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"Inhibitor Empagliflozin at a Dose of 25mg" paper argues that a glucuronic treatment with the novel SGLT2 Inhibitor Empagliflozin at a dose of 25mg once daily significantly increases the odds of achieving an hba1c target of <7% compared to placebo in adults suffering from diabetes mellitus type II…
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Diabetes is among the chronic progressive diseases against which the healthcare sector contends, not only to treat but also to prevent, manage and control. In the UK alone, the condition affects more than 2.6 million people (Grempler et al., 2013). The world figures are even more worrisome, standing at 366 million patients. Demographic and prevalence data show that chronic diabetes mellitus type II is perhaps the hugest challenge not only for healthcare practitioners but also for policymakers such as the local and regional governments, through the Ministry of Public Health (Wright, 2001). To effectively address these negative effects of diabetes mellitus type II, it is of the essence that healthcare practitioners recognise and understand the key factors involved in the prevention, pathogenesis and treatment of the condition (Bailey & Day, 2010). Regarding the disease’s pathogenesis, the key elements are; the role of peripheral insulin insensitivity or insulin resistance and impaired insulin secretion by the B cells of the pancreas. These are the two factors that result in hyperglycaemia in diabetics. If this glycaemia is detected early, managed well and controlled effectively, it would become easier to detect and prevent diabetes-related micro- and macro-vascular complications (Williams et al., 2002).
In preventing, controlling, managing and treating diabetes mellitus type II, the main objectives should be the prevention and elimination of the disease and its signs and symptoms. In worse cases of the disease, healthcare practitioners handling diabetics need to at least slow down the development of other complications related to diabetes mellitus type II. By controlling glycaemia and blood pressure, eye and kidney complications related to diabetes mellitus type II can be brought under control (Grempler et al., 2013). These complications are referred to as microvascular whereas the side effects of coronary, peripheral vascular and cerebrovascular are macrovascular complications associated with diabetes mellitus type II.
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