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In addition, Lorcaserin is used by patients exhibiting at least one weight-related health problem such as hypertension and type-2 diabetes.
In 2006, Phase III of the lorcaserin development program was started, and this involved three main trials: Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) trial, Behavioral Modification and Lorcaserin Second Study for Obesity Management (BLOSSOM) trial and the Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus (BLOOM-DM) trial (Bays, 2011). In general, all these trials showed that the participants showed weight reduction of between 5 and 10%. In all these trials, weight loss was observed after 52 weeks from the period of administering the drug. Overall, this drug has been found to be effective in reducing weigh in patients with and without the type-2 diabetes (Bays, 2011). In addition, the three trials also revealed that most of the patients involved in the study were satisfied with the performance of the drug. Since lorcaserin appears to be ell received by both patients and clinicians, it does offer an alternative to surgery.
Despite the impressive results noted in the trials, a number of side-effects are associated with the use of lorcaserin. These include headache, nausea, dizziness, upper respiratory tract infections and nasopharyngitis (DiNicolantonio, et al 2014). In addition, there is concern that the use of lorcaserin is associated with increased incidences of depression. There is need for further analysis and understanding of the degree to which lorcaserin contributes to these side effects and how they can be minimized.
Obesity is a big issue across the world. It is a major health concern because of the chronic illnesses associated with it. This brochure is therefore intended to enlighten adults, mainly between the ages of 18 and 65 years, on this new development in the treatment of
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