Nobody downloaded yet

Ugi reaction - Thesis Example

Comments (0) Cite this document
Running head: UGI REACTION Ugi Reaction [Author’s Name] [Class] 15 July 2011 Abstract The Ugi reaction is a four-component chemical reaction that has recently gained unprecedented popularity. This paper defines the Ugi reaction and discusses its advantages…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER98.3% of users find it useful
Ugi reaction
Read TextPreview

Extract of sample "Ugi reaction"

Download file to see previous pages Ugi Reaction The Ugi reaction subject has gained unprecedented prominent in recent chemical literature. An explosion of interest toward the Ugi reaction is explained by the rapid development of chemical technologies and the need to solve organic chemistry challenges in a cost-efficient manner. The history of the Ugi reaction dates back to the middle of the 20th century, but it was not before the beginning of the 21st century that its value and benefits for the evolution of organic chemistry were consistently recognized. Ivar Ugi is believed to be the father of all multicomponent reactions [28]. Ugi is also considered the grandfather of the whole combinatorial chemistry [29]. Today’s chemists rely on the advantages of the Ugi reaction, to synthesize diverse collections/ libraries of biologically interesting products. This is particularly the case of the drug industry, which relies on the premise of discovery and innovations and demands fast methods of chemical analysis and synthesis of complex molecules. The Ugi reaction is a popular object of contemporary chemical research. Dozens of studies were performed to understand the hidden benefits of the Ugi reaction and its implications for chemistry. “The Ugi reaction is the one-pot condensation of an amine, aldehyde or ketone, isocyanide, and a nucleophile to afford ?-substitute carboxamide derivatives” [17]. ...
The carboxylic acid is then added together with the imino carbon; acyl transfer rearranges the resulting acylated isoamide, leading to the creation of the desired product [17]. The benefits of the Ugi reaction are numerous. The Ugi reaction is believed to be the most convenient instrument for generating diverse libraries of chemical compounds [8; 9]. That the reaction occurs at room temperature also means that the reaction is relatively simply and cost-effective: it does not require using artificial additions and can be easily held without complex temperature-regulating mechanisms [9]. The Ugi reaction is extremely advantageous for generating pharmacologically active compounds and diverse molecules [9]. For example, it was extensively used to synthesize anti-malarial agents [9]. Most, if not all, Ugi reaction products tend to precipitate in pure form [9; 15; 21]. This is extremely important for the success of other chemical processes, as long as compound mixtures obtained during the Ugi reaction do not require costly purification prior to being used in other chemical procedures [6; 27]. For example, the Ugi reaction does not require the use of costly chromatography and, consequentially, reduces the costs of the process and the final product. Eventually, almost all compounds obtained during the Ugi reaction are quantifiable [6; 38]. No information about potential drawbacks of the Ugi reaction has been available so far. The current state of literature provides extensive information about the Ugi reaction and its practical applications. This is mostly because the Ugi reaction is gradually turning into the key element of chemical research and analysis, especially in the pharmaceutical industry. More and more chemical compounds are ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Ugi reaction Thesis Example | Topics and Well Written Essays - 1500 words”, n.d.)
Retrieved from
(Ugi Reaction Thesis Example | Topics and Well Written Essays - 1500 Words)
“Ugi Reaction Thesis Example | Topics and Well Written Essays - 1500 Words”, n.d.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document



...?Reaction Paper on David Cole Interviews Dr. Franciszek Piper David Cole Interviews about Auschwitz and its gas chambers are quite informative. According to my perception, the gas chambers have holes that are indicative of the fact that these holes were employed for discharging the gas Zyklon B from outside. Ceilings of the gas chambers were used for discharging the gas inside the chambers. After World War II, changes were made, as the gas chambers are not in its original form. They are reconstructed. They are not fully representing the extremity of their homicide capability, The doors at the time of killing were made airtight while after World War II, there were new doors placed, which were not airtight. In my opinion, the number...
1 Pages(250 words)Essay

Reaction paper

...? The speech given by Benjamin Freedman talks about what really happened during World War I and World War II and how Jews lied to get nations into the massive wars not only once but twice. He says that both of these tragic wars happened because of the Zionists and how their propaganda to keep their businesses thriving led to killings. It was meant to be an eye-opener for those in the audience as he said that no one believed him the first time that he argued his point in front of people. It was also meant to be a warning to prevent a third World War. Such being his objective, then he has so far succeeded. That he was a former Jew and an insider makes what he is saying believable. There is no doubt that there are things about... The speech...
1 Pages(250 words)Essay

Reaction paper

... Judea Declares War on Germany and Freedman’s Speech It is ironic to learn that certain circumstances in history had happened because people allowed them to. It is very sad to realize that the Holocaust was not mainly an evil act by the Germans; rather, it started as an act of defense against nations that collaborated against it. These are the ideas I have formed after reading two intriguing articles –Judea’s declaration of war against Germany and Freedman’s speech. Thanks to the information superhighway, students like me can access such documents that have historical significance. Upon reading Judea’s move against Germany, I find it strange because what has been impressed upon me is that Germany was always on the offensive side... Judea...
2 Pages(500 words)Essay

Business Law/Contract phases

...Details of the contract The contract that is to be discussed in this paper is a joint venture agreement that has been entered by two companies, one being an Indian Infrastructure company by name M/s. CORAMANDEL INFRASTRUCTURE PVT. LTD., (CIPL), a Private Limited Company, incorporated under the Companies Act, 1957 and having its Registered office at #101, Plot No. 120, 1st Floor, GK Classics, Srinagar Colony, Hyderabad -500073, Andhra Pradesh, India and the second company being M/s. UNITED GROUP INFRASTRUCTURE PTY LTD, (UGI), a Private Limited Company, Incorporated laws of Malaysia. The agreement was entered together by both the companies for the purpose of the preparation and submission of a tender (hereinafter called...
6 Pages(1500 words)Essay

Holocaust: Another Horror Story

... Holocaust: Another Horror Story? The main objective of the paper is to present a view regarding the recorded interview ofone of the known personalities exploring the issues related to the holocaust. David Cole was born a Jew and with that information stated there is that biased air which surrounded the start of the documentary interview. Slowly Cole set up the plot of how the film will go. There are quite a few points about the Holocaust itself which were questioned. It was a little shocking that though Cole was a Jew, now an atheist, he remained to side on finding the truth and not what has been published and “revealed” by researches. There are irregularities with the reports that are being disseminated to the public... Holocaust: Another ...
1 Pages(250 words)Essay


...Movie Reaction Movie Reaction: Training The training of employees in an organization is an integral part of development and improvement. In fact, the challenge of improvement and service delivery is based on increased training. The training of the employees is a vital aspect in the management of human resource. Therefore, it is vital for the Human resource team to understand and prepare schedules for training. In the video, several issues are addressed that affect human resource training and improvement (Lambert, 2014). These issues include language training especially when focusing on international market. The training video covers array of issues including effective communication. Effective communication is an important factor... ,...
2 Pages(500 words)Movie Review


...487 words Reaction on The Stamp Act Crisis It’s hard not to notice how controversially The Stamp Act is perceived by representatives of the Crown and by American colonial opposition. To my mind, the key point of the present crisis comes from a different opinion on what policy the kingdom of Great-Britain should provide to not suppress American Colonies’ constitutional Rights and Liberties as of subjects of the Empire while acting in the best interests of the Empire. If looking from a recent historical point of view, concerns of American colonial opposition seem to be fair. It’s almost obvious, that situation has changed greatly after the French and Indian war. The Empire needs to fulfill its resources and looking for...
2 Pages(500 words)Essay


...Reaction al affiliation) Thoughts of Medical School as seen through the experience of Dr. Audrey Young Dr. Audrey Young was 23 years of age when she came forward to illustrate the tales of Medicine school and what the lessons taught prepare them for the various industrial placements. Basing on the fact that the medical school was located in Washington DC, it had the direct impact of influencing the students to develop a mentality of having their carriers entirely based in urban areas (Young, 2009). Medical school groomed students to become researchers that field officers who would go to any grounds for the sake of preservation of humanity. Medical school always brought a conflict between the applications of medicine and...
4 Pages(1000 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Thesis on topic Ugi reaction for FREE!

Contact Us