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MRSA - Research Paper Example

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“MRSA" Article-"Klein, E., Smith, D. L., Laxminarayan, R. (2007). Hospitalizations and Deaths Caused by Methicillin-Resistant Staphylococcus aureus, United States, 1999- 2005. Emerging Infectious Diseases, 13(12), 1840- 1846". Introduction Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA) colonization, results in severe infections in humans…
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Download file to see previous pages... MRSA is a nuisance in hospital for the patients with open wounds or on invasive devices and bothersome for immunocompromised patients. The study reports MRSA to be the major cause of illness and mortality in the hospitalized patients and thereby enhances the burden of hospitalization cost. The research reports the mortality associated with MRSA between 1999- 2005. However, the article does not report the variation of cases in different hospitals to highlight the need of intervention required in a particular hospital to rule out the cause and take steps to eradicate MRSA as done in the study carried out by Hardy et al, (2007). The article considered evidence based research to highlight allocated resources to deal with MRSA and emphasize on the decision of policy makers to adopt control measures, but the article does not state the control measures to be adopted in different hospital settings to check spread of nosocomial spread of MRSA. On the other hand the study carried out by Hardy et al, (2007) specify the microbiological identification of patients followed by the isolation of such cases to prevent cross-infection together with application of mupirocin and skin disinfectant in order to remove the chances of any carriage. The article emphasize on thorough screening and isolation. According to Hardy et al, (2007), the interventions to control MRSA infection are poorly designed and including nurse cohort in bays. The screening method that is suggested by Hardy et al, (2007) directly implicate the molecular methods for detection of MRSA such as multiplexed PCR primers to detect the presence of gene (mecA). Methodology The methodology adopted was based on estimated incidence, i.e. the number of hospitalized cases with S. aureus-related discharge. The Surveillance Network (TSN) Database- is an electronic repository of susceptibility test is utilized to test the drug resistance patterns. However, the study highlights NHDS report on the mortality of the patient but the reason of mortality was not specified. The report estimated only those mortality cases which were involved with MRSA. On the contrary, study carried out by Hardy et al, (2007) was systematically planned involving socio-economic, ethnic as well as age characteristics. It involved seven surgical wards encompassing general surgery, vascular, thoracic, ENT, trauma and orthopedic as well as urology. The study also had inclusion and exclusion criteria of the cases in contrast to the study carried out by Klein et al, (2007) which does not have any exclusion criterion nor does the study involved sampling procedure. On the other hand, study carried out by Hardy et al, (2007) involved nasal samples as they can be procured easily and have 84% sensitivity. The results procured were immediately conveyed to the staff of the concerned departments to have laboratory protocol and for patient information and communication. All these actions such as data collection, data analysis, sample size, economic analysis, modelling were swiftly performed to control the infection. All these methods were lacking in the study carried out by Klein et al, (2007). Discussion According to Klein et al, (2007), antimicrobial drug-resistant illnesses inflict larger costs as compared to the susceptible infections caused for instance infection caused by Staphylococcus ...Download file to see next pagesRead More
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