quora
Nobody downloaded yet

Inhibition of DNA processing in heavy metal carcinogenesis - Essay Example

Comments (0) Cite this document
Summary
It will also do an examination of metal carcinogenesis and its role in topo-1enxyme activity. Exposing human to heavy metals is…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER97.8% of users find it useful
Inhibition of DNA processing in heavy metal carcinogenesis
Read TextPreview

Extract of sample
"Inhibition of DNA processing in heavy metal carcinogenesis"

Download file to see previous pages Nonetheless, although it has been noted that some heavy metals may inhibit SSB (single strand break) rejoining, the effects on single strand break end-processing enzymes has never previously been investigated.
First, an analysis on the DNA replication as a result of topo-1 enzyme will be done. This will show how topo-1 enzyme is responsible for winding of DNA structures. A picture analysis will be included to show evidence of the process. As mentioned earlier, different heavy metals have effects on the living organism’ DNA. The metals will be discussed together with their effects.
This paper also explores inhibition of superoxide dismutases. This enzyme catalysis the dismutation of extremely reactive superoxide ions to generate hydrogen peroxide and numerous lines of evidence propose that these enzymes play significant part in the development and also response to treatment of cancers.
These are enzymes that control under-winding and over-winding of DNA. DNA winding comes from the intertwined nature of its double-helical structure. For instance, during replication of DNA, DNA is overwound before a replication fork. When it is not controlled, it will eventually lead to a halt in DNA replication. A similar process is observed during transcription. To overcome the topological problems resulting from the double helix, topoisomerases are bound to single or double stranded DNA and cut the phosphate spine of the DNA. This untangles the DNA releasing the DNA spine again. Since the chemical composition of the DNA remains the same, the untangled DNAs are chemical isomers. Therefore, topoisomerases are isomerase enzymes which work on the DNA topology.
The N-terminal domain is then preceded by a highly conserved, 421 amino acid core domain that contains all of the catalytic residues except the active site tyrosine. A protease-sensitive and poorly conserved linker domain ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Inhibition of DNA processing in heavy metal carcinogenesis Essay”, n.d.)
Retrieved from https://studentshare.org/biology/1630258-inhibition-of-dna-processing-in-heavy-metal-carcinogenesis
(Inhibition of DNA Processing in Heavy Metal Carcinogenesis Essay)
https://studentshare.org/biology/1630258-inhibition-of-dna-processing-in-heavy-metal-carcinogenesis.
“Inhibition of DNA Processing in Heavy Metal Carcinogenesis Essay”, n.d. https://studentshare.org/biology/1630258-inhibition-of-dna-processing-in-heavy-metal-carcinogenesis.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
CHECK THESE SAMPLES - THEY ALSO FIT YOUR TOPIC
In the context of environmental toxicology, what does 'heavy metal' actually mean
The name often refers to a category name of metalloids (semimetals) and metals associated with eco-toxicity or toxicity potential and contamination (Daffus, 2002). There is an assumption that all heavy-metals and their compounds have properties that are eco-toxic or highly toxic.
6 Pages(1500 words)Essay
DNA
As can be inferred, its inheritance is ruled by Mendelian codominance, wherein IA and IB are codominant alleles, while i is the recessive allele (Campbell and Reece, 2002). Thus, if a parent with a blood type A or B has an I-i, then it is possible that his or her child can have blood type O, especially when the other parent has an I-i or ii genotype.
4 Pages(1000 words)Essay
DNA
The answer lies in deoxyribonucleic acid (DNA), and its unique composition. Like a fingerprint, each person has a unique DNA sequence that contributes to their individuality (NIH). DNA then goes on to encode for unique proteins that act as markers in the blood, which help lab technicians make specific identifications (NIH).
3 Pages(750 words)Essay
Does heavy metal rock music encourage violence in teenagers
Dr. Paul King conducted research in a Memphis hospital among disturbed teenagers. The age of his patients ranged from thirteen to seventeen years, and they were admitted to the hospital for treatment of their drug dependency. Among the two hundred patients interviewed 60% responded that heavy metal music was their primary choice of music.
3 Pages(750 words)Essay
Medical biotechnology and leadership
Such investigations require the synthesis of information from different fields and using this capacity to establish a thorough literature review of the work. Project management skills will be critical in
6 Pages(1500 words)Essay
Heavy metal pollution: causes, effects, analytical methods
Concerns related to heavy metals are due to the chemical properties of the metals rather than their density. Metals which are known as heavy metals are cadmium, lead, zinc, arsenic, mercury, chromium, silver, iron, platinum and copper. These metals occur as natural constituents of the crust of the earth and since they cannot be destroyed or degraded, they are persistent environmental constituents.
4 Pages(1000 words)Term Paper
Heavy Metal and Society
The public view of heavy metal has been consistent since its inception: in the eye of the mainstream citizen, people listen to heavy metal because they are angry, want to shock other people, and in general evade responsibility for being solid members of the community.
7 Pages(1750 words)Essay
Metal Toxicity
Aquatic Metal toxicity depends upon particular water sample's chemical composition such as dissolved organic carbon, oxygen various other elements. Formations of organic and inorganic metal complexes are highly dependent upon the ambient water chemistry (Sunda and Guillard 1976).
4 Pages(1000 words)Essay
Walser, Robert. Heavy Metal: Sounds and Images of Gender
Fiske goes ahead to expose to the readers what the societies’ intention is when it does this. He says that by denying males this opportunity, they feel insecure.
1 Pages(250 words)Essay
DNA
On April 25th, 1953, the now famous scientific pair of Watson and Crick attempted to finally answer this question (Fredholm). They claimed that an elegant molecule called deoxyribonucleic acid, or DNA, was the “God Molecule”, the blueprint for every protein in our body (and the subsequent molecules those proteins go on to make), the stuff of life (What Is DNA?
5 Pages(1250 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Essay on topic Inhibition of DNA processing in heavy metal carcinogenesis for FREE!
logo footer
Contact us:
+16312120006
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us