc18 & loc24 4.108737 12 0.981393 loc19 & loc24 18.410347 12 0.103787 loc20 & loc24 14.327610 12 0.280279 loc21 & loc24 8.150682 12 0.773247 loc22 & loc24 13.640079 12 0.324280 loc23 & loc24 Infinity 12 Highly sign. loc1 & loc25 8.571211 12 0.739052 loc2 & loc25 6.029565 12 0.914584 loc3 & loc25 10.054111 12 0.611213 loc4 & loc25 14.542711 12 0.267401 loc5 & loc25 18.962439 12 0.089439 loc6 & loc25 14.448951 12 0.272962 loc7 & loc25 19.751552 12 0.071934 loc8 & loc25 16.358742 12 0.175352 loc9 & loc25 8.800978 12 0.719829 loc10 & loc25 9.127104 12 0.692037 loc11 & loc25 14.208949 12 0.287565 loc12 & loc25 16.233482 12 0.180775 loc13 & loc25 23.960319 12 0.020595 loc14 & loc25 7.541114 12 0.819885 loc15 & loc25 6.356724 12 0.897043 loc16 & loc25 2.234118 12 0.998954 loc17 & loc25 19.933620 12 0.068352 loc18 & loc25 9.809183 12 0.632697 loc19 & loc25 12.366061 12 0.416746 loc20 & loc25 9.526033 12 0.657464 loc21 & loc25 11.416991 12 0.493560 loc22 & loc25 10.529118 12 0.569644 loc23 & loc25 14.971803 12 0.242982 loc24 & loc25 13.202705 12 0.354481 loc1 & loc26 7.625628 12 0.813660 loc2 & loc26 21.869872 12 0.039004 loc3 & loc26 17.225712 12 0.141302 loc4 & loc26 25.897750 12 0.011097 loc5 & loc26 14.678674 12 0.259481 loc6 & loc26 11.094883 12 0.520805 loc7 & loc26 8.768415 12 0.722573 loc8 & loc26 4.458624 12 0.973669 loc9 & loc26 10.279086 12 0.591491 loc10 & loc26 13.767590 12 0.315795 loc11 & loc26 9.181035 12 0.687395 loc12 & loc26 17.382070 12 0.135781 loc13 & loc26 16.277766 12 0.178843 loc14 & loc26 8.939749 12 0.708068 loc15 & loc26 9.743509 12 0.638451 loc16 & loc26 6.577729 12 0.884212 loc17 & loc26 5.095162 12 0.954725 loc18 & loc26 8.639814 12 0.733348 loc19 & loc26 12.788183 12 0.384623 loc20 & loc26 15.378953 12 0.221364 loc21 & loc26 10.065670 12 0.610199 loc22 & loc26 9.573501 12 0.653321 loc23 & loc26 18.805331 12 0.093336 loc24 & loc26 14.131871 12 0.292367 loc25 & loc26 Infinity 12 Highly sign. loc1 & loc27 5.187745 6 0.519969 loc2 & loc27 5.894116 6 0.435155 loc3 & loc27 1.715813 6 0.943894 loc4 & loc27 7.478248 6 0.278871 loc5 & loc27 2.978684 6 0.811517 loc6 & loc27 4.083371 6 0.665395 loc7 & loc27 1.176305 6 0.978039 loc8 & loc27 5.324869 6 0.502871 loc9 & loc27 3.288510 6 0.771861 loc10 & loc27 9.757775 6 0.135230 loc11 & loc27 4.567328 6 0.600375 loc12 & loc27 3.814469 6 0.701767 loc13 & loc27 4.920237 6 0.554083 loc14 & loc27 4.531232 6 0.605177 loc15 & loc27 6.018295 6 0.421144 loc16 & loc27 5.227409 6 0.514995 loc17 & loc27 13.476932 6 0.036057 loc18 & loc27 13.686394 6 0.033342 loc19 & loc27 1.549886 6 0.956112 loc20 & loc27 1.732354 6 0.942596 loc21 & loc27 4.022912 6 0.673576 loc22 & loc27 5.116227 6 0.528995 loc23 & loc27 0.799419 6 0.992089 loc24 & loc27 4.918245 6 0.554341 loc25 & loc27 12.806709 6 0.046210 loc26 & loc27 2.309305 6 0.889169 loc1 & loc28 5.654160 6 0.463024 loc2 & loc28 2.971559 6 0.812408 loc3 & loc28 1.892889 6 0.929281 loc4 & loc28 5.798041 6 0.446190 loc5 & loc28 4.508665 6 0.608184 loc6 & loc28 2.907018 6 0.820423 loc7 & loc28 3.113859 6 0.794427 loc8 & loc28 10.496024 6 0.105258 loc9 & loc28 7.312686 6 0.292896 loc10 & loc28 1.914206 6 0.927417 loc11 & loc28 5.074409 6 0.534306 loc12 & loc28 5.262237 6 0.510646 loc13 & loc28 14.077976 6 0.028777 loc14 & loc28 5.450473 6 0.487463 loc15 & loc28 3.653539 6 0.723442 loc16 & loc28 4.396873 6 0.623133 loc17 & loc28 5.740401 6 0.452890 loc18 & loc28 6.588400 6 0.360593 loc19 & loc28 5.197947 6 0.518687 loc20 & loc28 4.357611 6 0.628402 loc21 & loc28 3.015187 6 0.806938 loc22 & loc28 2.136117 6 0.906764 loc23 & loc28 2.576138 6 0.859851 loc24 & loc28 1.703921 6 0.944818 loc25 & loc28 3.096945 6 0.796585 loc26 & loc28 4.618758 6 0.593553 loc27 & loc28 Infinity 6 Highly sign. Normal ending. Results from GENEPOP -------------------------------------------------------------------------------- Fri Aug 12 13:12:50 WST 2011 Genepop version 4.0.10, Genic differentiation for each population pair (exact G test) File: 131250 (African American) Number of populations detected : 6 Number of loci detected : 28 Markov chain parameters Dememorisation : 1000 Batches : 100 Iterations per batch : 1000 Locus: loc1 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 12 13 14 15 16 17 18 19 Total B0800 3 5 49 87 53 13 0 0 210 C202 0 1 55 77 51 15 4 0 203 H462 0 1 32 125 44 5 1 1 209 2249 0 0 23 76 48 9 1 0 157 6567 2 6 23 103 46 14 0 0 194 3409 0 0 9 39 26 6 0 0 80 Total: 5 13 191 507 268 62 6 1 1053 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc1 C202 & B0800 0.05218 0.00381 67911 loc1 H462 & B0800 0.00031 0.00021 56691 loc1 H462 & C202 0.00002 0.00001 59939 loc1 2249 & B0800 0.01700 0.00229 60764 loc1 2249 & C202 0.02688 0.00380 65099 loc1 2249 & H462 0.13185 0.00969 52744 loc1 6567 & B0800 0.05656 0.00401 75860 loc1 6567 & C202 0.00000 0.00000 65929 loc1 6567 & H462 0.01650 0.00343 54651 loc1 6567 & 2249 0.04289 0.00400 59758 loc1 3409 & B0800 0.05186 0.00459 66018 loc1 3409 & C202 0.02345 0.00326 57362 loc1 3409 & H462 0.12428 0.00786 41111 loc1 3409 & 2249 0.90152 0.00391 61646 loc1 3409 & 6567 0.23911 0.00833 64834 Locus: loc2 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 14 15 16 17 18 19 Total B0800 2 35 76 71 23 3 210 C202 2 23 43 71 62 2 203 H462 1 53 67 48 34 6 209 2249 1 25 58 53 19 1 157 6567 3 29 73 68 18 3 194 3409 0 11 25 26 18 0 80 Total: 9 176 342 337 174 15 1053 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc2 C202 & B0800 0.00002 0.00002 73178 loc2 H462 & B0800 0.04484 0.00450 74343 loc2 H462 & C202 0.00000 0.00000 74011 loc2 2249 & B0800 0.98094 0.00141 69789 loc2 2249 & C202 0.00024 0.00014 68942 loc2 2249 & H462 0.04694 0.00445 70075 loc2 6567 & B0800 0.97533 0.00170 74167 loc2 6567 & C202 0.00000 0.00000 73822 loc2 6567 & H462 0.00687 0.00182 74975 loc2 6567 & 2249 0.85526 0.00627 71252 loc2 3409 & B0800 0.12691 0.00708 62916 loc2 3409 & C202 0.31362 0.01002 61252 loc2 3409 & H462 0.04058 0.00379 60327 loc2 3409 & 2249 0.36671 0.00983 52941 loc2 3409 & 6567 0.05174 0.00442 65224 Locus: loc3 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 11 13 14 15 16 17 18 19 Total B0800 1 2 23 77 47 25 5 0 180 C202 0 2 39 37 50 41 23 4 196 H462 1 0 24 29 95 36 17 1 203 2249 3 9 20 37 58 26 8 1 162 6567 2 4 36 91 76 23 9 3 244 3409 1 1 14 22 29 14 3 1 85 Total: 8 18 156 293 355 165 65 10 1070 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc3 C202 & B0800 0.00000 0.00000 64797 loc3 H462 & B0800 0.00000 0.00000 58931 loc3 H462 & C202 0.00033 0.00018 63377 loc3 2249 & B0800 0.00110 0.00031 66216 loc3 2249 & C202 0.00112 0.00062 71431 loc3 2249 & H462 0.00332 0.00131 68044 loc3 6567 & B0800 0.46868 0.00972 66983 loc3 6567 & C202 0.00000 0.00000 69578 loc3 6567 & H462 0.00000 0.00000 68098 loc3 6567 & 2249 0.02665 0.00355 71615 loc3 3409 & B0800 0.31594 0.01142 54339 loc3 3409 & C202 0.12450 0.00738 59316 loc3 3409 & H462 0.07935 0.00601 54104 loc3 3409 & 2249 0.76646 0.00718 65026 loc3 3409 & 6567 0.67427 0.00795 62819 Locus: loc4 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 14 15 16 17 18 19 20 21 Total B0800 1 8 50 41 44 26 10 0 180 C202 1 7 29 62 64 29 4 0 196 H462 1 2 51 54 62 28 5 0 203 2249 0 12 27 41 51 22 9 0 162 6567 0 20 66 66 55 23 11 3 244 3409 1 2 21 31 20 7 3 0 85 Total: 4 51 244 295 296 135 42 3 1070 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc4 C202 & B0800 0.01970 0.00281 72195 loc4 H462 & B0800 0.21568 0.01095 71299 loc4 H462 & C202 0.15337 0.00782 70112 loc4 2249 & B0800 0.17703 0.01139 71293 loc4 2249 & C202 0.23824 0.01148 70159 loc4 2249 & H462 0.01243 0.00416 69503 loc4 6567 & B0800 0.17960 0.00948 67077 loc4 6567 & C202 0.00061 0.00031 66783 loc4 6567 & H462 0.00125 0.00094 66974 loc4 6567 & 2249 0.05895 0.00504 75603 loc4 3409 & B0800 0.32555 0.01061 68645 loc4 3409 & C202 0.26402 0.00934 66021 loc4 3409 & H462 0.52564 0.00958 63626 loc4 3409 & 2249 0.05411 0.00451 65274 loc4 3409 & 6567 0.18393 0.00878 59632 Locus: loc5 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 17 18 19 20 21 22 23 24 25 26 27 30 Total B0800 1 6 18 24 35 51 26 16 3 0 0 0 180 C202 0 12 20 50 43 38 22 9 2 0 0 0 196 H462 0 1 32 24 43 44 26 20 9 4 0 0 203 2249 1 7 18 19 30 30 29 18 2 1 1 1 157 6567 2 9 26 18 21 57 28 18 8 2 1 4 194 3409 0 2 8 11 14 21 11 10 3 0 0 0 80 Total: 4 37 122 146 186 241 142 91 27 7 2 5 1010 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc5 C202 & B0800 0.03626 0.00398 70105 loc5 H462 & B0800 0.04575 0.00555 68149 loc5 H462 & C202 0.00000 0.00000 76075 loc5 2249 & B0800 0.75152 0.01176 56759 loc5 2249 & C202 0.00757 0.00253 54891 loc5 2249 & H462 0.05688 0.00623 58488 loc5 6567 & B0800 0.08740 0.00672 62486 loc5 6567 & C202 0.00000 0.00000 61807 loc5 6567 & H462 0.00499 0.00121 64091 loc5 6567 & 2249 0.31510 0.01155 65094 loc5 3409 & B0800 0.97731 0.00199 63985 loc5 3409 & C202 0.05653 0.00460 73446 loc5 3409 & H462 0.56439 0.01073 68147 loc5 3409 & 2249 0.91230 0.00517 49027 loc5 3409 & 6567 0.55458 0.01044 55755 Locus: loc6 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 19 20 21 22 23 24 25 26 27 28 29 30 31 Total B0800 2 2 10 32 19 51 33 13 8 6 2 2 0 180 C202 2 8 25 40 40 45 25 7 4 0 0 0 0 196 H462 0 6 11 30 34 31 47 30 13 1 0 0 0 203 2249 0 4 6 16 28 45 28 9 15 3 2 1 0 157 6567 3 0 8 16 48 40 37 14 19 6 3 0 0 194 3409 1 4 2 6 15 23 14 7 3 2 1 1 1 80 Total: 8 24 62 140 184 235 184 80 62 18 8 4 1 1010 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc6 C202 & B0800 0.00004 0.00004 64892 loc6 H462 & B0800 0.00040 0.00017 63539 loc6 H462 & C202 0.00000 0.00000 67755 loc6 2249 & B0800 0.23989 0.00890 65559 loc6 2249 & C202 0.00000 0.00000 60489 loc6 2249 & H462 0.00402 0.00097 64274 loc6 6567 & B0800 0.00265 0.00134 65602 loc6 6567 & C202 0.00000 0.00000 70407 loc6 6567 & H462 0.00019 0.00012 69456 loc6 6567 & 2249 0.16676 0.01035 63500 loc6 3409 & B0800 0.37459 0.01124 56461 loc6 3409 & C202 0.00239 0.00122 48136 loc6 3409 & H462 0.02087 0.00408 46800 loc6 3409 & 2249 0.80339 0.00840 53467 loc6 3409 & 6567 0.06840 0.00506 53406 Locus: loc7 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 14 15 16 Total B0800 1 2 9 12 34 59 50 13 0 180 C202 7 4 37 21 39 64 21 3 0 196 H462 1 1 36 20 37 74 28 5 1 203 2249 0 1 7 15 34 38 49 11 2 157 6567 0 3 5 12 40 55 59 18 2 194 3409 1 0 8 12 20 21 13 5 0 80 Total: 10 11 102 92 204 311 220 55 5 1010 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc7 C202 & B0800 0.00000 0.00000 75970 loc7 H462 & B0800 0.00005 0.00005 62457 loc7 H462 & C202 0.29960 0.01188 67134 loc7 2249 & B0800 0.54248 0.01250 61604 loc7 2249 & C202 0.00000 0.00000 68909 loc7 2249 & H462 0.00000 0.00000 61889 loc7 6567 & B0800 0.65176 0.01129 63181 loc7 6567 & C202 0.00000 0.00000 70404 loc7 6567 & H462 0.00000 0.00000 65363 loc7 6567 & 2249 0.80070 0.00770 71420 loc7 3409 & B0800 0.10116 0.00665 63939 loc7 3409 & C202 0.05395 0.00409 69760 loc7 3409 & H462 0.26156 0.01141 51228 loc7 3409 & 2249 0.10714 0.00765 53549 loc7 3409 & 6567 0.00899 0.00221 56230 Locus: loc8 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 10 11 12 13 14 15 16 17 18 Total B0800 0 1 5 21 70 64 16 3 0 180 C202 3 2 18 69 58 40 5 1 0 196 H462 2 5 12 58 72 42 9 3 0 203 2249 0 1 7 21 57 47 17 7 0 157 6567 0 0 4 25 66 67 29 2 1 194 3409 0 0 5 16 27 23 9 0 0 80 Total: 5 9 51 210 350 283 85 16 1 1010 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc8 C202 & B0800 0.00000 0.00000 66432 loc8 H462 & B0800 0.00000 0.00000 67543 loc8 H462 & C202 0.44541 0.01351 70449 loc8 2249 & B0800 0.71304 0.00918 69913 loc8 2249 & C202 0.00000 0.00000 68085 loc8 2249 & H462 0.00053 0.00019 69050 loc8 6567 & B0800 0.55235 0.01340 59529 loc8 6567 & C202 0.00000 0.00000 58627 loc8 6567 & H462 0.00000 0.00000 61164 loc8 6567 & 2249 0.20619 0.01115 60723 loc8 3409 & B0800 0.21964 0.00830 58270 loc8 3409 & C202 0.00849 0.00161 54335 loc8 3409 & H462 0.07565 0.00451 61185 loc8 3409 & 2249 0.25145 0.00894 62927 loc8 3409 & 6567 0.30976 0.01056 56286 Locus: loc9 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 24 26 27 28 29 30 31 32 33 Total B0800 1 1 22 65 48 23 16 1 2 179 C202 2 0 18 56 53 51 11 5 0 196 H462 1 0 4 27 66 80 21 4 0 203 2249 2 0 21 57 28 31 10 6 2 157 6567 1 0 25 84 40 32 7 4 1 194 3409 0 0 10 30 20 12 6 2 0 80 Total: 7 1 100 319 255 229 71 22 5 1009 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc9 C202 & B0800 0.01256 0.00251 60569 loc9 H462 & B0800 0.00000 0.00000 58513 loc9 H462 & C202 0.00003 0.00003 73756 loc9 2249 & B0800 0.18180 0.00920 62867 loc9 2249 & C202 0.14667 0.00761 68144 loc9 2249 & H462 0.00000 0.00000 67504 loc9 6567 & B0800 0.26014 0.01328 59937 loc9 6567 & C202 0.03194 0.00395 65911 loc9 6567 & H462 0.00000 0.00000 64128 loc9 6567 & 2249 0.68127 0.00870 68442 loc9 3409 & B0800 0.90226 0.00416 49489 loc9 3409 & C202 0.37142 0.00986 67176 loc9 3409 & H462 0.00000 0.00000 60775 loc9 3409 & 2249 0.68209 0.00805 62807 loc9 3409 & 6567 0.84944 0.00672 52838 Locus: loc10 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 27 28 29 30 31 32 33 34 35 36 37 Total B0800 0 12 21 44 44 27 13 4 10 2 2 179 C202 0 9 18 55 56 45 12 0 1 0 0 196 H462 0 1 18 67 42 56 17 2 0 0 0 203 2249 1 12 27 29 36 31 11 3 7 0 0 157 6567 0 22 31 39 37 27 13 4 16 4 1 194 3409 0 6 13 18 15 14 9 3 2 0 0 80 Total: 1 62 128 252 230 200 75 16 36 6 3 1009 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc10 C202 & B0800 0.00229 0.00081 64988 loc10 H462 & B0800 0.00000 0.00000 65077 loc10 H462 & C202 0.01960 0.00248 64557 loc10 2249 & B0800 0.46868 0.01281 61545 loc10 2249 & C202 0.00286 0.00075 66123 loc10 2249 & H462 0.00000 0.00000 66701 loc10 6567 & B0800 0.61531 0.01135 72674 loc10 6567 & C202 0.00000 0.00000 66517 loc10 6567 & H462 0.00000 0.00000 67775 loc10 6567 & 2249 0.24706 0.01175 62608 loc10 3409 & B0800 0.66502 0.00939 63419 loc10 3409 & C202 0.02022 0.00313 66257 loc10 3409 & H462 0.00060 0.00025 64865 loc10 3409 & 2249 0.89971 0.00468 64239 loc10 3409 & 6567 0.38816 0.01082 62496 Locus: loc11 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 10 11 12 13 14 15 16 17 18 19 20 21 22 Total B0800 1 3 20 19 19 42 38 25 11 2 0 0 0 180 C202 5 4 44 35 47 27 14 11 7 2 0 0 0 196 H462 2 5 37 56 48 24 15 10 3 0 0 0 3 203 2249 3 3 14 16 12 39 24 25 12 6 2 1 0 157 6567 0 3 17 10 16 43 52 33 11 7 2 0 0 194 3409 0 4 12 14 10 13 16 3 1 3 1 1 0 78 Total: 11 22 144 150 152 188 159 107 45 20 5 2 3 1008 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc11 C202 & B0800 0.00000 0.00000 73461 loc11 H462 & B0800 0.00000 0.00000 66563 loc11 H462 & C202 0.15005 0.00814 67240 loc11 2249 & B0800 0.48465 0.01310 63068 loc11 2249 & C202 0.00000 0.00000 64896 loc11 2249 & H462 0.00000 0.00000 61869 loc11 6567 & B0800 0.27252 0.01279 65707 loc11 6567 & C202 0.00000 0.00000 70101 loc11 6567 & H462 0.00000 0.00000 65116 loc11 6567 & 2249 0.20590 0.01077 65093 loc11 3409 & B0800 0.01506 0.00226 51967 loc11 3409 & C202 0.00447 0.00138 55092 loc11 3409 & H462 0.00077 0.00051 49277 loc11 3409 & 2249 0.01580 0.00238 62650 loc11 3409 & 6567 0.00047 0.00023 61124 Locus: loc12 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Total B0800 0 1 3 4 18 30 34 36 26 20 4 2 2 0 180 C202 1 6 13 21 23 28 50 29 12 10 2 1 0 0 196 H462 0 6 13 21 32 32 46 18 15 7 8 2 3 0 203 2249 0 1 1 2 11 29 33 28 24 13 7 8 0 0 157 6567 0 0 2 1 13 21 40 34 30 29 15 6 2 1 194 3409 0 1 3 7 11 17 5 8 11 10 5 0 0 0 78 Total: 1 15 35 56 108 157 208 153 118 89 41 19 7 1 1008 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc12 C202 & B0800 0.00028 0.00022 63793 loc12 H462 & B0800 0.00000 0.00000 72557 loc12 H462 & C202 0.31488 0.01247 66777 loc12 2249 & B0800 0.47428 0.01242 64373 loc12 2249 & C202 0.00000 0.00000 69210 loc12 2249 & H462 0.00000 0.00000 72454 loc12 6567 & B0800 0.17965 0.01320 61791 loc12 6567 & C202 0.00000 0.00000 62551 loc12 6567 & H462 0.00000 0.00000 69042 loc12 6567 & 2249 0.34026 0.01315 58392 loc12 3409 & B0800 0.01846 0.00231 59953 loc12 3409 & C202 0.00082 0.00031 58055 loc12 3409 & H462 0.01014 0.00240 64838 loc12 3409 & 2249 0.00127 0.00062 65596 loc12 3409 & 6567 0.00000 0.00000 54186 Locus: loc13 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 7 8 9 10 11 12 13 16 Total B0800 1 18 5 22 72 50 11 1 180 C202 0 0 12 18 117 42 6 0 195 H462 25 1 19 22 103 32 1 0 203 2249 0 22 3 16 58 53 10 0 162 6567 0 24 5 26 80 88 21 0 244 3409 2 4 5 23 31 19 1 0 85 Total: 28 69 49 127 461 284 50 1 1069 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc13 C202 & B0800 0.00000 0.00000 61965 loc13 H462 & B0800 0.00000 0.00000 70087 loc13 H462 & C202 0.00000 0.00000 68314 loc13 2249 & B0800 0.78293 0.00797 61564 loc13 2249 & C202 0.00000 0.00000 79415 loc13 2249 & H462 0.00000 0.00000 79109 loc13 6567 & B0800 0.32675 0.01560 61990 loc13 6567 & C202 0.00000 0.00000 81578 loc13 6567 & H462 0.00000 0.00000 81261 loc13 6567 & 2249 0.76481 0.00794 79836 loc13 3409 & B0800 0.01596 0.00209 59436 loc13 3409 & C202 0.00000 0.00000 61911 loc13 3409 & H462 0.00013 0.00009 66181 loc13 3409 & 2249 0.00003 0.00003 67884 loc13 3409 & 6567 0.00000 0.00000 66778 Locus: loc14 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 14 15 16 Total B0800 0 0 1 22 78 77 2 0 0 180 C202 0 0 1 43 96 51 3 1 0 195 H462 0 3 5 68 86 38 2 1 0 203 2249 1 0 3 21 67 63 5 2 0 162 6567 2 0 1 20 107 104 7 3 0 244 3409 0 0 3 19 36 22 4 0 1 85 Total: 3 3 14 193 470 355 23 7 1 1069 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc14 C202 & B0800 0.01331 0.00284 57451 loc14 H462 & B0800 0.00000 0.00000 57992 loc14 H462 & C202 0.03321 0.00346 61097 loc14 2249 & B0800 0.36278 0.01278 56064 loc14 2249 & C202 0.02758 0.00229 58453 loc14 2249 & H462 0.00000 0.00000 57747 loc14 6567 & B0800 0.28758 0.00996 58011 loc14 6567 & C202 0.00011 0.00009 59471 loc14 6567 & H462 0.00000 0.00000 60644 loc14 6567 & 2249 0.65756 0.00954 64315 loc14 3409 & B0800 0.00712 0.00133 55522 loc14 3409 & C202 0.20135 0.00964 47661 loc14 3409 & H462 0.09160 0.00751 47463 loc14 3409 & 2249 0.15863 0.00855 48939 loc14 3409 & 6567 0.00114 0.00074 47677 Locus: loc15 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 7 8 9 10 11 12 13 14 Total B0800 0 12 10 17 66 70 4 0 179 C202 0 39 24 15 75 40 3 0 196 H462 0 26 71 26 44 27 7 2 203 2249 1 9 9 7 70 57 8 1 162 6567 1 10 11 10 111 91 7 3 244 3409 0 8 7 7 33 23 6 0 84 Total: 2 104 132 82 399 308 35 6 1068 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc15 C202 & B0800 0.00002 0.00002 79675 loc15 H462 & B0800 0.00000 0.00000 73103 loc15 H462 & C202 0.00000 0.00000 72823 loc15 2249 & B0800 0.26884 0.01408 61325 loc15 2249 & C202 0.00000 0.00000 62090 loc15 2249 & H462 0.00000 0.00000 66760 loc15 6567 & B0800 0.09121 0.00670 63854 loc15 6567 & C202 0.00000 0.00000 65843 loc15 6567 & H462 0.00000 0.00000 68678 loc15 6567 & 2249 0.94325 0.00350 66852 loc15 3409 & B0800 0.24270 0.00820 75590 loc15 3409 & C202 0.05076 0.00374 77247 loc15 3409 & H462 0.00000 0.00000 70303 loc15 3409 & 2249 0.55118 0.00994 55540 loc15 3409 & 6567 0.06352 0.00443 56897 Locus: loc16 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 14 15 Total B0800 1 0 1 19 103 41 13 1 179 C202 0 6 5 50 81 40 14 0 196 H462 1 18 15 38 61 49 21 0 203 2249 0 1 1 29 71 44 16 0 162 6567 0 1 2 24 131 63 23 0 244 3409 1 1 2 14 31 21 14 0 84 Total: 3 27 26 174 478 258 101 1 1068 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc16 C202 & B0800 0.00083 0.00083 58413 loc16 H462 & B0800 0.00000 0.00000 64258 loc16 H462 & C202 0.00537 0.00160 71958 loc16 2249 & B0800 0.13995 0.01188 49919 loc16 2249 & C202 0.07711 0.00541 74827 loc16 2249 & H462 0.00000 0.00000 70065 loc16 6567 & B0800 0.78312 0.01122 50599 loc16 6567 & C202 0.00000 0.00000 76218 loc16 6567 & H462 0.00000 0.00000 71086 loc16 6567 & 2249 0.30843 0.01075 65535 loc16 3409 & B0800 0.02370 0.00323 47248 loc16 3409 & C202 0.09740 0.00632 60464 loc16 3409 & H462 0.04956 0.00437 69724 loc16 3409 & 2249 0.50196 0.01041 54296 loc16 3409 & 6567 0.03940 0.00357 51531 Locus: loc17 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 6 7 8 9 10 11 12 13 Total B0800 0 3 62 54 69 20 2 0 210 C202 1 7 57 47 54 29 7 1 203 H462 1 9 37 16 91 46 9 0 209 2249 0 4 42 32 60 22 2 0 162 6567 2 3 84 52 76 23 4 0 244 3409 0 1 28 15 32 7 1 0 84 Total: 4 27 310 216 382 147 25 1 1112 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc17 C202 & B0800 0.12488 0.01108 61842 loc17 H462 & B0800 0.00000 0.00000 69869 loc17 H462 & C202 0.00000 0.00000 65090 loc17 2249 & B0800 0.54468 0.01084 73870 loc17 2249 & C202 0.37163 0.01370 61018 loc17 2249 & H462 0.00124 0.00082 68685 loc17 6567 & B0800 0.66354 0.00971 67684 loc17 6567 & C202 0.21073 0.01178 64824 loc17 6567 & H462 0.00000 0.00000 74077 loc17 6567 & 2249 0.31630 0.01257 67862 loc17 3409 & B0800 0.84301 0.00453 66105 loc17 3409 & C202 0.26944 0.01053 52871 loc17 3409 & H462 0.00029 0.00024 61936 loc17 3409 & 2249 0.74856 0.00664 68362 loc17 3409 & 6567 0.91118 0.00371 60155 Locus: loc18 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 14 Total B0800 11 12 67 74 36 8 2 210 C202 9 13 64 53 50 11 3 203 H462 4 4 37 75 71 16 2 209 2249 7 10 49 50 38 8 0 162 6567 13 16 93 67 46 6 3 244 3409 7 4 24 30 16 3 0 84 Total: 51 59 334 349 257 52 10 1112 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc18 C202 & B0800 0.35796 0.01104 77272 loc18 H462 & B0800 0.00002 0.00002 75220 loc18 H462 & C202 0.00165 0.00059 76172 loc18 2249 & B0800 0.61587 0.01042 71271 loc18 2249 & C202 0.69697 0.00857 73700 loc18 2249 & H462 0.00402 0.00110 70438 loc18 6567 & B0800 0.61661 0.01226 76863 loc18 6567 & C202 0.46406 0.01385 77467 loc18 6567 & H462 0.00000 0.00000 76404 loc18 6567 & 2249 0.27444 0.01106 73599 loc18 3409 & B0800 0.89256 0.00397 67354 loc18 3409 & C202 0.35825 0.01072 69985 loc18 3409 & H462 0.00713 0.00132 65958 loc18 3409 & 2249 0.72098 0.00757 75655 loc18 3409 & 6567 0.43770 0.01038 68564 Locus: loc19 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 6 7 8 9 10 11 12 13 Total B0800 0 18 34 13 81 38 26 0 210 C202 0 1 2 8 85 77 29 1 203 H462 0 1 0 3 93 65 46 1 209 2249 1 20 16 13 51 37 20 0 158 6567 0 20 21 10 79 52 26 0 208 3409 0 11 8 4 32 16 9 2 82 Total: 1 71 81 51 421 285 156 4 1070 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc19 C202 & B0800 0.00000 0.00000 71189 loc19 H462 & B0800 0.00000 0.00000 70940 loc19 H462 & C202 0.16444 0.00941 57455 loc19 2249 & B0800 0.23360 0.01230 71672 loc19 2249 & C202 0.00000 0.00000 61782 loc19 2249 & H462 0.00000 0.00000 61286 loc19 6567 & B0800 0.34892 0.01189 84260 loc19 6567 & C202 0.00000 0.00000 70815 loc19 6567 & H462 0.00000 0.00000 70057 loc19 6567 & 2249 0.63195 0.01230 71553 loc19 3409 & B0800 0.23305 0.00936 69826 loc19 3409 & C202 0.00000 0.00000 66884 loc19 3409 & H462 0.00000 0.00000 65261 loc19 3409 & 2249 0.51169 0.01041 60995 loc19 3409 & 6567 0.38640 0.00960 69307 Locus: loc20 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 14 15 Total B0800 2 1 33 48 100 23 3 0 210 C202 0 0 19 45 103 28 6 2 203 H462 0 0 13 46 118 26 4 2 209 2249 2 3 23 33 71 22 3 1 158 6567 5 3 34 45 96 22 3 0 208 3409 1 0 13 19 36 11 2 0 82 Total: 10 7 135 236 524 132 21 5 1070 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc20 C202 & B0800 0.12445 0.00935 57877 loc20 H462 & B0800 0.01399 0.00229 57259 loc20 H462 & C202 0.78278 0.00795 74336 loc20 2249 & B0800 0.79309 0.00721 61110 loc20 2249 & C202 0.18379 0.00847 62058 loc20 2249 & H462 0.02627 0.00346 61220 loc20 6567 & B0800 0.87705 0.00547 70887 loc20 6567 & C202 0.00656 0.00124 64399 loc20 6567 & H462 0.00028 0.00015 63720 loc20 6567 & 2249 0.90139 0.00480 64300 loc20 3409 & B0800 0.97895 0.00152 55345 loc20 3409 & C202 0.44169 0.01192 55244 loc20 3409 & H462 0.08675 0.00511 54256 loc20 3409 & 2249 0.91706 0.00320 55015 loc20 3409 & 6567 0.83364 0.00554 64745 Locus: loc21 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 6 7 8 9 10 11 12 Total B0800 35 9 108 38 7 12 0 209 C202 0 1 164 27 1 10 0 203 H462 2 2 163 5 9 26 2 209 2249 21 8 77 31 10 10 1 158 6567 25 12 113 48 4 6 0 208 3409 16 1 39 10 7 9 0 82 Total: 99 33 664 159 38 73 3 1069 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc21 C202 & B0800 0.00000 0.00000 76008 loc21 H462 & B0800 0.00000 0.00000 70214 loc21 H462 & C202 0.00000 0.00000 57497 loc21 2249 & B0800 0.69290 0.01048 68962 loc21 2249 & C202 0.00000 0.00000 65221 loc21 2249 & H462 0.00000 0.00000 71346 loc21 6567 & B0800 0.29787 0.01223 79247 loc21 6567 & C202 0.00000 0.00000 73997 loc21 6567 & H462 0.00000 0.00000 69916 loc21 6567 & 2249 0.13953 0.00785 68352 loc21 3409 & B0800 0.14263 0.00656 75048 loc21 3409 & C202 0.00000 0.00000 63701 loc21 3409 & H462 0.00000 0.00000 60155 loc21 3409 & 2249 0.24360 0.00864 63418 loc21 3409 & 6567 0.00089 0.00033 74384 Locus: loc22 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 6 7 8 9 10 11 12 13 Total B0800 1 0 46 38 32 82 10 0 209 C202 0 0 57 23 14 93 16 0 203 H462 0 0 69 9 5 88 37 1 209 2249 0 0 25 38 18 67 10 0 158 6567 3 1 46 62 27 58 11 0 208 3409 0 1 14 17 4 38 8 0 82 Total: 4 2 257 187 100 426 92 1 1069 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc22 C202 & B0800 0.00729 0.00220 71987 loc22 H462 & B0800 0.00000 0.00000 63989 loc22 H462 & C202 0.00054 0.00035 70524 loc22 2249 & B0800 0.33760 0.01203 70042 loc22 2249 & C202 0.00219 0.00076 84022 loc22 2249 & H462 0.00000 0.00000 70086 loc22 6567 & B0800 0.05370 0.00566 67825 loc22 6567 & C202 0.00000 0.00000 67215 loc22 6567 & H462 0.00000 0.00000 60629 loc22 6567 & 2249 0.03739 0.00411 65399 loc22 3409 & B0800 0.03262 0.00419 52878 loc22 3409 & C202 0.07869 0.00542 62773 loc22 3409 & H462 0.00000 0.00000 51239 loc22 3409 & 2249 0.30132 0.01014 64585 loc22 3409 & 6567 0.01138 0.00149 64286 Locus: loc23 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 5 6 7 8 9 Total B0800 0 43 125 27 15 210 C202 0 80 47 30 46 203 H462 1 87 88 11 22 209 2249 1 44 76 31 6 158 6567 1 58 104 36 9 208 3409 1 27 35 9 10 82 Total: 4 339 475 144 108 1070 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc23 C202 & B0800 0.00000 0.00000 87853 loc23 H462 & B0800 0.00000 0.00000 70012 loc23 H462 & C202 0.00000 0.00000 70921 loc23 2249 & B0800 0.03305 0.00374 67624 loc23 2249 & C202 0.00000 0.00000 69276 loc23 2249 & H462 0.00004 0.00004 71272 loc23 6567 & B0800 0.07907 0.00630 69412 loc23 6567 & C202 0.00000 0.00000 70623 loc23 6567 & H462 0.00000 0.00000 71816 loc23 6567 & 2249 0.97099 0.00164 70287 loc23 3409 & B0800 0.02503 0.00262 60479 loc23 3409 & C202 0.00624 0.00167 61963 loc23 3409 & H462 0.39882 0.00926 67653 loc23 3409 & 2249 0.06469 0.00402 68686 loc23 3409 & 6567 0.10533 0.00640 67643 Locus: loc24 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 6 7 8 9 10 Total B0800 3 60 51 90 6 210 C202 12 23 22 145 1 203 H462 10 53 23 122 1 209 2249 4 44 41 64 5 158 6567 0 44 70 92 2 208 3409 3 16 25 36 2 82 Total: 32 240 232 549 17 1070 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc24 C202 & B0800 0.00000 0.00000 78102 loc24 H462 & B0800 0.00020 0.00020 77837 loc24 H462 & C202 0.00685 0.00141 70232 loc24 2249 & B0800 0.94390 0.00261 76543 loc24 2249 & C202 0.00000 0.00000 76649 loc24 2249 & H462 0.00017 0.00014 76471 loc24 6567 & B0800 0.02914 0.00260 71931 loc24 6567 & C202 0.00000 0.00000 72684 loc24 6567 & H462 0.00000 0.00000 72536 loc24 6567 & 2249 0.01565 0.00167 72170 loc24 3409 & B0800 0.45073 0.00891 71414 loc24 3409 & C202 0.00003 0.00002 69173 loc24 3409 & H462 0.00153 0.00037 69506 loc24 3409 & 2249 0.66386 0.00735 72841 loc24 3409 & 6567 0.07054 0.00524 64270 Locus: loc25 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 Total B0800 15 72 34 55 27 6 209 C202 7 40 24 72 51 8 202 H462 6 32 56 79 33 2 208 2249 12 61 16 46 17 6 158 6567 14 68 36 66 19 3 206 3409 10 23 14 26 6 3 82 Total: 64 296 180 344 153 28 1065 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc25 C202 & B0800 0.00034 0.00019 82174 loc25 H462 & B0800 0.00000 0.00000 80486 loc25 H462 & C202 0.00083 0.00046 80134 loc25 2249 & B0800 0.59166 0.01194 81326 loc25 2249 & C202 0.00035 0.00025 81295 loc25 2249 & H462 0.00000 0.00000 79505 loc25 6567 & B0800 0.62854 0.01065 81310 loc25 6567 & C202 0.00001 0.00001 81736 loc25 6567 & H462 0.00009 0.00007 78523 loc25 6567 & 2249 0.25863 0.01086 80049 loc25 3409 & B0800 0.47609 0.01148 77468 loc25 3409 & C202 0.00162 0.00048 77448 loc25 3409 & H462 0.00084 0.00037 74184 loc25 3409 & 2249 0.35985 0.00972 76614 loc25 3409 & 6567 0.60606 0.00783 75274 Locus: loc26 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 8 9 10 11 12 13 14 15 Total B0800 0 11 12 68 51 63 4 0 209 C202 1 2 3 38 86 58 13 1 202 H462 1 1 16 52 86 41 10 1 208 2249 0 8 15 49 38 39 8 1 158 6567 0 18 9 63 58 54 4 0 206 3409 0 4 7 21 23 21 6 0 82 Total: 2 44 62 291 342 276 45 3 1065 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc26 C202 & B0800 0.00000 0.00000 62068 loc26 H462 & B0800 0.00000 0.00000 62413 loc26 H462 & C202 0.03907 0.00389 61859 loc26 2249 & B0800 0.33859 0.01282 69267 loc26 2249 & C202 0.00000 0.00000 62596 loc26 2249 & H462 0.00612 0.00131 62929 loc26 6567 & B0800 0.64633 0.01078 79853 loc26 6567 & C202 0.00000 0.00000 62632 loc26 6567 & H462 0.00000 0.00000 63200 loc26 6567 & 2249 0.12728 0.00875 69548 loc26 3409 & B0800 0.28242 0.00926 75774 loc26 3409 & C202 0.01317 0.00225 51882 loc26 3409 & H462 0.13147 0.00734 51940 loc26 3409 & 2249 0.94962 0.00315 64371 loc26 3409 & 6567 0.18691 0.00820 76285 Locus: loc27 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 9 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 33 34 41 Total B0800 1 0 11 28 0 12 41 12 4 43 9 2 2 19 4 0 0 0 1 4 193 C202 0 1 0 88 1 11 2 10 2 62 4 2 0 4 2 0 1 1 0 2 193 H462 0 3 1 90 2 5 5 2 5 54 10 0 2 8 3 7 0 0 1 3 201 2249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Total: 1 4 12 206 3 28 48 24 11 159 23 4 4 31 9 7 1 1 2 9 587 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc27 C202 & B0800 0.00000 0.00000 49982 loc27 H462 & B0800 0.00000 0.00000 57473 loc27 H462 & C202 0.01148 0.00222 49741 loc27 2249 & B0800 No table loc27 2249 & C202 No table loc27 2249 & H462 No table loc27 6567 & B0800 No table loc27 6567 & C202 No table loc27 6567 & H462 No table loc27 6567 & 2249 No table loc27 3409 & B0800 No table loc27 3409 & C202 No table loc27 3409 & H462 No table loc27 3409 & 2249 No table loc27 3409 & 6567 No table Locus: loc28 ================================= Pop Alleles: ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 12 17 18 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 Total B0800 1 1 3 1 11 8 3 34 13 2 4 37 22 4 17 3 1 28 0 0 0 193 C202 0 0 12 3 4 4 1 74 14 4 1 12 28 2 27 0 2 1 0 2 2 193 H462 0 1 14 1 4 2 2 55 21 5 2 16 5 24 43 0 1 1 1 2 1 201 2249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Total: 1 2 29 5 19 14 6 163 48 11 7 65 55 30 87 3 4 30 1 4 3 587 Locus Population pair P-Value S.E. Switches ----------- --------------------- ------- ------- -------- loc28 C202 & B0800 0.00000 0.00000 55976 loc28 H462 & B0800 0.00000 0.00000 54077 loc28 H462 & C202 0.00000 0.00000 55310 loc28 2249 & B0800 No table loc28 2249 & C202 No table loc28 2249 & H462 No table loc28 6567 & B0800 No table loc28 6567 & C202 No table loc28 6567 & H462 No table loc28 6567 & 2249 No table loc28 3409 & B0800 No table loc28 3409 & C202 No table loc28 3409 & H462 No table loc28 3409 & 2249 No table loc28 3409 & 6567 No table ================================= P-value for each population pair across all loci (Fisher's method) ----------------------------------------------------- Population pair Chi2 df P-Value -------------------- -------- --- -------- B0800 & C202 Infinity 56 Highly sign. B0800 & H462 Infinity 56 Highly sign. C202 & H462 Infinity 56 Highly sign. B0800 & 2249 66.15746 52 0.089604 C202 & 2249 Infinity 52 Highly sign. H462 & 2249 Infinity 52 Highly sign. B0800 & 6567 75.608640 52 0.017915 C202 & 6567 Infinity 52 Highly sign. H462 & 6567 Infinity 52 Highly sign. 2249 & 6567 73.468548 52 0.026596 B0800 & 3409 97.345239 52 0.000141 C202 & 3409 Infinity 52 Highly sign. H462 & 3409 Infinity 52 Highly sign. 2249 & 3409 82.532702 52 0.004469 6567 & 3409 Infinity 52 Highly sign. Normal ending. -------------------------------------------------------------------------------- Results from GENEPOP -------------------------------------------------------------------------------- Fri Aug 12 10:51:11 WST 2011 [Profile] Title="African American" NbSamples=6 DataType=STANDARD GenotypicData=1 LocusSeparator=WHITESPACE GameticPhase=0 RecessiveData=0 MissingData="?" [Data] [[Samples]] SampleName="B0600" SampleSize=210 SampleData= { 1 1 15 17 15 16 23 27 12 13 28 30 12 18 13 13 12 12 10 11 08 11 07 08 09 09 09 13 18 24 2 1 14 15 16 16 23 24 14 17 28 29 14 20 07 13 11 12 10 11 10 13 08 11 06 07 11 13 29 29 3 1 15 15 16 17 24 25 11 13 30 31 15 17 11 13 11 11 09 12 08 12 09 11 06 08 09 11 28 34 4 1 16 16 17 18 21 22 11 14 27 28 15 17 11 13 08 15 08 11 10 13 08 09 07 09 13 14 ? ? 5 1 14 14 14 14 20 27 12 15 29 29 14 15 11 12 11 13 10 11 10 11 08 09 09 10 09 10 24 24 6 1 16 16 17 18 21 25 14 14 31 31 15 15 11 12 12 12 10 14 11 12 06 08 07 09 09 13 24 24 7 1 14 17 15 19 23 24 14 15 28 37 15 15 11 12 12 13 11 12 10 13 11 11 07 09 11 12 24 29 8 1 17 17 15 16 22 27 13 14 27 28 12 21 11 12 11 12 08 11 10 12 08 09 06 09 11 13 24 28 9 1 16 17 16 17 22 25 10 13 29 30 13 17 10 11 08 12 11 11 11 12 08 11 06 09 12 12 24 24 10 1 15 15 17 20 21 22 14 15 27 31 16 17 08 12 10 11 10 11 08 11 09 09 08 09 10 11 17 20 11 1 15 16 14 17 22 24 13 16 28 30 17 17 11 13 12 13 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18 12 12 11 12 10 10 ? ? ? ? ? ? ? ? ? ? 222 1 15 16 15 17 24 25 13 16 28 28 15 16 10 12 11 12 09 11 ? ? ? ? ? ? ? ? ? ? 223 1 15 17 15 18 25 25 10 12 27 30 16 17 12 12 11 11 10 10 ? ? ? ? ? ? ? ? ? ? 224 1 17 17 16 17 19 24 12 13 28 29 17 20 13 13 12 12 10 11 ? ? ? ? ? ? ? ? ? ? 225 1 14 15 15 17 22 25 14 14 27 29 15 16 11 11 11 12 10 11 ? ? ? ? ? ? ? ? ? ? 226 1 15 18 16 19 19 23 14 17 27 29 16 19 12 12 12 12 09 09 ? ? ? ? ? ? ? ? ? ? 227 1 15 17 16 16 22 24 13 15 29 30 15 17 09 13 12 12 08 09 ? ? ? ? ? ? ? ? ? ? 228 1 16 17 16 16 22 23 15 16 27 28 14 17 12 13 11 12 11 12 ? ? ? ? ? ? ? ? ? ? 229 1 14 16 15 19 20 25 13 15 30 36 11 16 10 13 11 12 10 11 ? ? ? ? ? ? ? ? ? ? 230 1 15 16 17 17 21 22 14 14 28 28 16 20 13 13 12 12 08 10 ? ? ? ? ? ? ? ? ? ? 231 1 16 16 15 17 22 26 14 14 32 33 18 18 11 13 11 12 09 11 ? ? ? ? ? ? ? ? ? ? 232 1 15 15 16 16 22 24 13 15 27 31 17 18 11 13 11 14 08 10 ? ? ? ? ? ? ? ? ? ? 233 1 16 16 15 16 19 21 14 16 27 31 12 15 11 14 11 12 08 08 ? ? ? ? ? ? ? ? ? ? 234 1 14 16 15 18 24 26 12 15 29 30 16 19 12 13 12 14 10 10 ? ? ? ? ? ? ? ? ? ? 235 1 15 17 15 17 19 23 13 15 28 32 16 19 11 12 12 12 08 12 ? ? ? ? ? ? ? ? ? ? 236 1 16 16 15 18 24 26 13 14 27 31 17 20 12 12 11 12 08 10 ? ? ? ? ? ? ? ? ? ? 237 1 15 16 15 15 20 21 14 15 28 30 11 23 11 12 11 11 08 10 ? ? ? ? ? ? ? ? ? ? 238 1 15 15 15 16 23 25 12 14 29 31 16 18 08 12 12 12 08 09 ? ? ? ? ? ? ? ? ? ? 239 1 14 15 16 17 26 27 13 14 29 29 12 21 11 11 08 12 11 11 ? ? ? ? ? ? ? ? ? ? 240 1 14 15 15 19 21 23 13 14 28 32 19 20 12 13 11 13 10 12 ? ? ? ? ? ? ? ? ? ? 241 1 16 18 15 15 18 27 15 16 27 31 16 18 10 12 11 12 08 10 ? ? ? ? ? ? ? ? ? ? 242 1 15 15 16 18 21 21 10 14 30 30 14 15 12 13 09 14 11 12 ? ? ? ? ? ? ? ? ? ? 243 1 15 18 16 16 19 26 13 14 29 32 15 21 08 12 11 12 08 08 ? ? ? ? ? ? ? ? ? ? 244 1 15 17 16 18 22 25 14 14 27 30 15 17 12 12 11 13 10 12 ? ? ? ? ? ? ? ? ? ? } SampleName="3001" SampleSize=85 SampleData= { 1 1 17 18 14 16 22 24 10 13 29 33 11 13 10 11 08 12 10 12 10 12 09 09 07 09 09 11 ? ? 2 1 16 18 16 18 23 23 14 14 27 28 14 16 12 12 11 13 10 10 12 12 09 12 07 08 08 09 ? ? 3 1 14 17 16 20 23 25 13 15 28 33 16 19 12 12 10 11 10 11 10 10 06 08 07 09 08 11 ? ? 4 1 17 18 17 17 22 24 14 14 28 32 15 16 10 12 11 12 09 10 10 12 06 09 07 09 08 11 ? ? 5 1 15 16 15 20 22 25 11 15 30 30 12 19 11 12 12 12 10 11 09 11 06 09 07 07 12 12 ? ? 6 1 15 18 16 16 19 19 12 13 29 30 14 16 11 11 11 13 10 10 08 12 11 12 07 09 13 13 ? ? 7 1 15 16 15 17 24 27 15 15 31 31 14 16 07 12 10 14 10 11 11 14 09 12 07 07 13 13 ? ? 8 1 14 15 14 15 22 24 13 14 27 30 15 19 09 11 09 13 09 10 07 11 08 09 07 08 12 13 ? ? 9 1 15 16 16 19 21 23 13 16 28 29 14 19 11 12 11 12 09 10 09 12 08 08 08 08 10 12 ? ? 10 1 ? ? 15 16 ? ? ? ? ? ? ? ? 12 13 12 13 10 11 11 12 10 11 07 09 11 11 ? ? 11 1 15 16 16 18 24 25 11 14 27 30 16 20 11 12 12 12 08 08 11 11 06 08 07 08 11 11 ? ? 12 1 15 15 15 16 22 25 12 14 30 31 19 21 11 12 10 14 10 11 11 13 06 09 06 08 11 14 ? ? 13 1 15 18 19 19 19 21 14 14 27 31 15 16 11 11 11 14 08 10 10 11 08 11 06 07 09 13 ? ? 14 1 15 17 17 17 22 22 14 14 28 31 19 20 13 13 08 12 09 11 10 10 08 11 06 09 11 12 ? ? 15 1 16 16 16 16 23 29 13 15 27 28 15 15 11 12 11 13 10 12 12 12 10 11 07 09 09 13 ? ? 16 1 16 17 15 17 23 24 13 14 28 29 15 19 10 11 12 12 10 12 12 12 08 09 07 07 10 11 ? ? 17 1 15 18 13 16 22 24 14 15 28 28 13 16 11 11 12 13 10 11 08 12 11 11 06 09 09 12 ? ? 18 1 15 17 15 16 23 25 12 13 29 35 20 20 11 14 12 13 11 11 10 12 08 10 06 08 10 12 ? ? 19 1 15 16 15 16 20 20 14 15 29 31 16 18 11 12 11 13 10 11 10 11 08 09 09 09 11 13 ? ? 20 1 16 18 17 18 19 23 13 13 31 32 16 16 08 11 11 11 08 12 08 13 07 08 06 09 11 12 ? ? 21 1 14 15 15 15 22 23 11 12 29 29 13 20 10 10 08 08 10 10 10 11 11 12 06 08 10 11 ? ? 22 1 15 16 16 17 22 26 13 14 28 31 16 20 12 13 12 13 10 11 13 13 09 09 07 08 08 11 ? ? 23 1 15 17 16 19 23 24 13 14 28 30 13 17 11 12 12 14 08 11 12 12 08 09 07 07 08 12 ? ? 24 1 17 18 11 18 20 22 11 13 29 30 15 18 10 12 08 11 10 11 10 10 11 11 06 07 11 13 ? ? 25 1 14 15 17 18 19 24 12 12 28 30 16 18 10 12 12 14 08 08 07 10 09 11 07 08 11 13 ? ? 26 1 15 17 15 19 21 22 11 15 28 29 16 20 12 14 12 13 08 10 07 10 06 08 09 10 08 10 ? ? 27 1 15 17 14 16 20 23 14 14 29 32 17 19 12 12 09 14 08 10 10 11 08 11 06 07 09 11 ? ? 28 1 16 17 14 18 19 23 14 15 27 31 13 20 08 11 13 13 10 12 08 08 08 10 06 07 08 12 ? ? 29 1 17 18 16 17 20 23 15 15 30 32 16 17 11 13 13 13 10 11 11 11 08 09 06 08 11 12 ? ? 30 1 15 18 15 16 21 24 13 14 30 30 15 19 11 12 12 12 09 11 10 11 08 08 07 08 08 10 ? ? 31 1 16 16 15 18 24 24 12 14 31 33 14 15 08 13 11 12 10 11 11 11 08 11 07 08 11 13 ? ? 32 1 15 16 17 18 21 25 13 14 28 29 13 14 12 12 11 14 08 10 10 12 09 12 07 09 09 13 ? ? 33 1 15 17 17 18 20 24 12 14 27 35 11 21 11 12 11 11 08 10 11 11 08 09 07 09 11 13 ? ? 34 1 15 18 16 16 24 24 12 15 27 28 17 20 10 14 13 14 10 10 08 11 06 08 08 10 09 10 ? ? 35 1 16 16 16 19 19 27 15 16 29 34 18 18 11 13 11 12 08 10 10 12 06 07 07 08 11 11 ? ? 36 1 15 17 15 17 21 25 13 13 30 33 13 13 11 13 10 14 10 13 10 13 08 08 06 08 09 12 ? ? 37 1 16 17 14 16 21 27 08 14 29 30 12 14 08 12 11 11 09 10 07 10 08 08 07 07 09 10 ? ? 38 1 16 18 17 18 24 25 12 16 28 28 14 16 10 12 11 14 08 10 07 10 06 11 07 09 10 10 ? ? 39 1 15 16 15 16 22 24 14 14 28 29 16 18 12 13 11 12 11 12 10 12 09 11 06 09 09 11 ? ? 40 1 15 16 16 17 22 30 10 14 28 30 16 19 10 13 11 14 08 09 11 11 08 11 09 09 10 13 ? ? 41 1 15 16 16 16 21 22 10 14 28 29 12 17 11 12 11 11 11 13 08 12 06 08 07 09 11 12 ? ? 42 1 15 16 15 16 24 24 10 15 30 30 13 16 11 14 12 14 08 10 10 12 10 11 06 08 11 12 ? ? 43 1 16 17 16 17 25 26 15 16 28 32 14 14 07 10 11 14 08 12 10 12 10 11 07 08 09 11 ? ? 44 1 15 15 15 16 21 24 13 16 29 31 15 15 11 11 11 12 11 11 07 11 08 11 07 08 08 09 ? ? 45 1 17 18 16 17 24 31 13 14 28 29 13 18 11 12 13 13 10 10 10 10 08 10 06 08 10 12 ? ? 46 1 15 17 16 16 20 25 13 15 29 34 12 16 12 12 11 11 09 11 09 12 08 09 07 08 11 11 ? ? 47 1 15 17 16 17 22 24 11 15 30 31 16 16 12 13 11 11 10 11 07 11 06 09 07 07 12 14 ? ? 48 1 16 16 16 17 22 23 12 13 28 30 12 19 12 13 12 12 09 12 10 10 06 11 08 08 13 13 ? ? 49 1 14 16 15 16 24 28 10 13 29 30 21 21 11 13 11 12 08 08 10 12 08 09 07 09 09 09 ? ? 50 1 ? ? 15 17 ? ? ? ? ? ? ? ? 09 13 12 13 08 11 10 13 06 11 09 09 09 10 ? ? 51 1 15 16 16 17 21 23 11 13 28 29 16 17 10 13 11 12 11 12 12 13 08 08 07 07 10 13 ? ? 52 1 14 15 15 17 23 26 13 15 30 31 12 15 12 13 11 12 11 12 07 13 06 09 07 07 09 11 ? ? 53 1 15 15 16 17 22 23 13 16 28 29 12 15 12 13 13 13 09 10 11 11 06 08 08 08 09 11 ? ? 54 1 15 15 18 18 20 28 11 14 28 32 13 20 12 12 12 12 10 11 10 12 11 12 08 09 09 10 ? ? 55 1 16 16 14 17 20 23 10 13 27 32 12 16 10 12 09 13 09 09 11 12 11 11 07 07 11 11 ? ? 56 1 16 17 14 17 24 24 12 15 28 31 12 15 10 11 12 12 08 08 10 12 08 11 09 09 11 12 ? ? 57 1 15 18 17 18 18 20 10 12 30 31 14 15 10 11 12 13 10 11 11 12 10 11 09 09 09 11 ? ? 58 1 16 17 14 14 22 25 10 15 31 33 13 14 10 12 08 12 12 12 10 12 09 11 09 09 11 14 ? ? 59 1 ? ? 16 18 ? ? ? ? ? ? ? ? 09 12 ? ? ? ? ? ? ? ? ? ? ? ? ? ? 60 1 15 16 17 18 23 24 12 15 30 32 13 14 11 13 08 09 09 10 11 13 08 11 06 09 11 11 ? ? 61 1 15 17 17 17 22 24 13 14 29 30 16 21 11 13 11 11 10 11 12 13 08 11 06 06 09 12 ? ? 62 1 16 18 18 18 23 25 12 12 29 31 15 17 10 11 11 12 08 12 13 13 08 11 08 08 11 11 ? ? 63 1 16 17 18 19 25 25 12 13 30 32 13 15 10 12 10 11 10 12 12 12 08 11 06 06 10 14 ? ? 64 1 15 17 14 17 19 20 12 16 28 30 16 16 09 11 09 10 08 08 10 10 08 11 08 09 11 13 ? ? 65 1 15 17 17 17 22 22 12 12 32 32 14 16 11 13 12 14 10 10 12 12 09 11 06 09 10 14 ? ? 66 1 17 18 14 17 20 20 15 16 29 29 12 14 10 11 08 11 10 11 11 12 08 11 06 09 12 13 ? ? 67 1 15 16 16 17 25 26 12 15 28 28 11 15 10 12 11 12 08 12 10 12 08 08 06 09 12 13 ? ? 68 1 16 17 16 16 21 23 13 15 29 29 14 15 10 10 11 12 09 11 10 10 08 11 08 09 09 12 ? ? 69 1 ? ? 17 18 ? ? ? ? ? ? ? ? 11 11 11 12 08 08 10 12 11 11 07 09 09 12 ? ? 70 1 16 16 15 17 21 22 12 14 28 32 12 12 09 13 10 11 08 11 11 12 08 11 06 08 10 13 ? ? 71 1 16 17 17 18 22 25 13 15 28 32 13 16 11 11 08 11 10 11 11 12 08 11 06 09 08 11 ? ? 72 1 16 17 14 18 20 24 14 15 29 30 11 14 12 12 12 13 09 10 10 10 08 08 09 09 11 12 ? ? 73 1 14 15 16 17 21 26 11 16 28 33 12 13 11 11 12 12 07 11 10 11 10 12 09 09 11 12 ? ? 74 1 ? ? 14 17 ? ? ? ? ? ? ? ? 10 12 10 12 08 13 10 12 08 11 09 09 09 09 ? ? 75 1 15 18 16 17 19 25 11 13 31 33 15 16 10 11 11 13 08 08 12 12 06 11 08 09 11 13 ? ? 76 1 16 18 15 19 23 26 14 15 27 33 ? ? 12 13 12 12 09 11 08 12 08 09 06 06 12 12 ? ? 77 1 14 15 14 18 24 24 13 15 30 31 15 16 11 12 11 11 08 09 07 10 08 09 07 09 10 12 ? ? 78 1 16 16 16 16 22 23 12 14 32 34 ? ? 11 11 13 13 10 10 09 12 11 11 05 07 09 12 ? ? 79 1 15 15 16 17 22 24 13 13 28 30 16 19 12 12 12 13 11 12 11 14 08 11 06 07 10 13 ? ? 80 1 16 16 17 18 22 26 14 14 28 29 13 15 12 12 09 10 08 12 07 11 08 11 06 07 09 11 ? ? 81 1 16 17 15 17 21 21 12 13 29 32 19 21 10 16 09 12 08 10 10 13 10 11 06 09 11 14 ? ? 82 1 16 17 16 17 18 24 11 13 29 33 17 20 10 13 11 12 09 11 07 11 11 12 07 08 10 13 ? ? 83 1 16 17 14 20 23 23 14 14 28 32 16 18 12 12 11 12 10 11 08 12 09 10 07 08 11 12 ? ? 84 1 15 16 15 17 21 23 11 13 29 30 15 19 11 12 12 12 10 10 ? ? ? ? ? ? ? ? ? ? 85 1 14 16 16 16 20 24 12 14 31 31 15 18 11 12 09 12 08 09 ? ? ? ? ? ? ? ? ? ? } References Raymond M. &Rousset F, 1995. GENEPOP (version 1.2):population genetics software for exact tests and ecumenicism.J. Heredity, 86:248-249 Crow, Jf (Jul 1999). "Hardy, Weinberg and language impediments." (Free full text). Genetics 152 (3): 821–5. ISSN 0016-6731. PMC 1460671. PMID 10388804. http://www.genetics.org/cgi/pmidlookup?view=long&pmid=10388804. Edwards, A.W.F. 1977. Foundations of Mathematical Genetics. Cambridge University Press, Cambridge (2nd ed., 2000). ISBN 0-521-77544-2 Read More