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Cigarette Smoking and Fertility - Essay Example

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"Cigarette Smoking and Fertility" paper focuses on women and cigarette smoking where infertility incidence was an issue of meta-analysis printed in 1998. Among the various reproductive systems studied, ovarian tissue is the most researched regarding the effects of exposure to tobacco substances…
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Cigarette Smoking and Fertility
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The article proposes that methodical literature demonstrates that there is a strong link between cigarette smoking and an instance of damaged reproductive function. The main aspect gladly accessible proof on this issue is the universal assertion that possible mechanisms through which cigarette smoking can hamper fertility are diverse, with none being established. In these studies, chemical compounds in tobacco smoke seem to hasten follicular depletion (Soares 40). Moreover, qualitative impacts on follicular maturation, steroidogenesis, embryo development, and fertilization have been documented. Exposure to cigarette substances in animals negatively impacts both pre-and post-implantation competence in embryonic development.

For instance, tobacco inhalation in female mice was demonstrated to be harmful to the early development of the embryo and results in reduced fetal total weight. Direct nicotine injection in rats impedes cleavage of the embryo and considerably decreases the number of cells. It has been acknowledged women who smoke tobacco have a high probability of tubal barrenness and a noticeably high danger of ectopic pregnancy. In a study, the ectopic pregnancy’s OR among smoking women was around 15.69. Tobacco smoking has been illustrated to negatively impact both the cellular and humoral immune systems.

Moreover, it has been hypothesized that such changes may make tobacco smokers more liable to tubal contagions and ensuing infertility. Regarding the effect of tobacco smoking on male, Soares (42) contend that research demonstrates that normal conception in couples having a tobacco-smoking spouse has a considerable decrease in fertility, with an elevated time-to-pregnancy, in situations where cigarette intake is greater than 15 per day. Tobacco smoking does not only alter variations in standard sperm limits but also can impact the quality of the sperm.

Also, biochemical alterations that can decrease the quality of sperms have been published in seminal liquid smokers, and tobacco genotoxicity is indubitable. In various groups analyzing DNA sperm fragmentation in tobacco-smoking and nonsmoking males, it was established that an increased fragmentation rate in tobacco smokers was greatest in pre-and post-swim-up sperm samples. This result is linked to decreased quality of embryos in the IVF phases. Fascinatingly, young, well, fertile tobacco smoking donors were documented not to exhibit a considerable increase in fragmentation in DNA in sperms. Moreover, there is an alteration in the receptiveness of the uterine; male fecundity is undermined in frequent smokers and standard parameters in the sperm are fairly decreased.

Indeed, according to the article, sperm from tobacco smokers have decreased capacity for fertility, and embryos exhibit reduced rates of implantation. Also, spouses at the age of reproduction must be stoutly advised to stop cigarette smoking. 

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