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The trans conformation of acetylcholine binds to the muscarinic receptor, whereas the gauche conformation binds to the nicotinic receptor (MSU).
The production of the desired product requires the development of an…
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Download file to see previous pages Secondly it will require a description on the introduction, removal and transformation of functional groups so as to achieve expected functionality in molecule. Thirdly it requires knowledge of the centers of stereoisomerism that are created or influenced.
The steps in any synthesis are more or less dependent rather than discrete. The assembly of the molecular framework is dependent on structure and functionality of starting materials that are available, selectivity both regio and sterio of reactions for combinations and loss or relocation of functional groups of intermediate compounds in assembling final products.
In conclusion, a successful syntheses route must produce desired product in reasonable good yield and with efficiency in terms of time of reaction and also byproducts. Not all processes can achieve 100% yield. The protection of existing desired functional groups is importantly inclusive of blocking of undesired reactions and activating groups. Knowledge on the introduction and removal of such groups is ...Download file to see next pagesRead More
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