Nobody downloaded yet

Evaluate the evidence that regulatory T cells maybe be successfully used to prevent graft versus host disease - Research Paper Example

Comments (0) Cite this document
Graft versus Host Disease (GvHD) is an immunological response to what the human body recognises as foreign proteins delivered into the body by transplantation. It has been researched and experiments have been carried out to determine whether a certain subsets of regulatory T…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER95.3% of users find it useful
Evaluate the evidence that regulatory T cells maybe be successfully used to prevent graft versus host disease
Read TextPreview

Extract of sample
"Evaluate the evidence that regulatory T cells maybe be successfully used to prevent graft versus host disease"

Download file to see previous pages A main immunological technique that is used to measure regulatory T cell frequency is flow cytometry; other methods used are immunohistochemistry staining involving studying skin biopsies and ELISAs. All evidence proved strong in correlation with the hypothesis and suggests that CD4 CD25 FOXP3 Tregs could provide a future for the treatment of GvHD.
Transplantation is the process of obtaining tissues or organs or cells and placing them in the same or different individual. The organs, tissues and cells that are transferred from one individual to another are called grafts. The person who donates the graft is called donor and the one who recieves the graft is called recipient. Heart, kidney, cornea, liver, pancreas, lungs and bone marrow are transplanted from one person to another. There are two types of transplantation: autograft (transplant from one region to another of the same indivudual and Syngraft or Isograft (Transfer of graft between individuals of same species). ( Khan, 2009).
Graft versus host disease is the series of events that occurs after the transplantation of the donor T –cells with the stem cell graft. This is a donor T-cell mediated syndrome where the T cells in the graft shows their immune response. This response creates tissue damage. ( Beres and Drobyski, 2013). This is the major difficulty after the stem cell transplantation. The T-cells can recognise the minor and major histocompatibility antigens that are expressed at the host antigen presenting cells. The T-cells gets activated and expands and finally infiltrates and destroys the Graft versus host disease target tissues. The major tissues targeted are liver, gut and skin. This graft versus host hematopoiesis effect is the target for the allogenic stem cell transplantation. (Edinger, 2009). The rejection of the host may occur in first 100 days, where the donor immune cells recognize and attack the host tissues. As ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Evaluate the evidence that regulatory T cells maybe be successfully Research Paper”, n.d.)
Evaluate the evidence that regulatory T cells maybe be successfully Research Paper. Retrieved from https://studentshare.org/biology/1645092-evaluate-the-evidence-that-regulatory-t-cells-maybe-be-successfully-used-to-prevent-graft-versus-host-disease
(Evaluate the Evidence That Regulatory T Cells Maybe Be Successfully Research Paper)
Evaluate the Evidence That Regulatory T Cells Maybe Be Successfully Research Paper. https://studentshare.org/biology/1645092-evaluate-the-evidence-that-regulatory-t-cells-maybe-be-successfully-used-to-prevent-graft-versus-host-disease.
“Evaluate the Evidence That Regulatory T Cells Maybe Be Successfully Research Paper”, n.d. https://studentshare.org/biology/1645092-evaluate-the-evidence-that-regulatory-t-cells-maybe-be-successfully-used-to-prevent-graft-versus-host-disease.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
Stem Cells Cure Diseases
Several projects are now underway to develop transplantation therapies based on stem cells. In addition, stem cells can be modified genetically and have a migratory capacity after transplantation. This brings about the delivery of features that can transform the course of the disease.
10 Pages(2500 words)Research Paper
NKT cells
Thefunction of these NKT cells is closely linked to the development of atopic diseases such as asthma and dermatitis. With the alarming increase of asthma and other allergic diseases in the developing world, there is need for developing effective strategies to combat the high prevalence.
4 Pages(1000 words)Research Paper
US Supreme Court Decision AT&T. versus Hulteen
US Supreme Court Case: AT & T. v. Hulteen The instant case is a United States Supreme Court case in which the primary issue was to determine whether the Pregnancy Discrimination Act (PDA), 42 U.S.C. § 2000e(k) is violated by an employer, when pensions are calculated on the basis of accrual rule, giving less retirement credit for pregnancy than for medical leave (AT & T Corp v.
8 Pages(2000 words)Research Paper
T-cells are MHC-Restricted
There are two principal forms of T-cells. These are CD4+ T-helper cells, and CD8+ T-cytotoxic cells. Each of these is named for the presence of CD4 and CD8 receptors on the surface of each cell type, and also according to the role they play in the immune system.
6 Pages(1500 words)Essay
Stems Cells
Secondly, the paper will focus on the process of cloning as well as its potential for advancements and benefits. The paper will then discuss the benefits of cloning stem cells and the medical benefits of cloning. Finally, the paper will focus on the
4 Pages(1000 words)Research Paper
Stem cells
The invention of Stem cells has made life so much better. Significant progress in the field of stem cells was made by Dr. Ernest A. McCulloch and
4 Pages(1000 words)Research Paper
Stem Cells
f a stem cell therapy, and this is equally part of my motive for addressing this letter to you in an attempt to shed some light on stem cells, and their implication on the kind of therapy you are going to receive. It is thus interesting to inform you that this letter is going to
6 Pages(1500 words)Research Paper
The Principles of Management Communications Used to Successfully Achieve Organizational Objectives
Baack (2012) defines communication as the process through which an individual transmits, receives and processes information. Consequently, communication, as Baack further argues, would entail the transfer of
8 Pages(2000 words)Research Paper
Research on Coronary Heart Disease and Chinese herbal formulas and/or specific herbs to help and/or prevent
Coronary heart disease has become one of the major causes of morbidity and mortality in the United States. With the increased rates of obesity and intake of processed and high cholesterol foods, this issue will likely continue to prevail in US society. In fact, coronary heart disease (CHD) or coronary artery disease (CAD) is said to affect about 14 million people in the United States alone (WebMD, p.
12 Pages(3000 words)Research Paper
Dynamic Host Configuration Protocol
The development and continued evolution of Internet technology has been fairly rapid, in part due to the main principles which still stand today: it should be freely accessible by anyone and it should be free from any forms of control or censorship. This free environment contributed to rapid advances because of so many good ideas pooled together to further enhance an Internet infrastructure that is now ubiquitous in most people's lives and it will be discussed in this paper.
10 Pages(2500 words)Research Paper
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Research Paper on topic Evaluate the evidence that regulatory T cells maybe be successfully used to prevent graft versus host disease for FREE!
logo footer
Contact us:
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us