The incidence of cardiovascular risk factors in the form of diabetes, obesity, dyslipidaemia and hypertension are often considered as the metabolic syndrome. It is reported that almost 29 percent of global deaths occurring is from the Cardio vascular diseases with majority of…
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of the deaths reported from United States due to Coronary vascular disease is also 30 and this is reported maximum for the age groups above 65 (United States, 2006)
Among various pathogenic factors, insulin resistance and visceral obesity are considered most significant. (Duvnjak and Duvnjak, 19- 24) . The observed metabolic abnormalities are due to insulin resistance in muscles and surrounding adipose tissue along with the adverse impact on tissue by compensatory hyperinsulinaemia, which is insulin sensitive (Duvnjak and Duvnjak, 19- 24). In addition, abdominal adiposity is also considered a high risk for cardio vascular diseases (CVD). Also, the increasing obesity is found to decrease adiponectin that has important cardiometabolic actions (Bray et al, 30-40). Significant breakthroughs have also been achieved in understanding the key initiators for coronary artery disease. The initiation and progression of atherosclerosis has been found to be associated with leptin. Studies have also shown that plasma leptin concentration has direct relation to the incidence of coronory artery disease and thus could be used as a risk indicator for the development of the disease (Dubey et al, 124 - 128).
. It is clear that the role played by obesity in the cardiometabolic risk is very vital for the development of treatment strategies for the patients with a high risk for cardio vascular diseases (CVD).A critical role played by adipocytokines between insulin resistance and cardiovascular disease has been established. It is also anticipated that effective interventions to improve the functions of endothelial or adipose tissues could significantly reduce the occurrence of cardiovascular events in the obese individuals with metabolic syndrome (Hamdy, 231 - 241). One of the effective ways to treat the people with high cardiovascular risk is through the various lifestyle modifications like restricted calorie intake and increased physical activity (Hamdy, 231-241). The impact of
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GOUT Word Count 2766 INTRODUCTION Gout is a metabolic disorder classically represented as acute inflammatory monarthritis (Rott & Agudelo, 2003); that is known to be initiated by the crystallization of uric acid (UA) within the joints. Uric acid is the end product of metabolism of purine.
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As expert scientists prove, the use of growth hormones in food animals poses a potential risk to consumers’ health because hormones found in meat from these animals can disrupt the consumer’s hormone balance, cause development problems, interfere with the reproductive system and even lead to the cancer development.
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