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Effects of Rumatoid Arthritis on the Human Body - Term Paper Example

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People of all ages, male and female, are susceptible to inflammatory diseases. These disorders such as rheumatoid arthritis are catabolic conditions that lead to loss of lean tissue and related functional abnormalities that alters energy and protein metabolism and that lead to changes in body composition…
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Effects of Rumatoid Arthritis on the Human Body
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Download file to see previous pages Though it can be controlled, it can be progressive if left untreated. Most important, it is not a terminal illness, if diagnosed early and treated appropriately. The human body consists of about 300 individual bones, connected by more than 140 joints. To function, a joint also requires ligaments, tendons and muscle tissue. It was once believed that bones were relatively inert once they were formed. Today it is known that bone is constantly turned over. Two special types of cells carry out remodeling and repair work; the osteoclasts which remove bone and the osteoblasts which are responsible for forming new born. Both of the two cells participate in mending of broken bones. Arthritis works by impacting on the balance between the osteoclasts and osteoblasts. The body consists of only three types of joints the synarthroid or fibrous joints, these are the ones separating the plates that form the skull, there is the amphiarthroidal or cartilaginous joints, which are responsible for the limited movement in the intervertebral bones and finally the diarthroidal or synovial joints which are highly mobile. The first two due to their level of movement are not affected by rheumatoid arthritis (RA), however, the highly mobile diarthroidal or synovial joints are the target of RA (Loebl, Lockshin and Paget, 2002, pgs. 39-40). This is especially so in the small joints of the hands and feet, the hips, knees, elbows and shoulder. As the disease progresses more and more joints get affected. RA is a degenerative disease of the joints. It is more serious and debilitating than osteoarthritis. The symptoms include swollen, painful and stiff joints. These symptoms can occur at any stage even in young children, although they usually develop later...
There is a great deal of research being undertaken on arthritis, most of these have predominantly focused on the study of the cells of the immune system that create inflammation. However, still, a lot more needs to be known about RA. There is a need to research more on the role that genetic predisposition plays in RA. Weyand and Goronzy had claimed that the prevalence of the disease is increased in the first-degree relatives of RA patients, with a sibling occurrence risk estated at between 2.8 and 12.1 percent, however, no actual evidence has been released to prove the familial aggregation of RA. Another aspect that needs research on is the causes and treatment of RA. Research conducted has been inconclusive about what is the real cause of RA and the treatment of RA mainly comprises of management steps as well as pain reduction pills. Clearly, this demonstrates the scope of RA that is yet to be shed light on. The good news is that scientists are making rapid progress in understanding the complexities of rheumatoid arthritis: how and why it develops, why some people get it and others do not, why some people get it severely than others. Results fro research are having a positive impact today, enabling people with rheumatoid arthritis to remain active in life, family and work for longer than was possible several years ago.
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