StudentShare
Contact Us
Sign In / Sign Up for FREE
Search
Go to advanced search...
Free

Endocrine Disorder Acromegaly - Essay Example

Comments (0) Cite this document
Summary
The article under the title "Endocrine Disorder Acromegaly" discusses the endocrine system, which unconsciously carries out a wide range of processes through chemical messengers called “hormones”. Metabolism, moods, and growth development is mainly regulated by these hormones…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER97.9% of users find it useful
Endocrine Disorder Acromegaly
Read TextPreview

Extract of sample "Endocrine Disorder Acromegaly"

Answer 1This article mainly discusses the endocrine system, which unconsciously carries out wide range of processes through chemical messengers called "hormones." Metabolism, tissue function, moods and growth development is mainly regulated by these hormones. This signaling system utilizes blood vessels, which release glands directly into the blood stream, and then they are moved throughout the body. Alexander, Fawcett and Runciman (2006. p.162) states that, "Disorders of the endocrine system may be categorized most simply as those involving over production (hyper-secretion) and those involving under production (hypo-secretion). The hyper/hypo secretion of hormones effect and disturbs the whole balance of the system. (Alexander, Fawcett and Runciman, 2006. p.162) Acromegaly arises in a human body, when pituitary gland continuously hyper secretes the growth hormone, causing the hormonal disturbance. Endocrine and Metabolic Diseases (2008) writes that, "Excess growth hormone stimulates hepatic secretion of insulin-like growth factor-I (IGF-I), which causes most of the clinical manifestations of acromegaly."
Answer 2: The physiology and anatomy of the endocrine system in acromegaly includes that of the growth hormone while of the nervous system includes that of the pituitary gland. Growth hormone is a protein which most commonly contains 191 amino acid residues and has two main forms known as 20 K and 22 K. It is secreted in a pulsatile fashion from the anterior pituitary gland and is fundamental for its physiological effect (Varela-Nieto & Chowen, 2005).



Pituitary gland is a pea-sized gland attached to the hypothalamus by a stalk and located at the base of the brain (Alexander, Fawcett, & Runciman, 2006). One of the main functions of this gland is to regulate the levels of GH and IGF-1 in the blood and also homeostasis in the body. Some of its functions include regulation of blood pressure, thyroid gland function, metabolism and secretion of ADH among others.
Answer 3:Successful treatment of acromegaly not only reduces the levels of GH and IGF-1 to normal but also alleviates the pressure from the growing pituitary hormone exerts on the areas of the brain. Dopamine analogues such as bromocriptine does the latter but, somatostatin analogues like octreotide and lanreotide does both (Hansen, 2006). Other treatments include surgery and radiotherapy for reducing the size of the tumor (Une, 2007). Combining dopamine analogues with somastostatin analogues produces more effective results than either does alone. The somatostatin analogues effect on glucose homeostasis is minor and this increase was controlled by administrating octreotide.
Answer 4: The Endo's products continue to contribute significantly to future growth of pharmaceutical industry. Present research is investigating the safety and effectiveness of this new drug along with its dosage, schedule and combinations of somatostatin analogs and GH receptors. The suggestions for the patients of acromegaly in this are that it is safe for the patient to use this new drug because it is working well with the earlier first medication groups of SSAs and Dopamine agonists. Bankhead, C. (2009) quotes Catherine Lesage, who writes that, "The activity we observed suggests this compound should be effective in normalizing the hormonal profiles of patients with acromegaly."
The future use of this drug will take an account of the presently carried out research which insists that there is a good interaction between these drugs. Dr. Lesage was quoted in the article who writes that. "Targeting both receptors might be more effective than focusing on one." The observations and research also "provided a rationale for development of BIM 23A760, a chimeric compound that contains structural elements of somatostatin analogs and dopamine agonists." (Bankhead, C. 2009).




































References

Alexander, M. F., Fawcett, J. N., & Runciman, P. J. (2006). Nursing practice: An Introduction. USA: Elsevier Health Sciences.

Bankhead, C. (2009). ENDO: New Acromegaly Drugs Show Promise. Retrieved June 29, 2009, from http://www.medpagetoday.com/MeetingCoverage/ENDO/14784


Endocrine and Metabolic Diseases (2008). Acromegaly. Retrivced June 29, 20009, from http://www.endocrine.niddk.nih.gov/pubs/acro/acro.htm

Hansen, H (2006). Somatostatin Analogs for HRPCa. Retrieved June 29, 2009, from http://www.hrpca.org/somatostatin.htm

Une, K. N. (2007).Endocrinology. Retrieved June 29, 2009, from http://www.medstudents.com.br/endoc/endoc8.htm

Varela-Nieto, I, & Chowen, J. A. (2005). The Growth Hormone/insulin-like Growth Factor Axis During Development. Switzerland: Birkhuser. Read More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Endocrine Disorder Acromegaly Essay Example | Topics and Well Written Essays - 500 words”, n.d.)
Retrieved de https://studentshare.org/health-sciences-medicine/1511936-endocrine-disorder-acromegaly
(Endocrine Disorder Acromegaly Essay Example | Topics and Well Written Essays - 500 Words)
https://studentshare.org/health-sciences-medicine/1511936-endocrine-disorder-acromegaly.
“Endocrine Disorder Acromegaly Essay Example | Topics and Well Written Essays - 500 Words”, n.d. https://studentshare.org/health-sciences-medicine/1511936-endocrine-disorder-acromegaly.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF Endocrine Disorder Acromegaly

Air Pollution or Endocrine Disrupters

... factor to consider in the assessment of the impact of disruptors is the fact that individual differences in a person’s metabolism and body composition may affect the disruptor’s impact on the human body. Therefore, the impact of a disruptor is distinct to each person, depending on individual differences in metabolism; body composition; degradation of body fluids and tissues; genetic polymorphisms; chronic exposure to low amounts of disruptors; latency between exposure to the disruptor; and the occurrence of clinical disorders (Diamanti-Kandarakis, 2009). Environmental Protection Agency There are various pros and cons in the EPA setting forth screening for endocrine disruptors before they even enter the body. Animal tests proposed...
10 Pages(2500 words)Research Paper

Endocrine Disorders

...? Endocrine Disorders Endocrine Disorders Hormonal system plays a vital role in performing bodily functions. Hormones are chemical agents which help in different bodily reactions. Hormones are secreted by glands in our body. Thyroid is one of the most important gland in our body which produces two main hormones known as thyroxine and triiodothyronine, store them and then secrete them whenever they are needed in the body. The main function of these hormones is to control the metabolic rate of the body. The production and secretion of these hormones from thyroid gland are regulated by another hormone thyroid stimulating hormone (TSH) which is released from the anterior lobe of the pituitary gland. In some diseases abnormalities occur...
3 Pages(750 words)Term Paper

Endocrine Effects of Marijuana

... that govern emotion, memory, and aggression. The findings were taken from using magnetic resonance imaging to scan the brain of subjects who smoke for more than five joints a day in a minimum of ten years and compared them with non-substance takers (Stacey 1997, p. 62-63). Regular cannabis smokers had a 12 % smaller hippocampus and a 7% smaller amygdala. The hippocampus is involved with emotion and memory, while the amygdala regulates fear and aggression. Cannabis users are also reported to tend to fare worse in tests of verbal memory and a likewise likelihood for a low-level symptoms of psychotic disorders such as schizophrenia. The substance is found to cause fleeting schizophrenia-like symptoms which range from suspiciousness...
8 Pages(2000 words)Assignment

Endocrine Disruptors

...Endocrine Disruptors The harmful effects of exposure to environmental pollutants on reproduction and development in wildlife populations have been acknowledged and reported in the scientific literature for many years. Some reported reproductive disorders in wildlife have included morphologic abnormalities, eggshell thinning, population declines, impaired viability of offspring, altered hormone concentrations and changes in socio-sexual behaviour. However, what has been elusive is how these chemicals exert their influence on the reproductive and developmental process of wildlife animals (CLS, 1999; Colborn, 1999). However, recent studies have shown that the reproductive and developmental anomalies caused by these chemical are induced...
4 Pages(1000 words)Essay

Endocrine System: Facts, Functions

... Endocrine System: Facts, Functions Abstract. The endocrine system works in tandem with the brain in the control and coordination of bodily functions. It consists of the endocrine glands, hormones and receptors in the target cells. The major endocrine glands are the pituitary gland, the pineal gland, the thyroid gland, the parathyroid gland, the adrenal gland, the pancreas, the gonads (ovaries and testes), the thymus and the hypothalamus. Hormones are chemical messenger secreted by the endocrine glands. Hormones target receptors in particular cells or organs and effect changes in cell activity. Imbalances in hormone levels cause endocrine disorders. The Endocrine System. The control and coordination of all bodily...
9 Pages(2250 words)Term Paper

Endocrine Deficiency: Case Study

... Endocrine Deficiency: Case Study A woman in her late fifties was found unconscious and admitted to hospital. On investigation, it transpired that she had felt unwell for some time, and had felt dizzy and occasionally had episodes of vomiting. Over the past few days, she had been feeling rather tired and sleepy. On testing, her urine was negative for glucose and ketones. Her blood count was normal, and there was no evidence or history of trauma to the head. The following tests were performed:  Plasma value Recorded value Reference value  Na 118 mmol/L 135-145 mmol/L  K 5.90 mmol/L 3.6-5.0 mmol/L  Cl 85 mmol/L 98-106 mmol/L  CO2 20 mmol/L 23-30 mmol/L  Urea 24.5 mmol/L 3.0-8.0 mmol/L...
7 Pages(1750 words)Essay

Endocrine system

... The Endocrine System Thyroid glands forms one of the largest endocrine systems in the body, it is found around theneck region and is responsible for the production of hormones thyroxine and triiodothyronine. The hormones are important during fuel metabolism that drives energy synthesis as well as protein expression in living organisms (Yadav 166). The syntheses of these hormones are from iodine and tyrosine and extend to regulation of calcium homeostasis through the production of calcitonin (Yadav 156). Unregulated production of thyroid glands hormones can lead to physiological departure leading to many complications in the body. The conditions...
1 Pages(250 words)Case Study

Endocrine System

... in PTSD patients are more sensitive to cortisol, and that there are more of these receptors than in normal patients. This greatly increased sensitivity to cortisol means that its negative feedback effects on the HPA axis are magnified (Jaffee et al.) It is also possible that the hypoactivity often seen with PTSD, chronic pain, chronic fatigue, and other chronic stress states is not related to the stress disorders at all, but is due to a co-morbidity with major depressive disorder (Yehuda et al.). This hypothesis is reasonable due to the fact that life with a chronic stress disorder is often very difficult for the patient, and being unable to successfully live a normal life could easily result in major depression. The endocrine system...
1 Pages(250 words)Essay

Respiratory, Endocrine, Urinary Systems

... Press. Besharse, J & Bok, D. (2011). The Retina and Its Disorders. New York: Academic Press. Buzzle. (2014). Synovial Membrane. Retrieved from http://www.buzzle.com/articles/synovial-membrane.html Carter, S. (2004). Endocrine System. Retrieved from http://biology.clc.uc.edu/courses/bio105/endocrin.htm Chun, V & Go, D. (n.d.). Pulmonary Circulation and Systemic Circulation. Retrieved from http://www.slideshare.net/MadeleineSi/pulmonary-systemic-circulation-10655449 Dissection Exercise. (n.d.). Fetal Pig II. Retrieved from http://coursecontent.nic.edu/klchamberlain/biol175kc/LabContent/LM_Exercises_pdf/12_Fetal_Pig_II.pdf Franklin Institute. (2014). Blood. Retrieved from http://www.fi.edu/learn/heart/blood/blood.html Human Biology. (n.d...
12 Pages(3000 words)Coursework

Endocrine System Disorders: Diabetes

...A Case Study on Diabetes al Affiliation A Case Study on Diabetes In the presented case, Lila is diabetic and her diabetesis insulin dependent. A look at her diet shows that she has not been in a healthy diet since she was young. At the moment, Lila is overweight and at the same time, she is diabetic. Thinking of this condition might affect Lila even more. She might turn into more eating and poor dietary measures, which will only increase her size. She might even hate anyone who tries to warn her about her weight. This is exactly what happened when she was young when she chose to follow the healthy eating lifestyle presented by her mother. Like some part of the argument presented by Peter Attia, Lila’s diabetes might have been... Case Study...
1 Pages(250 words)Essay

Mental Disorder and Criminal Offending

One of the notable cases that may be cited in the history of Britain is that of Peter Fuller, who was also known as Jack the Ripper and who has now been identified as a schizophrenic. Ainsley has detailed the stories of several women such as Mary Ann Brough, who slashed the throats of all her six children in an insane rage. (Ainsley, 2000).
Modern instances of horrific crimes committed by people who are mentally ill would include cases such as that of Thomas Hamilton who entered a classroom one day and killed the Mayor and sixteen children and injured several others (www. rotten.com) and that of Horret Campbell who entered a primary school and lashed out at the children with a machete. (Verkaik, 2001). Such horrific crimes re...
10 Pages(2500 words)Assignment

History of the Mental Illness: Bipolar Disorder

...History of the mental illness: Bipolar disorder Bipolar disorder also known as manic depression is a of mood disorders in which the person experiences states or occurrence of depression or mania, hypomania, or mixed states which severely disabling psychiatric condition. The difference between bipolar disorder and unipolar disorder, also called major depression, is that bipolar disorder involves energized or activated mood states in addition to depressed mood states. Mood swings cause impairment not only in ones mood, but also in ones energy level, sleep pattern, activity level, social rhythms and thinking abilities (Wikipedia, 2006). Estimates for the lifetime risk of developing bipolar disorder range from 0.6 per cent to 1.2 per cent...
6 Pages(1500 words)Assignment

Curing Attention Deficit Disorder

Media Article: In “Curing Nature Deficit Disorder”, Patrick Tucker investigates the claim made by Richard Louv in his book “Last Child in the Woods” to the effect that when a child is deprived of adequate "nature exposure", i.e., support, care, attentive parenting and social interaction, his/her physical and mental health will be negatively impacted. This can result in, diminished sensory perception, attention deficit and higher rates of physical and emotional illness. Louv further argues that getting back to nature may help children cope with ADHD. He supports his argument by citing several studies that provide strong evidence that outdoor activities alleviate two ADHD symptoms: inattentiveness and fluctua...
6 Pages(1500 words)Term Paper

Disease and Genetic Disorder for the Human Body Systems

Electrocardiography and angiography are frequently used to diagnose the disease. As a treatment, coronary artery bypass graft surgery (CABG) is performed if the number of affected arteries and the extent of the blockage is high. Low-fat diet (especially saturated fats) maintain healthy body weight and regular physical activities help in preventing the disease.
Hypertrophic cardiomyopathy is a genetic disorder in which the proteins of the cardiac muscles become thick (hypertrophy) results in sudden death at any age. This is caused by the mutations in the genes responsible for myosin chains which is a major component of the heart muscle. Thickening of the heart muscle reduces the blood outflow and increase the ventricular pres...
6 Pages(1500 words)Essay

Social-Emotional Behavioural Disorder

...Social Emotional Behavioural Disorder (SEBD) Table of Content Introduction 3 Different perspective of Social Emotional and Behavioural Disorder – Education 4 Examination of evidences 5 Role of the professionals 7 Evaluation of theories and approaches to inter agency working with SEBD students 8 Conclusion 10 References 11 Bibliographies 13 Introduction Behaviour is an important factor that determines the learning capabilities of an individual. Behaviour can be manifested orally or through actions. Thus any kind of hindrance that is produced in behaviour will affect the learning of individual. The following paper will investigate the fact that how children suffering from Social Emotional and Behavioural disorders can be imparted...
7 Pages(1750 words)Assignment

Contrast of Two Explanations of Social Disorder in Contemporary UK Society

As the process of urbanization takes off and more people start residing in major cities, the fissures start to appear within the apparent harmonious co-existence. There are several reasons why disorderly conduct on part of individuals and groups takes place. Sociologists have proposed numerous theories explaining this phenomenon.

Erving Goffman was an astute observer of society, who immersed himself in the social environment which he was studying. He carefully observed and recorded the ways in which people’s behavior and interpersonal interactions are carried out in everyday life. He notes that “people perform their social roles and, as they do so, they produce social order through their actions and the regu...
6 Pages(1500 words)Article

Post Traumatic Stress Disorder

...Diagnosis Paper: Post-Traumatic Stress Disorder Karyn Sherwood Abnormal Psychology L. Horrell April 3, Introduction and overview of disorder Post-traumatic stress disorder is one of the more severe anxiety disorders defined in psychology. PTSD can occur in people after they have been subjected to psychological trauma, which can be caused by means of any one event that may force a person to feel threatened, or involve death, sexual, physical or psychological virtues. The disorder takes place after the person has experienced the traumatic event. According to the American Psychiatric Association, the diagnostic criteria for PTSD consists of the exposure to a traumatic event; persistent re-experiencing of the event; persistent avoidance...
24 Pages(6000 words)Term Paper

Abnormal Psychology - Catatonia Disorder

...Catatonic Catch I. Introduction The movie, Awakenings, is set sometime in the late 1969 in which a caring and dedicated physician, Dr. Malcolm Sayer got a job at a local hospital in the Bronx of New York. He was assigned to handle psychologically challenged patients which include catatonic ones who survived encephalitis lethargic from 1917 to 1928. Encephalitis is a CNS Disorder that manifests with lethargy sleep cycle disturbances, extrapyramidal symptomatology, neuropsychiatric manifestations, ocular features and cardio respiratory abnormalities (Lopez-Alberola et al., 2009). One of his patients was a certain Leonard Lowe, the character in the movie who displayed symptoms of catatonia. Leonard lost the ability to write and to move...
9 Pages(2250 words)Coursework

Attention Deficit Hyperactivity Disorder

There has also been a long debate and research over the question that whether parents should medicate a child with ADHD. Many doctors and analysts say that medication is the best solution for such children; others say medication should simply not be used on children so young, and some say that medication should never be used alone or as a substitute for other treatments.
The current treatments that are available for ADHD are for reducing the symptoms and improving functioning. There are no specific treatments that could completely cure the disorder. This is because there are primarily no biological tests that would show that a child is suffering from AHDH, these are merely symptoms that would help in the diagnosis (Passmore 1...
8 Pages(2000 words)Assignment

Attention Deficit Hyperactivity Disorder Diagnosis

...Attention deficit hyperactivity disorder Introduction Experts have different views on attention deficit disorder also known as Attention deficit hyperactivity disorder (ADHD) regarding diagnosis, medication and dependency in children resulting from use of stimulant. Minors under medication to prevent ADHD have been on the rise for the last 3 decades in the U.S. The diagnosis of ADHD varies, some states shows a high percentage of diagnosis. Production of stimulants such as Ritalin for ADHD treatments is on the rise, with scientists explaining that it is recommended for treatment. According to Schwarz and Cohen, approximately 11% of children are under medication. Authors have pointed out that one boy in every five high school boys have...
6 Pages(1500 words)Term Paper
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Essay on topic Endocrine Disorder Acromegaly for FREE!

Contact Us