Ethanol effect on kidney - Article Example

Download file to see previous pages Therefore, chronic abuse of ethanol impairs the sodium level of the kidneys by affecting the liver function which can also result in acute kidney failure in a few cases. To further understand the ill effects of ethanol for human body and the society in general, the paper will aim at exploring the site of action of ethanol alongside the pharmacokinetics and the pharmacodynamics of ethanol along with other functional and structural complexities. Based on the analysis, the extent and the nature of effects which ethanol leaves on the renal system and the human body as a general may be generalized.
Ethanol, which is most commonly consumed via intake of alcohol, has been known for many years for its intoxicating and pleasant effects. The secret to how ethanol affects brain function which in turn affects the entire human body have been revealed by recent studies. A decade ago, a study conducted by NIH Institute of Abuse and Alcohol achieved a breakthrough when the membrane channel of the brain activated by ethanol was discovered. This channel is also called the G Protein is constitutes various brain cells and it affects the potassium channel which in turn manages various brain functions. More recent studies indicate that the part of the molecule connected to GIRK actually has a site, and ethanol tends to assist GIRK in binding to that site. Thus the site may also be referred to as alcohol-binding in nature. Thus, this is the point where ethanol tends to bind GIRK. In other words, the site where GIRK is connected contains an amino acid sequence supports ethanol`s binding ability. However, once the mind is addicted to ethanol, chances for ethanol abuse increases which pose a risk for renal failure. In other words, alcohol binding site isn`t the only site where ethanol affects the body function, instead it also interferes with liver and kidney functions. (Acton 66)
Research indicates that ethanol directly ...Download file to see next pagesRead More