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Mammalian Stem Cells - Research Paper Example

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Mammalian Stem Cells Abstract Mammalian stem cells have offered a tremendous biomedical potential throughout the years. This is because of their ability of self renewal and differentiation into adult cell type. Stem cell biology has thus been made an intense area of study in biology and other clinical potentials…
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Download file to see previous pages However, research has raised ethical and religious issues which oppose the duplication of body tissues. Our research shows that the benefit of mammalian stem cell culture has increasingly become important over the years in the production of antibodies, hormones and other vaccines essential for the treatment of various body ailments. Introduction Stem cells are found throughout the body of an animal. They occur in numerous numbers in the tissues such as the brain, adipose and the muscles. Stem cells help in maintaining the functioning and integrity of the tissues throughout the lifetime of an organism. This is because their main role is the replacement of the differentiated cells which are lost through attrition or other damages. Mammalian stem cells have the capacity of proliferating while maintaining their primitive states. In addition, they also differentiate into other specialized lineage. Due to their expansion and differentiation capabilities, there is high promise in the development of cell based models of human diseases. This is because such diseases can be treated during the cell replacement therapies. Engineers and researchers have developed a theoretical approach and other cell culture systems. All this technologies are vital in the control of stem cell fate which is the ultimate goal to scale up the clinical grade during the production of stem cell therapies. Advancement of stem cells science and broadening of cell culture technology has led to arising of therapies and tissue engineering. This paper work gives an overview of tissue engineering and therapies of mammalian stem cells. It describes the current progress and prospect of stem cells research and its potential application in the medical treatment. Discussion Stem cell technologies and tissue engineering have currently emerged rapidly with an approach of addressing disease problems and other serious body complications. The two technologies are the interdisciplinary fields that use the principle of bioengineering and other sciences towards assembling of the stem cells. This is important in restoring, maintaining and improving the functioning of the cell following their damage by disease or other traumatic processes. It is, therefore, easy to manage incurable diseases and loss of tissue through the successful therapies of artificial transplant of body organs. The general principles of stem cell engineering and tissue therapy are the combination of living cells with other synthetic scaffold to build three dimension living cells. The three dimensional cell structures aid in guiding the growth, organization and differentiation of cells. Synthetic scaffold should be biocompatible and designed in a way that it assists in meeting the nutritional and biological needs of different cells on the body. Their growth factors should be made of soluble peptides that are capable of binding the cellular receptors that provide permissive or preventive response of the cell towards differentiation of the body tissue (Kim and Evans 12). Therapy And Tissue Engineering Fundamentals The concept of tissue engineering started in 1933 when tumor cells from the mouse demonstrated survival ability when they were implanted in the abdominal cavity of an embryo chick. Few decades later the chick’s pancreatic beta cells demonstrated that they responded by releasing insulin depending on the concentration of glucose in the body. In 1980, through the principle of tissue enginee ...Download file to see next pagesRead More
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