GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE - Essay Example

Comments (0) Cite this document
Summary
Pharmacogenetics is the new line of research in pharmacy industry that is increasing our understanding of drug interactions. This is the prime area of research of pharmacogenetics…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER98.8% of users find it useful
GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE
Read TextPreview

Extract of sample "GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE"

Download file to see previous pages While the newer drugs are safer with a higher therapeutic index, the problem does not go away for the 6% of the Caucasian population that is not able to metabolize drugs properly. (Wolf and Smith, 1999, pp 366) Safer drug regimes do not necessarily obviate the possibility of adverse drug reactions or idiosyncrasies. Adverse drug reactions are seen to be a high occurrence with 20, 000 cases reported annually in the UK. The consequences can be fatal and therefore, it is important to carry out informed decision by considering each patient prior to medicating. Still even with the best decision making processes, there is no guarantee how effective a drug will be on a patient. In the US the adverse drug reactions are termed the fourth highest cause of death. (Wolf and Smith, 1999, pp 367) There are estimates that 1 in every 15 individuals hospitalized suffers from adverse drug reactions. Around 106, 000 individuals die annually and 2.2 million are injured each year due to adverse drug reactions. (Wolf et al, 2000, pp 987)

The genetic variation and responses are a new line of investigation in this regard. However, the genetic difference in the response to various drugs is an element that came later into play. Before these, factors such as age, body size, diet, gastrointestinal absorption, compliance with therapy and the characteristics of the drug were considered for each individual. These are still one of the primary considerations for any physician prior to drug dosing. The genetic component came into being by studying patterns of drug behavior in different populations, especially syndromic patients and in those who suffered from cancer or metabolic diseases. The pharmcogenetic variation was a very important discovery in the case of oncology. (Brice and Sanderson, 2006, pp 109) The variable responses of the drugs and their toxic effects have been especially vexing for physicians for treating cancer patients, whose resistance to external insults is already reduced considerably.
For every drug to be therapeutically effective, it must be present in the body in a particular concentration for a fixed amount of time, and then should be able to be metabolized or removed from the system before it accumulates within the body. The individual responsiveness of a drug in the body is not possible to carry out in each individual. However the advent of genetic analysis and therapies are making this a reality in the clinical practice. While still in the formative phases, the pharmacogenetics holds major potential in predicting adverse reaction cases, and the thereby preventing them. While therapeutic synchronicity and adversity among different drugs is well documented and reported, the genetic predisposition at the individual area was not documented as thoroughly. (Wolf and Smith, 1999, pp. 367) Now researchers understand the role of genetics in the predisposition and nature of the disease progress, and how it can be prevented or treated accordingly.
Media is playing an important role in promoting the use of genetics and its role in treating disease, while these facts are true, the media often fails to highlight the complexity of the issue. Pharmacogenetics is not simple identification of genes and then creating ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE Essay”, n.d.)
Retrieved from https://studentshare.org/miscellaneous/1526918-genetically-targeted-drug-therapy-what-is-the-future
(GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE Essay)
https://studentshare.org/miscellaneous/1526918-genetically-targeted-drug-therapy-what-is-the-future.
“GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE Essay”, n.d. https://studentshare.org/miscellaneous/1526918-genetically-targeted-drug-therapy-what-is-the-future.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE

Antibody targeted drugs for cancer therapy

...(ADEPT). Cancer Biother Radiopharm., 18(3), 339-53. Bodey, B., Bodey, B. Jr, Siegel, S.E., Kaiser, H.E. (2000). Genetically engineered monoclonal antibodies for direct anti-neoplastic treatment and cancer cell specific delivery of chemotherapeutic agents. Curr Pharm Des., 6(3), 261-76. Bodey, B. (2001). Genetically engineered antibodies for direct antineoplastic treatment and systematic delivery of various therapeutic agents to cancer cells. Expert Opin Biol Ther., 1(4), 603-17. Chari, R.V. (2008). Targeted cancer therapy: conferring specificity to cytotoxic drugs. Acc Chem Res., 41(1), 98-10. Damle, N.K., Frost, P. (2003)....
20 Pages(5000 words)Dissertation

Targeted Media and Audience

...W’s (where, who, why, what, when) (Slaunwhite, 2010 p6). This paragraph will simply summarize the press release, and provide a hook that appeal to the audience. Body This part will expand on the hook provided in the lead paragraph. It will employ inverted pyramid strategy where the most relevant information and quotes will be provided in the first paragraphs, and less weighty quotes provided in the subsequent paragraphs (American Institute of Architects, 2008 p56). Company Boilerplate This paragraph will provide brief information about Le Tour de Sandwich, including its activities, short history, products and services (Cook, 2011 p67). Contact Information Name, Title, Phone, Email. Targeted Media and Audience...
5 Pages(1250 words)Essay

Behavior Couples Therapy for Alcoholism and Drug Abuse

...? Behavior Couples Therapy for Alcoholism and Drug Abuse Behavior Couples Therapy for Alcoholism and Drug Abuse Behavior couples therapy comprises multiple sessions of therapy intended foe a couple when either or both partners exhibit a problem with alcohol or drugs. The primary objective of this type of therapy is to offer help to couples or partners who are living together. According to psychologists, the support from a partner can motivate a patient to abstain from the use of drugs or alcohol. The patient’s partner commits to offer support to his or her partner. Moreover, the...
5 Pages(1250 words)Research Paper

Targeted Work Class

...? Human Resource Strategy [Sur Human resource strategy attempts to provide a practical framework in which experts may help develop human resource strategies in line with their organizations’ corporate planning processes. It proposes a four step approach involving: developing of a strategic framework; generating of HR mission statement; application of a SWOT analysis; and making strategic planning decision between human resource options. By definition, human resources strategy is a process that identifies current human resources and future human resources needs an organization to achieve its goals. Human resource planning should serve as a link between human resources management and the overall strategic plan of the...
4 Pages(1000 words)Research Paper

Targeted Work Class

...? Targeted Work Targeted Work After carefully assessing the work processes at Wal-Mart, I realized there was the need for the company to be more responsive to customers by improving their processes and systems so as to ensure urgent and precise actions are taken in responding to their customers’ needs. In order to adequately do this, Wal-Mart needs to emphasis on three key objectives. One is the fulfillment of specific customer requirements; second is ensuring that they achieve high levels of customer satisfaction and; thirdly, they should try to adapt to the needs of business and market environments that change every day. Wal-Mart is capable of achieving these objectives while still maintaining and...
4 Pages(1000 words)Research Paper

Targeted Messaging

...are based on attracting men and playing with their psychology. Studies indicate that media messages flashed across to the target audience help gender related activities to become prominent. A study based on women indicated that women even learn before their marriage, the overall mechanics of the wedding and how this is going to affect them. (Daws, 2009). This clearly indicates that media plays significant role in shaping the personal identity in relation with the messages portrayed regarding gender roles. My own personal identity, if viewed within the perspective of the advertisements and messages depicted in both the magazines, therefore is largely shaped by the way I am portrayed i.e. as the way how my gender is...
1 Pages(250 words)Essay

Targeted Organization Summary

...Targeted organization summary Shell Company is a multinational organization, well established with a history of stability. It therefore presents employees with job security. The company’s establishment provides for good psychological working environment that facilitate performance and career development. Its multinational scope also presents employees with opportunities to international ventures. The scope of work at the company is also interesting. Operations at Shell that include industrial extraction of petroleum provide a public health student in industrial hygiene with an employment opportunity that matches academic qualifications. Besides, the company’s scope of work that includes interaction with workers in...
1 Pages(250 words)Essay

Drug Therapy handout

...Drug Therapy Handout Drug Therapies Fill in the following boxes by identifying and describing four categories of drug therapy. Give an example of a drug in each category and state which disorder it is used to treat. Discuss how the drug works, and include any undesirable side effects. Save this document and type directly onto the document and into the boxes. The boxes will expand to accommodate what you write. Submit as an attachment to the appropriate drop box. Category of Drug Therapy Example of a drug in this category and the disorder it is used to treat How the drug works, and any undesirable side effects Chemotherapy Cyclophosphamide (Cytoxan, Neosar) Used for the control and/or treatment of Breast Cancer. The drug can... be...
2 Pages(500 words)Essay

The future technologies of drug delivery systems

...strategies. For instance, in gene therapy technology, a virus is used as a vector for the delivery of corrective and active genes into the cell of the patient. However, if the vector attaches itself to the genes of the cell, it can result into uncontrolled genetic alterations thus lead to carcinogenesis. It is therefore, recommended that if the promise of RNAi therapies is to achieved, researchers must develop ingenious systems that offer protection to the small interfering RNAs (siRNAs) in the bloodstream. Instead, these small interfering RNAs must be targeted within the right cells (Allen & Cullis, 2004). The major advances in drug delivery systems...
8 Pages(2000 words)Essay

Targeted tax

...Taxation Introduction Tax is a obligatory payment made by each and every individual to the government. The money paid as tax is used in paying for the provision of public services. The United Federal States has come up with certain tax policies that seem to be quite oppressive to the citizens of America. The tax policies that have been implemented go against the principles of any sound taxation policy. Impacts of Taxation They have gone against the first principle of taxation that is to achieve equality among the citizens of America (Lymer, 2013). The tax policies that have been implemented seem to favor one of the economic groups at the cost of other people who are less economically empowered. They have also lowered the taxes... Introduction ...
3 Pages(750 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Essay on topic GENETICALLY TARGETED DRUG THERAPY: WHAT IS THE FUTURE for FREE!

Contact Us