quora
Nobody downloaded yet

The effect of dystrophin on neuron development in the Central Nervous System - Essay Example

Comments (0) Cite this document
Summary
Name Institution Date The effect of dystrophin on neuron development in the Central Nervous System Dystrophin is a cytoplamic protein and an important part of protein complex, which serves to connect the muscle fiber cytoskeleton to the extracellular matrix surrounding the muscle fiber through a cell membrane Hart 14)…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER91.1% of users find it useful
The effect of dystrophin on neuron development in the Central Nervous System
Read TextPreview

Extract of sample
"The effect of dystrophin on neuron development in the Central Nervous System"

Download file to see previous pages The DMD is the human gene responsible for providing instructions for making dystrophin. Dystrophin is located in muscles such as cardiac muscles (heart) and skeletal muscles (movement). Small amounts of this hormone are present in the brain specifically in the nerve cells. In cardiac and skeletal muscles, this protein hormone is part of a protein complex which work together to protect and strengthen muscle fibers from injury during contraction and relaxation of the muscles (Hart 23). Dystrophin complex often act as an anchor for connecting each framework of the cells of the muscle with protein lattice and other extracellular matrix. Dystrophin may also play an important role in cell signaling through interacting with proteins which receive and send chemical signals. Little is known so far concerning the functions of dystrophin complex in nerve cells (Hart 24). Some studies have suggested that it plays an important role in the normal functioning of synapses and structure, which are specialized connections existing between nerve cells where the occurrence of cell-cell occurs. In this paper, the focus of ascertaining the effect of dystrophin on neuron development in the Central Nervous System According to Shan and Lihsia (13) dystrophin protein plays an integral role in maintaining muscle membrane integrity. Shan and Lihsia showed that accompanying neuropsychiatric disorder and cognitive impairment often presented in most of the DMD proteins suggests that dystrophin plays an integral role in membrane-cytoskeleton function. The study involved growing c.elegans strains on the nematode growth medium plate at 21 degrees Celsius. Transgenic animals were then generated basing mello et al (1991) standard procedure. In order to generate Punc-119::dys-1 (pLC587), the researchers pieced together the 9.0-kb dys-1 genomic sequence obtained from WRM0611bE10 at an exon 30 with the untranslasted region of cDNA and 169-bp dys-1 3 and 3.9-kb dys-1 cDNA, and subcloned was joined into the pBluescript II KS vector existing between NotI and XmaI. The researchers then crossed evIs78 (Punc-129::gfp and oxIs12 (unc-47::gfp integrated transgenes into the available respective strains with a view to visulize cholinergic neurons, and GABA. Synchronized the young adult animals of such strains and the synchronized dys-1 larvae for different stages were all mounted on the 2percent agarose pads and then scored for neuronal displacement with a 40? 1.3 NA Neofluar. This was done with an aim of using the microscope with the captured image, which was captured in a camera, along with the imaging software. Shan and Lihsia findings showed that DYS-1/dystrophin helps in regulating locomotion and muscle integrity. The findings of this study, also show that SAX-7 and STN-2/Y-syntrophin functions to maintain the neural integrity in c.elegans. In yet another study Hart Lidov, Timothy Byers, Simon Watkins, and Louis Kunkel (7) scientific study, this researchers came up with antibody (anti 6-10), which was somewhat more sensitive that the immunolabel dystrophin which were previously available. The researhers then used this anti 6-10 antibody in to investgate whether the asoociation between systrophin and the nervous system. The findings of this study revealed that in the mouse, dystrophin is more abundant in the neurons of the cerebral cortices and the cerebral. This study also revealed that ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“The effect of dystrophin on neuron development in the Central Nervous Essay”, n.d.)
Retrieved from https://studentshare.org/biology/1496882-the-effect-of-dystrophin-on-neuron-development-in
(The Effect of Dystrophin on Neuron Development in the Central Nervous Essay)
https://studentshare.org/biology/1496882-the-effect-of-dystrophin-on-neuron-development-in.
“The Effect of Dystrophin on Neuron Development in the Central Nervous Essay”, n.d. https://studentshare.org/biology/1496882-the-effect-of-dystrophin-on-neuron-development-in.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
CHECK THESE SAMPLES - THEY ALSO FIT YOUR TOPIC
Describe how neurons in the central nervous system communicate. Using examples, discuss how this has helped us to understand hum
They all have the same body structure, but tend to vary in shape and sizes, due to the length of their axon, and the task they handle. Neurons within the nervous system come in three forms; the afferent, efferent, and interneurons. The nervous system is split into the central and peripheral nervous system.
4 Pages(1000 words)Essay
Central Nervous System Depressent Drugs
The drugs are potent and can have adverse affects to different systems, including the cardiac system, thus leading to death when improperly used. Heath Ledger’s death is an example of the abuse of CNS depressants as his heart stopped when the drugs were misused.
3 Pages(750 words)Essay
The Autonomic Nervous System
Therefore, the autonomic nervous system controls the involuntary activities of the smooth muscles and several undertakings o the glands. It forms a component of the peripheral nervous system and can be subdivided into two categories. These include the sympathetic and parasympathetic nervous system. In all these categories are comprised of effector neurons which connect the central nervous system top their effector organs.
7 Pages(1750 words)Essay
Nervous system
353). The cuticle is 5µm thick in young larvae (36 hours, first instar), 25µm in 60-hour-old larvae (second instar), and 40µm in last (third) instar larvae. Maggot behavior is linked to instar development; for example, in the first and second instar the maggots stay close together and feed, but in the third instar, they move away from each other and seek a safe placement for pupal development to occur.
3 Pages(750 words)Essay
Role of Cytokine Signaling during Nervous System Development
Cytokines are liberated by various cells and are utilized extensively in the intercellular communications to bring out diverse activities, admitting complex processes involved in the ontogenetic growth of the brain. This article basically is a review that illustrates the factors that are engaged in the regulation of brain growth as well as discusses the current findings searching the signaling pathways of cytokines during the progression of central nervous system.
3 Pages(750 words)Essay
Central Nervous System
In the Rinne test, with regards to Sensorineural hearing loss, one can expect to find the air condition and bone equally reduced. Also, the results that a person can expect to find with this test are normal. Finally, with regards to conductive hearing loss and the Rinne
1 Pages(250 words)Lab Report
Autonomic Nervous System
The nervous system exists in our body to regulate the involuntary actions like heart beat and breathing by transmitting motor impulses to the organs responsible for carrying out those
1 Pages(250 words)Essay
This week you learned about the central nervous system, i.e., brain structure and neurotransmitters
Major depression episodes entail persistent and extreme levels of depression and stress. Glutamate also has the capacity to
2 Pages(500 words)Essay
Human Nervous System
As the author of the essay puts it, the Central Nervous System form the major portion of the nervous system and includes both the brain as well as the spinal cord. Furthermore, some classifications of the Central Nervous System also include retina and the cranial nerves as part of the Central Nervous System.
5 Pages(1250 words)Essay
Brief introductory description of physiology of the central nervous system related to Parkinson's disease
This research paper will primarily look at what happens when an individual is diagnosed with Parkinson’s disease, the symptoms and its effect on the central nervous system. Parkinson’s
2 Pages(500 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Essay on topic The effect of dystrophin on neuron development in the Central Nervous System for FREE!
logo footer
Contact us:
+16312120006
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us