Free

Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Disease - Term Paper Example

Comments (0) Cite this document
Summary
Both gastroesophageal reflux disease as well as Peptic ulcer disease and are common disorders of the gastrointestinal that are bound to be frequently encountered within the clinical environment by practitioners in the medical field. It is imperative for one to be able to clearly…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER91.3% of users find it useful
Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Disease
Read TextPreview

Extract of sample "Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Disease"

Compare and contrast Peptic Ulcer Disease and Gastroesophageal Reflux Disease. Both gastroesophageal reflux disease as well as Peptic ulcer disease and are common disorders of the gastrointestinal that are bound to be frequently encountered within the clinical environment by practitioners in the medical field. It is imperative for one to be able to clearly distinguish one from the other. This paper is going to contrast as well as compare the two gastrointestinal disorders.
Introduction.
Gastrointestinal disorders affect the gastrointestinal walls by corroding them or in the severe cases perforating them. This corrosion is mainly caused by acids in the body which may tend to be overproduced by the respective organs in the body, due to the body failing to balance its production. There are symptoms and diagnosis that may help identify the type of gastrointestinal disorder that one may be suffering from (Kahrilas 2008).
Peptic ulcer disease is the most common ulcer of an area of the gastrointestinal tract, usually acidic and extremely painful. A higher percentage of these ulcers are caused by Helicobacter pyloris. Epithelial cells in the stomach and duodenum secrete mucus in response to epithelial lining irritation. Gastric and duodenal mucosa exist in the form of a gel layer impermeable to acid and pepsin (Kurata et al 1997).
A physiologic balance does exist between gastric acid secretion and gastro duodenal mucosal defense. Peptic ulcers occur due to disruption of the balance between the aggressor factors and defensive mechanisms. The aggressor factors include NSAID’s, H pyloris infection, alcohol, bile salts, acid and pepsin which allow back diffusion of hydrogen ions leading to epithelial cell injury. Defensive mechanisms include tight intercellular junctions, mucus, mucosal blood flow, cellular restitution and epithelial renewal (Kurata et al 1997).
Signs and symptoms
Symptoms of peptic ulcers include abdominal pain, epigastric with severity relating to mealtimes which manifest three hours after taking a meal. Other symptoms include Bloating and abdominal fullness, water brush, nausea and copious vomiting. Pain caused by peptic ulcers may be felt around the navel up to the sternum, this pain normally lasts for a few minutes although it may potentially last for hours and may worsen when the stomach is empty (Kurata et al 1997).
Diagnosis
Diagnosis is mainly established based on the symptoms characteristics. Tests such as endoscopies or barium contrast X-rays help to confirm the diagnosis. An Esophagogastroduodenoscopy (EGD) is usually carried out on patients suspected to be having peptic ulcers (Kahrilas 2008).
Treatment.
Antacids or H2 antagonists are used to treat younger patients with ulcer like symptoms. Patients taking Nonsteroidal anti-inflammatory may be prescribed a prostaglatin analogue to prevent peptic ulcers which happen to be side effects of the NSAIDs. When H pylori infection is present, treatment entails a combination of antibiotics and proton pump inhibitor, occasionally together with a bismuth compound. For perforated peptic ulcers, surgical repair of the perforation is required (Kahrilas 2008).
Gastroesophageal reflux disease
It is a condition that manifests itself through liquid content of the stomach regurgitating into the esophagus. The lining of the esophagus can be inflamed or damaged by the liquid. Acid and pepsin that are produced by the stomach are usually contained in the regurgitated liquid (Kahrilas 2008).
Signs and symptoms.
In adults, symptoms include, heart burn, regurgitation, trouble swallowing and chest pains. In children Gastroesophageal Reflex Disease may be difficult to detect as a result of their being unable to sufficiently describe what they are feeling. In children Gastroesophageal Reflex Disease may cause repeated vomiting, coughing, effortless spitting up, wheezing, inconsolable crying, refusing food and belching or burping (Kahrilas 2008).
Diagnosis.
The current Gastroesophageal Reflex Disease diagnosis is the esophageal ph monitoring which allows for monitoring of Gastroesophageal Reflex Disease patients in regards to their response to medical or surgical treatment. An EGD is done in the event the patient doesn’t respond well to treatment (Kahrilas 2008).
Treatment.
There exist three types of treatment for Gastroesophageal Reflex Disease, these are;
Lifestyle, this may entail the patient avoiding eating meals two hours before bedtime. Sleeping on the left side or with the upper body raised (Kahrilas 2008).
Medication, pharmacotherapy goals are to reduce morbidity in patients with Gastroesophageal Reflex Disease and prevent complications. Agents used to achieve these include antacids, H2 receptor antagonists, proton pump inhibitors and prokinetic agents (Kahrilas 2008).
Surgery, surgical treatment for Gastroesophageal Reflex Disease entails wrapping of the stomach, especially around the upper parts which are located near the esophageal sphincter which helps to strengthen the sphincter and prevent acid reflux (Kahrilas 2008).
Conclusion.
Peptic Ulcer Disease and Gastroesophageal Reflux Disease are disorders of the gastrointestinal walls, though severe if not treated at early stages, they rarely cause deaths. Gastrointestinal disorders can be prevented and in the event of infections, can be treated to full recovery of the patient (Kurata et al 1997).
Reference:
Kahrilas, P.J., (2008). Gastresophageal Reflux Disease.
Kurata Ph.D., John H. Nogawa, Aki N.M.S., (1997) meta-analysis of risk factors for peptic ulcer; Nonsteroidal Antinflammatory Drugs, Helocobucter pylori and smoking. Read More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Term Paper”, n.d.)
Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Term Paper. Retrieved from https://studentshare.org/nursing/1607332-compare-and-contrast-peptic-ulcer-disease-and-gastroesophogeal-reflux-disease
(Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Term Paper)
Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Term Paper. https://studentshare.org/nursing/1607332-compare-and-contrast-peptic-ulcer-disease-and-gastroesophogeal-reflux-disease.
“Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Term Paper”, n.d. https://studentshare.org/nursing/1607332-compare-and-contrast-peptic-ulcer-disease-and-gastroesophogeal-reflux-disease.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Disease

Gastroesophageal reflux disease

... severe a person would face the problem of bleeding, ulcers, strictures and may possibly develop Barrett Esophagus (Kumar et al 2005; Hall & Guyton 2006). References KUMAR, V., ABBAS, A. K., FAUSTO, N., ROBBINS, S. L., & COTRAN, R. S. (2005). Robbins and Cotran pathologic basis of disease. Philadelphia, Elsevier Saunders. Hall, J. E., & Guyton, A. C. (2006). Guyton & Hall physiology review. Philadelphia: Elsevier Saunders. Top of Form Dore, M. P., Maragkoudakis, E., Pedroni, A., Tadeu, V., Delitala, G., Graham, D. Y., Malaty, H. M., ... Realdi, G. (August 01, 2008). Diet, lifestyle and gender in gastro-esophageal reflux disease. Digestive Diseases and Sciences, 53, 8, 2027-2032. Bottom of Form Top of Form... ?Gastroesophageal...
1 Pages(250 words)Research Paper

GASTRO ESOPHAGEAL REFLUX DISEASE

...? Gastroesophageal Reflux Disease Gastroesophageal Reflux Disease Introduction Gastroesophageal reflux (GER) refers to a condition caused by regurgitation of the gastric acid into the esophagus. The condition is a common presentation in adults recognized by a burning sensation in the chest. Aspiration of gastric contents leads to a pathological process referred to as gastroesophageal reflux disease (GERD). Patients experience gastrointestinal and respiratory complications, which develop to diseases like esophageal cancer when left untreated. GERD is a risk factor for Barrett’s esophageal (BE), which also predisposes patients to esophageal adenocarcinoma (EAC). Patients diagnosed with GERD require proton pump inhibitors therapy... of fibers...
5 Pages(1250 words)Essay

Gastritis and Peptic Ulcer Disease in Children

...Response Paper "Gastritis and Peptic Ulcer Disease in Children," by U. Blecker and B.D. Gold This paper takes a look of the occurrence of gastritis and peptic ulcer disease as it occurs in children. The paper notes that it is not common, but that several factors can lead to its development (Blecker and Gold, 1999). First of all, the paper points out that several conditions can lead to this development in children. First is an overproduction of acid secretion. Second are bicarbonate mucous barriers. Third is genetics. Overuse of ibuprofen and aspirin are often the cause of these conditions and should be avoided at all costs. If not,...
1 Pages(250 words)Article

Gastroesophageal Reflux Disease

...was given continuously and on demand as compared with ranitidine(continuous 80.2%, on - demand 77.8% vs ranitidine 47.0%, p < 0.001). They concluded that esomeprazole 20 mg once daily continuously and on demand were more effective than ranitidine continuously for maintaining QoL. Zhang et al., (2002)illustrated that pharmacological inhibition of transient lower oesophageal sphincter relaxations (TLOSRs)is helpful in the treatment of reflux disease. They studied the effect of baclofen in gammaaminobutyric acid (GABA) receptor type B-agonists on TLOSRs and gastroesophageal reflux in patients with GERD. The study included 20 patients (15 men; 5 women) with GERD. Their...
18 Pages(4500 words)Essay

Peptic Ulcer

...) GIT endoscopy is a key to diagnosis of peptic ulcer disease, complication and for differential diagnosis from other causes of dyspepsia. In addition, endoscopic healing is the gold standard in treatment evaluation. Upper GIT double-contrast radiography may be of equal diagnostic accuracy. However, radiological studies are not as sensitive as endoscopy especially for the diagnosis of small ulcers (less than 0.5 cm). Further, radiological studies do not allow biopsy needed for differential diagnosis, ruling out malignancy or access to H pylori infection diagnosis. The main indication for CT scan is when considering other associated condition and chest...
2 Pages(500 words)Essay

Peptic Ulcer Diseases

... Peptic ulcer diseases are usually treated with antacids, proton-pump inhibitors (PPIs), and Histamine2-blockers (H2-blockers). Proton pump inhibitors work by blocking the final step of acid production and inhibiting gastric acid secretion by being converted to active metabolites that irreversibly bind and inhibit H+/K+ ATPase, an enzyme on the surface of gastric parietal cells (James, 268). Meanwhile, Histamine2-blockers inhibit gastric acid secretion by inhibiting histamine action at H2-receptors of the parietal cells (James, 269). Antacids work by neutralizing hydrochloric acid and reducing pepsin activity. Antibiotic therapy prescribed to rule out Helicobacter pylori in Mr. P’s gastric ulcer includes amoxicillin (Amoxil... ...
1 Pages(250 words)Essay

Gastroesophageal reflux disease (GERD)

...Health Sciences and Medicine: Gastroesophageal Reflux Disorder Introduction/Background A more serious form of gastroesophageal reflux (GER) is the gastroesophageal disease (GERD) which is more common. It is with the spontaneous opening of the lower esophageal sphincter (LES) that gastroesophageal reflux (GER) occurs. It is either for varying periods that the opening occurs, or that it does not closes up properly because of which the stomach contents rise up into the esophagus. Acid reflux or acid regurgitation is the other name, which has been given to GER. This name is given because acids- otherwise known as acid juices, rise up with the food. The tube...
4 Pages(1000 words)Essay

Pancreatitis and Peptic Ulcer

...Pancreatitis and Peptic Ulcer Pancreatitis is the inflammation of the pancreas, while a peptic ulcer is an open sore in the lining of the stomach or duodenum. The two diseases have different causal factors, symptoms, possible complications and modes of treatment. Pancreatitis and Peptic Ulcer. Pancreatitis is the inflammation of the pancreas, an organ which releases digestive enzymes and hormones that become active when they reach the small intestine. When these enzymes become active in the pancreas itself, they eat through the pancreatic tissue, damaging the organ and its blood vessels. This is called pancreatitis. Pancreatitis is caused by autoimmune problems, damage to the pancreas, blockage of the pancreatic ducts... ,...
1 Pages(250 words)Essay

Gastroesophageal Reflux disease

...Gastro-oesophageal reflux disease affiliation A Gastro-oesophageal reflux disease (GERD) is a term that refers to the digestive problem that is associated with defects of the lower oesophageal sphincter. This condition results into a reflux of the gastric contents back to oesophagus, which provokes clinical signs and symptoms that impair life. Symptoms of the disease include regurgitation and heartburn; other symptoms may be pain during swallowing, stomach pain and choking sensation. The Pathophysiology of GERD is multifactorial since it incorporates relaxation of the lower oesophageal sphincter as well as abnormalities of pressures...
1 Pages(250 words)Essay

Gastroesophageal Reflux Disease

...evaluation. Doctors can use a variety of procedures and tests in examining a chronic heart burn patient. The earlier testing phase can encompass an upper Gastrointestinal Series, which is a special X-ray which shows the stomach, duodenum and the esophagus (Joel & Ritcher, 2014). This test may provide limited information on the possibility of reflux but is helpful in ruling out other diagnoses such as peptic ulcers. Endoscopy is also important for chronic GERD patients. It can show irritation or inflammation of the esophageal tissue lining. If Endoscopy presents questionable or abnormal results, an esophageal lining biopsy may be helpful. Esophageal impedance and manometric studies which...
2 Pages(500 words)Case Study
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Term Paper on topic Compare and Contrast Peptic Ulcer Disease and Gastroesophogeal Reflux Disease for FREE!

Contact Us