CHECK THESE SAMPLES OF Main Types of End Point Used in Toxicity Testing in Cellular System
Auditory brain stem response is produced in the Central nervous system after 60 minutes of administration of the drug.... Lidocaine is a hydrological molecule, so it easily crosses the cellular membrane and reaches the blood-brain barrier region.... Lidocaine was used as a tinnitus suppressing drug....
9 Pages
(2250 words)
Essay
Stem cell technology An adult vertebrate is estimated to compose of more than two hundred different types of cells (Marshak et al.... Stem cell research continues to fuel the expectation that an array of promising novel cellular therapeutics will be developed.... It is noteworthy that most of the definitions of stem cells include a notion of self-renewal, coupled with a potential to generate one or more differentiated descendant cell types (Lumelsky in Arlene and Mahendra 162)....
8 Pages
(2000 words)
Research Paper
Drugs are an important component in the treatment of diseases and conditions and this has led to the search for more effective drugs and the means to enhance the efficacy of the drug, while reducing the impact of side effects.... A drug that is developed may have the essential.... ... ... tural configuration and physicochemical properties for providing a desired therapeutic effect, but it is not necessary that it possess the optimal molecular framework and properties to ensure delivery at the targeted site of action....
12 Pages
(3000 words)
Essay
What production system is used depends on the type of protein being developed but can range from mammalian cells, yeast, insect cells or bacteria (Sekhon, 2010).... There is production of a carrier system followed by inoculation of the target with the virus.... A variety of different assays is used for this process (Locatelli and Roger, 2006)....
4 Pages
(1000 words)
Research Paper
The most commonly used chemotherapeutic agents that are used are cyclophosphamide, fluorouracil, platinumbased compounds, anthracycline, and hydroxycamptothecin with quite harmful side effects.... In cancer patients there is a specific group of cells that shows an unusual growth or invasion or the state of metastasis....
11 Pages
(2750 words)
Research Paper
Staining imparts a color to the micro-organisms' by the reaction of the dye with certain structures of the microorganism (Tortora, 2006, p69)A simple stain is alcohol or aqueous based solution of a singular basic dye and its main purpose is to highlight an entire micro-organism in order for its cellular shapes and basic structure to be observed under a microscope (Tortora, 2006, p69).... The author explains why testing the antibiotic susceptibility and resistance of microbes are crucial for the development of drugs to stop infection....
18 Pages
(4500 words)
Term Paper
The paper "The Function of the CYP2A5 and CYP2A6 Genes in Response to Toxic Insults" states that random BR oxidation by ROS deals with the protection of cellular structures against the particular oxidative stress as the enzymatic BR oxidation defends the cells against extra intracellular BR.... Moreover, recently there were findings showing CYP2A5 and CYP2A6 as catalysts contained in bilirubin oxidation and plays a part in harm homeostasis and also in the regulation of cellular redox balance....
8 Pages
(2000 words)
Case Study
he biomarker is a cellular, body fluid, muscle, physiological or biochemical alteration within the extant persons that is utilized quantitatively during biomonitoring for implications of the presence of a significant pollutant as well as an early system warning of imminent effects.... According to the findings of the paper "Biomonitoring for Implications of the Presence of a Significant Pollutant", it can be said that the IC50 is at 50% inhibition of the underlying biological variations of interest within the toxicity test and LOEC of copper sulfate is at 10%....
8 Pages
(2000 words)
Assignment