The aim of the report “Physical and Chemical Structure of Penamecillin” is to examine penamecillin. It has a molecular weight of 406.45278 g/mol with a molecular formula of C19H22N2O6. It is a monoclinic crystalline compound. The compound has a density of 1.376g/cm3…
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CAS name for penamecillin is (2s, 5r, 6r)-3, hydroxymethyl (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate , 3-dimethyl-7-oxo-6-[(phenylacetyl) amino]-4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid (acetyloxy) methyl ester. Furthermore, the CAS registry number for penamecillin is 983-85-7, and the compound InChIKey, is NLOOMWLTUVBWAW-UHFFFAOYSA-N (PubMed, ch 1).
Penamecillin has a molecular weight of 406.45278 g/mol with a molecular formula of C19H22N2O6. It is a monoclinic crystalline compound (PubChem, ch 4). The compound has a density of 1.376g/cm3, a boiling point of 648.774°c at 760 mmHg, with a melting point range of 105.5 °c to 111 °c, and a refractive index of 1.609 (Gibaldi And Schwartz, 362 ). It is moderately soluble in water but insoluble in petroleum ether. However, penamecillin is very soluble in methanol, ethanol, ethyl acetate, and benzene. It is also readily soluble in dimethylsulfoxide, chloroform, acetone, trichloromethane, and ether. Furthermore, it is an unstructured crystalline white powder with the precise optical rotation of +269 deg, at 20 deg C/D methanol. It also possesses a flash point of 346.2°C, with an inflammable limit of 364°C when it is a settled powder, and 442°C when it is in form of spun powder. Furthermore, it has a slight characteristic odor, and its decomposition temperature is > 105 °C. In terms of stability and reactivity, penamecillin is stable at ambient temperatures and should be kept away from heat or ignition sources. It is also a readily biodegradable compound even though it is not a bioaccumulation or eco-toxicity compound (PubChem, ch 4). ...Download file to see next pagesRead More
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