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The article, diffusible coupling signals from transplanted superchiasmatic nucleus controlling circadian locomotor rhythms involve, an analysis of mammalian suprachiasmatic nuclei transplant. This suprachiastic nucleus (SCN) transmits signals to the brain, organizing circadian…
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Download file to see previous pages Consequently, the authors show how circadian rhythm is produced by the donor tissue and not a consequence of spontaneous recovery of function.
The title, a diffusible coupling signal from transplanted superchiasmatic nucleus controlling circadian locomotor rhythms, is adequate in describing the content of the article. It contains the entire content that is discussed in the article. From the article, the authors’ goal is to show that transplanted SCN can sustain circadian activity rhythms by diffusible signal means. The fact that transplant of SCN restore circadian activity rhythms to ablated animal SCN has motivated the research and discussion in the paper. The other factor is that coupling nature of signals from grafted SCN is unknown and presumed that re-establishment of appropriate synaptic connection is required in functional recovery.
In conclusion, the findings showed that neural afferents are essential for circadian rhythmicity. Additionally, it shows how circadian rhythm of SCN can be relayed to targets. Further, the results demonstrate that diffusible signal is sufficient to rhythmicity restoration. The finding in the paper is significant as it demonstrate how diffusible signal is sufficient in rhythmicity ...Download file to see next pagesRead More
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