quora
Nobody downloaded yet

The Effect of Sildenafil on mouse oocyte development in vivo followed by in vitro culture until the blastocyst stage - Literature review Example

Comments (0) Cite this document
Summary
Although there has been remarkable progress in the field of assisted reproduction technology (ART) since 1978, pregnancy rates have not yet reached the expected levels. Two of the most common problems in ART are poor ovarian response and implantation failure after ovarian…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER97% of users find it useful
The Effect of Sildenafil on mouse oocyte development in vivo followed by in vitro culture until the blastocyst stage
Read TextPreview

Extract of sample
"The Effect of Sildenafil on mouse oocyte development in vivo followed by in vitro culture until the blastocyst stage"

Download file to see previous pages ersity, Belfast, Glenn took samples of sperm from volunteers and bathed them in weak solutions of sildenafil citrate, to produce a dosage, equal to that found in the blood of a male who had consumed a tablet of the drug. The behaviour of the treated sperm was compared with another sample of untreated sperm. The findings indicate that sildenafil citrate increased the activity level of the sperms, but found that it damaged the acrosome of the sperm, which contains enzymes needed to dissolve the membrane of a womans oocyte. This meant that the acrosome breaks down early, and thus, it is not able to act on the womans eggs, and fertilisation does not take place (McKie, 2008).
Sildenafil has been used with great success for the treatment of erectile problems in males since 1997 (Sher et al. 2000). The fact that NO synthase is present in the ovarian cells, the endometrium (Hattori and Tabata, 2006) and within the ovarian vascular network (Sher, et al. 2000) combined with the finding that its vasodilatory effects show a positive correlation to its concentration, oriented the researchers (Tamanini, et al., 2002) to use sildenafil as a treatment for hypertension and Intrauterine Growth Restriction (IUGR) during pregnancy (Sasser and Baylis, 2010).
A research by Neithardt et al. (2005) studied the process of embryo after loading, by placing the catheter and a dose of sildenafil citrate, applied vaginally for 127 women who had difficulty in conceiving. After some time, the researchers found that the pregnancy rate of women with ET, was 52.4%, and at the same time, it was 34.9% for the group who were not administered the dose. The researchers therefore concluded that sildenafil citrate impacts the success of embryo transplant after loading. In a related research, Zinger et al. (2006) used sildenafil citrate to treat two infertile women, who suffered from the Ashermans syndrome. The women had a thin endometrium, and had subsequently failed to conceive in previous IVF ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“The Effect of Sildenafil on mouse oocyte development in vivo followed Literature review”, n.d.)
The Effect of Sildenafil on mouse oocyte development in vivo followed Literature review. Retrieved from https://studentshare.org/biology/1653794-the-effect-of-sildenafil-on-mouse-oocyte-development-in-vivo-followed-by-in-vitro-culture-until-the-blastocyst-stage
(The Effect of Sildenafil on Mouse Oocyte Development in Vivo Followed Literature Review)
The Effect of Sildenafil on Mouse Oocyte Development in Vivo Followed Literature Review. https://studentshare.org/biology/1653794-the-effect-of-sildenafil-on-mouse-oocyte-development-in-vivo-followed-by-in-vitro-culture-until-the-blastocyst-stage.
“The Effect of Sildenafil on Mouse Oocyte Development in Vivo Followed Literature Review”, n.d. https://studentshare.org/biology/1653794-the-effect-of-sildenafil-on-mouse-oocyte-development-in-vivo-followed-by-in-vitro-culture-until-the-blastocyst-stage.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
CHECK THESE SAMPLES - THEY ALSO FIT YOUR TOPIC
The In-Vivo and In-Vitro Effects of Sildenafil (Viagra) on Oocyte and Embryo Development
Table of Contents 1. Introduction …………………………………………………………………………. 3 1.1 Infertility Problems in Women ……………………………………………. 3 1.2 General Overview of Physiology and Anatomy of Female Reproduction .
31 Pages(7750 words)Literature review
Impact of National Culture on Organisational Culture
According to Hofstede (1983), effective organisations operating in multiple countries have adapted management ideas of their own to local cultures. Hofstede (1993) has also highlighted that the different management theories have cultural constraints meaning that these theories have no value once they enter the border of different country with different culture.
5 Pages(1250 words)Literature review
The Effect of Sildenafil on Embryo Development
This essay analyzes that to solve problems related to fertility problems, ART was developed as a promising solution. The in Vitro fertilization is a good example of ART. To increase the success rate of IVF, the clinical and laboratory procedures were enhanced in order to reduce the risk of side-effects on the part of the patients.
4 Pages(1000 words)Literature review
Cross culture literature review
The main characteristics of a leader are the functions of situation and time and tend to be different across different countries and cultures. Therefore the managers of different international organizations should obtain knowledge about such cultural characteristics and differences to execute leadership and decision making tasks with the utmost efficiency and versatility (Bass, 2000, pp.
6 Pages(1500 words)Literature review
The effect of NO/cGMP system on sheep somatic cell differentiation in vitro
For this reason, a healthy ovarial follicle development is essential part of a successful pregnancy. The actual formation of the follicle antrum can trigger some rearrangement in the blood vessel network (Zimmermann et al., 2003). In line with this, Kaczmarek et al.
4 Pages(1000 words)Literature review
In Vivo And In Vitro Experimental Research
In biological term, in vivo translates to the issue where it occurs. Subject are examined in their natural environment. For instance, the observation of dolphins at sea. This is their natural environment and in contrast to in vitro, they are not moved to an aquarium that for experimental purposes are more convenient.
4 Pages(1000 words)Essay
My Psychosocial Stage of Development
The theory also offers an explanation for the issues and challenges faced by individuals, and links them to issues faced in the successful resolution of a previous conflict (Kail & Cavanaugh, 2004). This theory can be used to understand the behavior and thoughts of others as well as oneself.
3 Pages(750 words)Essay
Heamatology ( The effect of the environmental pollution in the development of Acute lymphoblastic leukaemia
Other environmental risk factors include non-ionizing radiations, hydrocarbons, and pesticides. Belson et al explained that childhood lymphoblastic leukaemia is a rare occurrence and this makes
4 Pages(1000 words)Literature review
The invitro effect of sildenafil citrate on the outcome of pregnancy in mice and offsprings
It is necessary to establish a normal uterine blood flow so as to ensure the development of a successful embryo. Around the world, many couples experience difficulty conceiving a child. As a result of the continual expansion of the assisted reproductive technologies (ART), people have learned to accept the practice of intracytoplasmic sperm injection (ICSI), gestational surrogacy, the zygote intrafallopian transfer, the gamete intrafallopian transfer (GIFT), oocyte, and embryo donation, gestational surrogacy, and cryopreservation (Zegers-Hochschild et al., 2009).
5 Pages(1250 words)Literature review
The effect of Sildenafil (viagra) on antral follicle development in sheep
In sheep, folliculogenesis is the key process in reproduction and involves the development of ovarian follicles from a small pre-antral follicle into pre-antral then into antral and finally the large pre-ovulatory follicle followed by the corpus luteum formation after ovulation.
4 Pages(1000 words)Literature review
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Literature review on topic The Effect of Sildenafil on mouse oocyte development in vivo followed by in vitro culture until the blastocyst stage for FREE!
logo footer
Contact us:
+16312120006
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us