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Medical Reesearch Critique - Book Report/Review Example

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In Comparison of hospital and home intravenous antibiotic therapy in adults with cystic fibrosis (Esmond, Butler, & McCormack, 2006), the authors set forth their findings obtained during a research project to compare intravenous ("i.v.") antibiotic therapy for adults with cystic fibrosis in a hospital setting versus a home setting…
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Medical Reesearch Critique
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Download file to see previous pages Esmond et al., do a good job of comparing, evaluating, and presenting the relevant data as they establish the need for further research on the subject of whether it is more beneficial to allow adult cystic fibrosis patients to self-administer a regimen of i.v. antibiotics or to require them to obtain such treatment in a hospital.
Ethics. Medical research ethics are of utmost importance, and it is "of particular interest to understand how such researchers go about the task of defining ethical research within their own sphere" (Daly, 1996, p. 51). The ethics of Esmond and her team are consistently in line with established practices, and obtaining approval from the Local Health Authority Research Ethics Committee prior to conducting the research (Esmond et al., 2006), p. 55), was compliant with the standard protocols, as "studies that involve testing or observation of people must be authorized by an institutional review board" (Orentlicher, 2005, p. 25). There was no coercion or influence exerted upon the study participants and, in fact, potential participants were volunteers who were pre-screened to ensure sufficient lung function and clinical suitability. Patients were provided with a framework to assist them in determining their suitability for self-management of acute respiratory infection, ensuring a good mix of those who preferred the hospital option with those who did not. Further, the participants were selected in consultation with the cystic fibrosis team which ensured that the i.v. antibiotic therapy was being used as a bona fide treatment modality rather than simply a symptom control for terminal patients. Finally, the privacy of the participants was controlled through the assignment of a number that was used throughout the process. In terms of professional ethics, it would be hard to imagine a more circumspect study than that considered here.
Research Problem. The authors clearly identify the research objective in their "Aim of Study" section (p. 54). The study is designed to compare:
home therapy with traditional hospital therapy for clinical outcome and quality of life in adult CF patients being treated with i.v. antibiotics for acute respiratory exacerbations, once the patient had chosen where they undertook treatment. (2006, p. 54)
The study lacks a formal hypothesis, but offers a statement of intention regarding, in part, the purpose of informing the service department for the purposes of resource allocation planning. In this way, it impacts the nursing profession as the issue of staff planning will directly bear on the process of i.v. treatment of CF patients should a home-based regimen prove effective. It should be noted, however, that this program is for adult CF patients who prefer to self-administer the treatment at home and those who do not meet these or other criteria would remain hospitalized for the duration of the treatment, rendering little impact on staffing levels. Overall, the presentation of the problem is well-done.
Research Literature Review. The literature review in this article, though more brief than some, seems appropriate. It notes that there have been several studies comparing home vs. hospital treatments and that the conclusions are not ...Download file to see next pagesRead More
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